دانلود مقالات ISI درباره Scd1 + ترجمه فارسی

Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents

Keywords: Ac; acetyl; ADME; absorption, distribution, metabolism, and excretion; aq.; aqueous; AUC; total area under the blood concentration-time curve; bid; bis in die (twice per day); Boc; (tert-butoxy)carbonyl; Bu; butyl; Bz; benzoyl; cLogP; calculate logarith

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice

Keywords: ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; DF; Gangjihwan; FAS; fatty acid synthase; HE; hematoxylin-eosin; HFD; high fat di

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation

Keywords: ER stress; HCC; SCD1; Sorafenib; T-ICs;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells

Keywords: Annexin V; FITC-conjugated annexinV; BCA; bicinchoninic acid; BNIP3; Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3; CBP; CREB-binding protein; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; CHIP; chromatin immunoprecipitation; CHOP; CCAAT-en

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effects of gomisin N against hepatic steatosis through AMPK activation

Keywords: Gomisin N; Nonalcoholic fatty liver disease; Lipogenesis; AMP-activated protein kinase; Sterol regulatory element-binding protein 1c; High-fat diet; ACC; Acetyl-CoA carboxylase; AMPK; Adenosine monophosphate (AMP)-activated protein kinase; CPT 1; Carnitin

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier

Keywords: IFE; interfollicular epidermis; SCD1; stearoyl-CoA desaturase 1; TEWL; transepidermal water loss; WAT; white adipose tissue;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Dihydrosterculic acid from cottonseed oil suppresses desaturase activity and improves liver metabolomic profiles of high-fat-fed mice

Keywords: Fatty acid oxidation; Desaturation; Metabolomics; Bioactive lipids; Nuclear magnetic resonance (NMR) spectroscopy; 18:2; linoleic acid-rich diet; 18:2n6; linoleic acid; CHO; carbohydrate; CPFA; cyclopropyl fatty acid; CSO; cottonseed oil; DHSA; dihydros

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury

Keywords: Binge ethanol consumption; FGF21; Chronic ethanol consumption; Alcoholic liver disease; ACSS2; acyl-coenzyme a synthetase short-chain family member 2; ADH 1 and 2; alcohol dehydrogenase 1 and 2; ALDH1α1; aldehyde dehydrogenase 1 alpha 1; ALD; alcoholic l

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance

Keywords: StAR; steroidogenic acute regulatory protein; NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered solution; FBS; fetal bovine serum; ITS-X; insulin-transferrin-selenium-ethanolamine

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of autophagy by mitochondrial phospholipids in health and diseases

Keywords: ALCAT1; lysocardiolipin acyltransferase 1; ALE1; lysophospholipid acyltransferase (yeast); AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATGL; adipose triglyceride lipase; AVT1; amino acid vacuolar transport; BNIP3; BCL2/adenovirus E1B

دانلود رایگان متن کامل مقاله ISI 84 صفحه سال انتشار : 2017 سفارش ترجمه

Daidzein reduces the proliferation and adiposeness of 3T3-L1 preadipocytes via regulating adipogenic gene expression

Keywords: Daidzein; 3T3-L1 preadipocytes; Proliferation; Adipogenesis; Arachidonic acid (PubChem CID: 444899); Daidzein (PubChem CID: 5281708); Dexamethasone (PubChem CID: 5743); Dimethyl sulfoxide (PubChem CID: 679); Isopropanol (PubChem CID: 3776); Oil Red O (Pub

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

SCD1 deficiency protects mice against ethanol-induced liver injury

Keywords: Alcoholic fatty liver disease; SCD1; De novo lipogenesis; Inflammation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Vitamin A deficiency suppresses high fructose-induced triglyceride synthesis and elevates resolvin D1 levels

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HFSC; high fructose corn syrup; ALT; alanine aminotransferase; AST; aspartate aminotransferase; RBP4; retinol binding protein 4; FGF21; fibroblast growth factor 21; CRP; C-reac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice

Keywords: miR-378; Futile cycle; Lipolysis; Energy homeostasis; Obesity; SCD1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Transcriptional regulation analysis of FAM3A gene and its effect on adipocyte differentiation

Keywords: FAM3A; family with sequence similarity 3, member A; G6PD; glucose-6-phosphate dehydrogenase; PPARG(2); peroxisome proliferator-activated receptor gamma(2); C/EBPα; CCAAT/enhancer binding protein alpha; C/EBPβ(C/EBPβbeta); CCAAT/enhancer binding protein

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Symplocos cochinchinensis enhances insulin sensitivity via the down regulation of lipogenesis and insulin resistance in high energy diet rat model

Keywords: SCE; Symplocos cochinchinensis ethanol extract; HFS; high fructose and saturated fat; T2DM; type 2 diabetes mellitus; SCD1; stearoyl - CoA desaturase; SREBP-1c; sterol regulatory element binding protein 1; FAS; fatty acid synthase; G6Pase; glucose 6 pho

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling

Keywords: AA; arachidonic acid; Acox1; acyl-CoA oxidase; ATGL; adipocyte triglyceride lipase; CCTα; phosphate cytidylyltransferase 1, choline α; CEPT; choline/ethanolaminephosphotransferase 1; CE; cholesterol esters; CHOL; cholesterol; CM; chylomicrons; CPT1; car

