Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Bax; Bcl-2-associated X protein; CHOP; C/EBP-homologous protein 10; DNA; dezoxiribonucleic acid; FITC; fluorescein isothiocyanate; GAPDH; (Glyceraldehyde 3-phosphate dehydrogenase; GRP78; glucose-regulated protein 78; HIF1α; hypoxia inducible factor 1α;
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Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Actin dynamics; Rho GTPases; dendritic spines; postsynapse; Abi-1; Abelson interacting protein 1; Abp1; actin binding protein 1; ACTN4; α-actinin-4; ADF; actin-depolymerizing factor; ADHD; attention deficit/hyperactivity disorder; ADNP; activity-dependen
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; ABC; ATP-binding cassette; EGF; epidermal growth factor; EMT; epithelial-to-mesenchymal transition; IGF; insulin growth; MET; mesenchymal-to-epithelial transition; MMP; matrix metalloprotease; PD-L1; programmed death ligand 1; PDGFR-A; platelet-derived gr
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; AKT; protein kinase B; ATF4; activating transcription factor 4; cAMP; cyclic adenosine monophosphate; CCL5; (C-C motif) ligand 5; CNS; central nervous system; 4EBP1; 4E (elF4E) binding protein; ECM; extracellular matrix; ERK; p44/p42 extracellular signal-
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Dendritic spine; Synaptic plasticity; Neurodegenerative diseases; Psychiatric disorders; Glutamate receptor; Calcium signaling; ADHD; attention deficit hypersensitive disorders; FXS; Fragile X-syndrome; CNS; central nervous system; GABA; gamma amino butyr
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Neurotrophins; Signalling endosome; Endosome acidification; Trk receptors; Membrane motility; Receptor internalization; AP-2; adaptor protein complex 2; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; EEA1; early endo
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; CASK; calcium/calmodulin-dependent serine protein kinase; COS-7; African green monkey kidney fibroblast-like cell line; Drp1; dynamin-related protein 1; FAK; focal adhesion kinase; hnRNPA2B1; heterogeneous nuclear ribonucleoprotein A2B1; K2P; potassium se
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Bile; iTRAQ; Biomarker; Olfactomedin-4; Syntenin-2; Ras-related C3 botulinum toxin substrate 1;
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; S1P; sphingosine-1-phosphate; HDL-S1P; HDL-bound S1P; albumin-S1P; albumin-bound S1P; AKT; protein kinase B; SPHK; sphingosine kinase; PI3K; phosphatidylinositol 3-kinase; S1PR1-3; S1P receptor 1-3; RAC-1; ras-related C3 botulinum toxin substrate 1;
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; GLI1/2/3; glioma-associated oncogene homologue 1/2/3; PTCH; patched; SMO; smoothened; SUFU; suppressor of fused; CDO; CAM-related/downregulated by oncogenes; BOC; brother of CDO; GAS1; growth arrest-specific 1; PKA; protein kinase A; GSK3β; glycogen synt
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Rho; Ras homolog gene; Rac1; Ras-related C3 botulinum toxin substrate 1; Cdc42; cell division cycle 42; RhoA; Ras homolog gene family member A; Methylmercury; Neuronal migration; Cerebral cortex; Proliferation; Radial glial scaffold; Rho family proteins;
IL-21 alleviates allergic asthma in DOCK8-knockout mice
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; DOCK8 gene; Allergic asthma; Ovalbumin; Murine model; IL-21; rmIL-21; recombinant mouse interleukin-21; DOCK8; dedicator of cytokinesis 8; STAT3; signal transducer and activator of transcription 3; TYK2; tyrosine kinase 2; DIDS; DOCK8 immunodeficiency syn
Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Activated protein C (APC); Endovascular restorative neurosurgery; Mechanical neurothrombectomy; Neuroprotection; Neurorestoration; Stroke; Thrombolysis; (AIS); acute ischemic stroke; (Akt); protein kinase B; (APC); activated protein C; (BBB); blood-brain
Seeing is understanding: Salmonella's way to penetrate the intestinal epithelium
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; ARNO; adenosine diphosphate (ADP) ribosylation factor nucleotide exchange factor; BMP; bone morphogenetic protein; Cdc42; cell division control protein 42 homolog; CFU; colony forming unit; EGF; epithelial growth factor; Ets; E26 transformation-specific;
Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Arhgef1; Rho guanine nucleotide exchange factor 1; GEF; guanine nucleotide exchange factor; RhoA; Ras homolog gene family, member A; Rac1; Ras-related C3 botulinum toxin substrate 1; Cdc42; cell division control protein 42; DAPI; 4â²,6-diamidino-2-phenyl
Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; HG; high glucose; GEFs; guanine nucleotide exchange factors; GSIS; glucose-stimulated insulin secretion; NOD mice; nonobese diabetic mice; Nox2; phagocyte-like NADPH oxidase; Rac1; Ras-related C3 botulinum toxin substrate 1; ROS; reactive oxygen species;
cDNA cloning, expression and immune function analysis of a novel Rac1 gene (AjRac1) in the sea cucumber Apostichopus japonicus
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Apostichopus japonicus; Ras-related C3 botulinum toxin substrate 1; Expression analysis; Vibrio splendidus infection;
The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; DIAPH1; diaphanous 1; EGR1; early growth response 1; F actin; filamentous (F) actin; Fos; gene for c-Fos; G actin; globular (G) actin; GSK3B; glycogen synthase kinase 3 beta; Ex vivo I/R; ex vivo ischemia/reperfusion; H/R; hypoxia/reoxygenation; I/R; isch
Synthetic triterpenoids inhibit GSK3β activity and localization and affect focal adhesions and cell migration
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; CDDO; 2-cyano 3,12-dioxooleana-1,9 (11)-dien-28-oic acid; Im; imidazolide; Me; methyl ester; FAK; focal adhesion kinase; GSK3β; Glycogen Synthase Kinase 3 Beta; APC; adenomatous polyosis coli; DMSO; dimethyl sulfoxide; NaCl; sodium chloride; LiCl; lithiu
Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; 8-OHdG; 8-hydroxy-2-deoxyguanosine; ABL1; ABL proto-oncogene 1; AhpC; alkyl hydroperoxide reductase; AKT1; V-Akt murine thymoma viral oncogene homolog 1; APEX1; endonuclease apurinic/apyrimidinic endodeoxyribonuclease 1; ARG1; arginase 1; ARG2; arginase 2
Functional integration of complex miRNA networks in central and peripheral lesion and axonal regeneration
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; AAV(s); adeno-associated virus(es); ADAM; a disintegrin and metalloprotease; AGO(2); argonaut (2); AKT; protein kinase B; APC; adenomatous polyposis coli; ASO(s); antisense oligonucleotide(s); ATF3; activating transcription factor 3; BBB; blood brain barr
miR-4516, a microRNA downregulated in psoriasis inhibits keratinocyte motility by targeting fibronectin/integrin α9 signaling
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; miR-4516; hsa-miR-4516; NN; healthy skin; NL; psoriasis non lesional skin; LL; psoriasis lesional skin; FN1; fibronectin 1; ITGA9; integrin subunit α9; Rac1; Ras-related C3 botulinum toxin substrate 1; RhoA; Ras homolog gene family, member A; Cdc42; Cell
DOCK8 deficiency: Insights into pathophysiology, clinical features and management
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Actin; CDC42; Combined immunodeficiency; Dedicator of cytokinesis; DOCK2; DOCK8; Hyper IgE syndrome; Primary immunodeficiency; RAC1; STAT3; AR-HIES; autosomal recessive hyper IgE syndrome; AD-HIES; autosomal dominant hyper IgE syndrome; CDC42; cell divisi
Redox signaling in the gastrointestinal tract
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci
Exosomes and nanotubes: Control of immune cell communication
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; APC; Antigen presenting cell; Cdc42; Cell division control protein 42; DC; Dendritic cell; EBV; Epstein-Barr virus; ESCRT; Endosomal sorting complex required for transport; HIV; Human immunodeficiency virus; ICAM-1; Intercellular adhesion molecule 1; IgA;
EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Arf6; ADP-ribosylation factor 6; Cdc42; Cell division control protein 42; ERK1/2; Extracellular signal-regulated kinases; GEF; Guanine nucleotide exchange factor; GDP; Guanosine diphosphate; GTP; Guanosine triphosphate; GGTI; Geranylgeranyl transferase in
Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; ABTS; 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid); AML; acute myeloid leukemia; ApnA; diadenosine polyphosphates; ATP; adenosine-5â²-triphosphate; ATX; autotaxin; BALF; bronchoalveolar lavage fluid; bis-pNPP; bis(p-nitrophenyl) phosphate; BLM
Role of Frizzled6 in the molecular mechanism of beta-carotene action in the lung
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; BC; β-carotene; BCMO1; beta-carotene 15,15â²-monooxygenase 1; Fzd6; frizzled homologue 6; Cthrc1; collagen triple helix repeat containing 1; GO; Gene Ontology; DAVID; Database for Annotation Visualization and Integrated Discovery; DO; Disease Ontology;
Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; AS160; Akt substrate 160; EDL; extensor digitorum longus; FWHM; Full Width at the Half Maximum; GAP; GTPase activating protein; KO; knockout; PAK1; p21 protein-activated kinase 1; PI3K; phosphatidylinositol 3-kinase; Rac1; Ras-related C3 botulinum toxin s
Combined CpG and poly I:C stimulation of monocytes results in unique signaling activation not observed with the individual ligands
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; TLRs; Toll-like receptors; CpG; unmethylated CpG oligodeoxynucleotides; poly I:C; polyinosinic-polycytidylic acid; NO; nitric oxide; iNOS; inducible nitric oxide synthase; CREB; cAMP response element-binding protein; NFκB; nuclear factor κB; PRRs; pat
A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; cAMP; cyclic 3â²5â²-adenosine monophosphate; CCNT2; cyclin T2; CMML; chronic myelomonocytic leukemia; CSF1; colony-stimulating factor 1; CUX1; cut-like homeobox 1; EGR2; early growth response 2; GFI-1; growth factor independent-1; KLF4; Krüppel-like fa
8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; 8-oxoG; 8-oxo-7,8-dihydroguanine; 8-oxodG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; 8-OH-Ade; 8-oxo-7,8-dihydroadenine; APE1; apurinic/apyrimidinic endonuclease 1; DNA BER; base excision repair; FapyG; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; FU; fluore
Dendritic spine plasticity as an underlying mechanism of neuropathic pain: Commentary on Tan et al.