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy

Keywords: Fasting; Lipophagy; Liver steatosis; Oxidative stress; Superoxide dismutase; ACC; acetyl CoA-carboxylase; ALT; alanine aminotransferase; apoB; apolipoprotein B; BSA; bovine serum albumin; ER; endoplasmic reticulum; FAS; fatty acid synthase; GLU; glucose;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleHepatitis C viral proteins perturb metabolic liver zonation

Keywords: HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PP; periportal; PV; perivenous; FASN; fatty acid synthase; ACSL3; acyl-CoA synthetase long-chain family member 3; SCD1; stearoyl-CoA desaturase; GS; glutamine synthetase; HCV; Metabolic liver zonation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleThioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; TXNIP; thioredoxin-interacting protein; PA; palmitic acid; SA; stearic acid; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; SCD1; stearoyl-CoA desaturase-1; LPL; lipopr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Maternal supplementation with n-3 long chain polyunsaturated fatty acids during perinatal period alleviates the metabolic syndrome disturbances in adult hamster pups fed a high-fat diet after weaning

Keywords: VLDL; very low density lipoproteins; LDL; low density lipoprotein; HDL; high density lipoprotein; AUC; area under the curve; CS; citrate synthase; DGAT2; diacylglycerol O-acyltransferase 2; FAS; fatty acid synthase; FCCP; carbonyl cyanide p-trifluorometho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification and expression pattern of two novel alternative splicing variants of EEF1D gene of dairy cattle

Keywords: eEF1; eukaryotic elongation factor 1; eEF1A; eukaryotic elongation factor 1A; eEF1B; eukaryotic elongation factor 1B; eEF1Bγ; eukaryotic elongation factor 1γ; eEF1Bα; eukaryotic elongation factor 1α; eEF1Bδ; eukaryotic elongation factor 1Bδ; EEF1D;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice

Keywords: MKP-3; MAP kinase phosphatase 3; Dex; Dexamethasone; FOXO1; forkhead box protein O1; GC; glucocorticoid; DUSP6; dual specificity protein phosphatase 6; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphoinosit

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Multi-faceted integrated omics analysis revealed parsley (Petroselinum crispum) as a novel dietary intervention in dextran sodium sulphate induced colitic mice

Keywords: AA; amino acid; Ala; alanine; Asn; asparagine; Asp; aspartic acid; Arg1; arginase 1; Ccl; chemokine (C-C motif) ligand; Cebp/d; CCAAT/enhancer binding protein (C/EBP), delta; Cd163; cluster of differentiation 163; Cxcl; chemokine (C-X-C motif) ligand; DAI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells

Keywords: ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Stearoyl-CoA desaturase regulates inflammatory gene expression by changing DNA methylation level in 3T3 adipocytes

Keywords: SCD1; stearoyl-CoA desaturase 1; WAT; white adipose tissue; TNFα; tumor necrosis factor-α; IL6; interleukin 6; MCP1; monocyte chemoattractant protein 1; LPS; lipopolysaccharide; Il10ra; interleukin 10 receptor a; Il6st; interleukin 6 signal transducer;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH)

Keywords: ATGL; adipose triglyceride lipase; ACC1; acetyl-CoA carboxylase; ACSL1; long-chain fatty-acid-coenzyme A ligase; ap2/FABP4; adipocyte protein 2/fatty acid binding protein 4; ATP5B; ATP synthase, H + transporting mitochondrial F1 complex, beta subunit; BA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet

Keywords: Acaca; acetyl-coenzyme A carboxylase alpha; Acly; ATP citrate lyase; Adrb; β-adrenergic receptor; ALT; alanine aminotransferase; Apob; apolipoprotein B; ATGL; adipose triglyceride lipase; CD; choline-deficient diet; Ces3; carboxylesterase 3; Dgat; diacyl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-α

Keywords: PPAR; peroxisome proliferator-activated receptor; LBD; ligand-binding domain; SPR; surface plasmon resonance; TR-FRET; time-resolved fluorescent resonance energy transfer; TG; triglyceride; HTG; hypertriglyceridemia; RXR; retinoid X receptor; EO; essentia

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid

Keywords: 2OHOA; 2-hydroxyoleic acid; DAG; diacylglycerol; DPH; 1,6-diphenyl-1,3,5-hexatriene; FAME; fatty acid methyl ester; HPTLC; high performance TLC; LUV; large unilamellar vesicle; MLV; multilamellar vesicle; MUFA; monounsaturated fatty acid; PC; phosphatidyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic correlation between composition of bovine milk fat in winter and summer, and DGAT1 and SCD1 by season interactions

Keywords: genetic correlation; seasonal variation; DGAT1; SCD1;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Benzimidazole-carboxamides as potent and bioavailable stearoyl-CoA desaturase (SCD1) inhibitors from ligand-based virtual screening and chemical optimization

Keywords: Benzimidazole; SCD1; SCD1 inhibition; Diabetes; Enzyme inhibition; Virtual screening