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; AMPA; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; aPKC; atypical protein kinase C; BDNF; brain derived neurotrophic factor; CCI; chronic constriction injury; DHPG; dihydroxyphenyglycine; FMRP; fragile X mental retardation protein; IL-6; inte
Research ArticleCdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Palmitate; Small GTPases; MAP3K; JNK; NAFLD; SFA; saturated free fatty acids; JNK; c-Jun NH2-terminal kinase; Cdc42; cell division cycle protein 42; Rac1; ras-related C3 botulinum toxin substrate 1; NAFLD; non-alcoholic fatty liver disease; IRE1; inositol
TGFβ and BMP-2 regulate epicardial cell invasion via TGFβR3 activation of the Par6/Smurf1/RhoA pathway
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; ALK; Activin Receptor-Like Kinases; AVC; Atrioventricular Endocardial Cushion; BMP; Bone Morphogenetic Protein; Cdc42; Cell division control protein 42 homolog; EMT; Epithelial-Mesenchymal Transformation; GFP; Green Fluorescent Protein; GIPC; GAIP-interac
DISC1-binding proteins in neural development, signalling and schizophrenia
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; DISC1; Schizophrenia; Neurodevelopment; Signalling; Synapse; Association studies; APP; Amyloid precursor protein; ATF4; Activating transcription factor 4; BACE1; β-site APP-cleaving enzyme-1; BBS4; Bardet-Biedl syndrome 4; CEP290; Centrosomal protein 2
CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Act1; activator of NF-κB; ACM; adult cardiomyocytes; ANF; atrial natriuretic factor; AP-1; activator protein-1; AT1; angiotensin II type 1 receptor; ATRAP; AT1-receptor-associated protein; ARAP1; type 1 Ang II-receptor-associated protein 1; C/EBP; CCAAT/
Hepatocellular carcinoma with progenitor cell features distinguishable by the hepatic stem/progenitor cell marker NCAM
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; HCC; hepatocellular carcinoma; NCAM; neural cell adhesion molecule; CK19; cytokeratin 19; IM; intrahepatic metastasis; CC; cholangiocellular carcinoma; FGFR; fibroblast growth factor receptor; NK; natural killer; GPI; glycosyl-phosphatidylinositol; DAPI;
Unexpected wide substrate specificity of C. perfringens α-toxin phospholipase C
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; Ala and A; alanine; Asp and D; aspartic acid; BcPLC; Bacillus cereus phospholipase C; BSA; bovine serum albumin; CbPLC; Clostridium bifermentans phospholipase C; CDCl3-d; deuterated chloroform; Chol; cholesterol; CpPLC; Clostridium perfringens phospholipa
Pathway-based genome-wide association analysis identified the importance of EphrinA-EphR pathway for femoral neck bone geometry
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; PAK1; p21-activated kinase 1; FAK1; PTK2 protein tyrosine kinase 2; EphA7; Eph receptor A7; PIK3CG; phosphoinositide-3-kinase, catalytic, gamma; PAK7; p21-activated kinase 7; RASA1; RAS p21 protein activator 1; FYN; FYN oncogene related to SRC, FGR, YES;
Research ReportChemokine-like factor 1, a novel cytokine, induces nerve cell migration through the non-extracellular Ca2+-dependent tyrosine kinases pathway
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; CKLF1; chemokine-like factor 1; PYK2; proline-rich tyrosine kinase 2; F-actin; filamentous actin; CCR4; chemokine (C-C motif) receptor 4; PYK2-DN; PYK2-dominant-negative; Rac1; Ras-related C3 botulinum toxin substrate 1; Rac1-DN; Rac1-dominant-negative; P
Effects of Antidiabetic and Antihyperlipidemic Agents on C-Reactive Protein
Keywords: زیر بغل سم بوتولینوم C3 مرتبط با ریز 1; A1c; glycated hemoglobin; CRP; C-reactive protein; DM; diabetes mellitus; HDL-C; high-density lipoprotein cholesterol; hsCRP; high-sensitivity CRP; ICAM-1; intercellular adhesion molecule 1; IL; interleukin; LDL-C; low-density lipoprotein cholesterol; MCP