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery and pharmacological characterization of SAR707 as novel and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD1)

Keywords: Stearoyl-CoA desaturase; SCD1; Hexahydro-pyrrolopyrrole; Inhibitor; Zucker diabetic fatty rat; Fatty acid desaturation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation

Keywords: ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; ACS; acyl-CoA synthetase; AMPK; AMP-activated protein kinase; CD36; fatty acid translocase/CD36; CPT1; carnitine palmitoyltransferase 1; FA; fatty acids; NEFA; non-esterified FA; FATP1; fatty acid transp

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of SCD1- and DGAT1-genes on production traits of Chinese Holstein cows located in the Delta Region of Yangtze River

Keywords: SCD1;DGAT1; Polymorphism; Milk production trait; Chinese Holstein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation

Keywords: BMI; body mass index; CRP; C-Reactive protein; FA; fatty acids; FFQ; food frequency questionnaire; HOMA-IR; homeostasis model of assessment of insulin resistance; HWE; Hardy-Weinberg equilibrium; MAF; minor allele frequency; MUFA; monounsaturated fatty

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Alpha-linolenic acid increases cholesterol efflux in macrophage-derived foam cells by decreasing stearoyl CoA desaturase 1 expression: evidence for a farnesoid-X-receptor mechanism of action

Keywords: ALA; SCD1; FXR; SREBP1C; Cholesterol efflux; Foam cell;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase

Keywords: ASMs; acid soluble metabolites; ACSL; long-chain fatty acyl-CoA synthetase; ATGL; adipose triglyceride lipase; BSA; bovine serum albumin; CA; cell-associated; CD36/FAT; fatty acid translocase; FDR; false discovery rate; CE; cholesteryl ester; CRAT; carnit

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Expression pattern of oxidative stress and antioxidant defense-related genes in the aging Fischer 344/NHsd rat cochlea

Keywords: Age-related hearing loss; Presbycusis; Cochlea; Fischer 344; Antioxidant; Reactive oxygen species; Oxidative stress; Rat; Genes; Scd1; Dhcr24; Aass; Cygb; Duox2; Gpx3; Gpx6; Gstk1; Gsr; Nqo1; Slc38a5; Txnip; Vim;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

The effect of milk polar lipids separated from butter serum on the lipid levels in the liver and the plasma of obese-model mouse (KK-Ay)

Keywords: Milk polar lipids; Sphingomyelin; Ceramide; Lipid metabolism; SCD1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of growth performance and lipid metabolism by dietary n-3 highly unsaturated fatty acids in juvenile grass carp, Ctenopharyngodon idellus

Keywords: CF; condition factor; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; G6PDH; glucose-6-phosphate dehydrogenase; HUFAs; highly unsaturated fatty acids; IPF; intraperitoneal fat; LA; linoleic acid; LNA; linolenic acid; LPL; lipoprotein lipase; MDA; m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

High density lipoprotein inhibits the activation of sterol regulatory element-binding protein-1 in cultured cells

Keywords: HDL(-c); high density lipoprotein (-cholesterol); RCT; reverse cholesterol transport; NAFLD; non-alcoholic fatty liver disease; SRBI; scavenger receptor class BI; SREBP-1; sterol regulatory element-binding protein-1; nSREBP-1 or pSREBP-1; nuclear form or

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Effect of PUFA on embryo cryoresistance, gene expression and AMPKα phosphorylation in IVF-derived bovine embryos

Keywords: Embryo culture environment; PUFA; SCD1; FADS2; SREBP1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone

Keywords: dKO; mice homozygous for inactivating alleles of both the Pmch and Scd1 genes (Pmch−/−, Scd1−/− genotype); dWT; mice homozygous for normal alleles of both the Pmch and Scd1 genes (Pmch+/+, Scd1+/+ genotype) (=B6); pKO; “Pmch knockout” mice, wi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Medium-chain triglycerides impair lipid metabolism and induce hepatic steatosis in very long-chain acyl-CoA dehydrogenase (VLCAD)-deficient mice

Keywords: VLCADD; very-long-chain acyl-CoA dehydrogenase deficiency; VLCAD KO; very-long-chain acyl-CoA dehydrogenase knock-out; WT; wild type; LCT; long-chain triglyceride; MCT; medium-chain triglyceride; ACC-1α; acyl-CoA carboxylase; FASN; fatty acid synthase; 1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin

Keywords: SCD1; Leptin; ERK1/2; HepG2; Sp1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Thiazole analog as stearoyl-CoA desaturase 1 inhibitor

Keywords: Stearoyl-CoA desaturase 1 inhibitor; SCD1; Thiazole; MF-152; Obesity; Type-2 diabetes

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Exploring polymorphisms and effects on milk traits of the DGAT1, SCD1 and GHR genes in four cattle breeds

Keywords: SNP; DGAT1; SCD1; GHR; Milk traits; Cow

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity

Keywords: Stearoyl-CoA desaturase; SCD1; Obesity; Insulin; Carbohydrate; Lipogenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of milk fat composition, DGAT1, and SCD1 on fertility traits in Dutch Holstein cattle

Keywords: dairy cattle; milk fat composition; DGAT1; SCD1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه