Keywords: Phloridzin; Ulcerative colitis; NHE3; SGLT1; Food additive; Phlorizin (PubChem CID: 6072); Dextran hydrogen sulfate sodium salt (PubChem CID: 3084656); Mesalazine (PubChem: 4075);
مقالات ISI (ترجمه نشده)
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Keywords: SGLT2; SGLT1; Gliflozin; Type 1 diabetes; Diabetic kidney disease;
Keywords: α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
Keywords: Bee pollen; Phytometabolites; Nutrition; Therapeutic benefits; Food safety; GC-MS; gas chromatography-mass spectrometry; LC-ESI/MS; liquid chromatography-electrospray ionization mass spectrometry; TLC; thin layer chromatography; HPLC-DAD-ESI/MS; high-pe
Keywords: Ion Transport; Diarrhea; Enteric Pathogen; Epithelium; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CDI; Clostridium difficile infection; CFTR; cystic fibrosis transmembrane conductance reg
Keywords: Olive oil by-products; Polyphenols; Inflammation; Glucose metabolism; NMR based metabolomics; Foodomics; ABTS; 2,2â²-azinobis 3-ethylbenzothiazoline-6-sulfonate; AFOA; Aldehydic form of oleuropein aglycone; d6-DSS; 2,2-dimethyl-2-silapentane-d6-5-sulfo
Keywords: AMPK; 5â² adenosine monophosphate-activated protein kinase; AGE; advanced glycation end-product; BP; blood pressure; CE; cinnamon extracts; CP; cinnamon polyphenols; DM; diabetes mellitus; eNOS; endothelial nitric oxide synthase; FBG; fasting blood gluco
Keywords: AA; amino acid; ADFI; average daily feed intake; ADG; average daily gain; Ala; alanine; ANFs; anti-nutritive factors; Asn; asparagine; Asp; aspartate; CaSR; calcium sensing receptor; CCK; cholecystokinin; CD36; cluster of differentiation 36; dlM; dl-methi
Keywords: Sucralose; Glucose homeostasis; OGTT; Healthy volunteers; AUC; area under the curve; EFSA; European Food Safety Authority; HbA1C; glycated hemoglobin; GIP; gastric inhibitory peptide; GLP-1; glucagon-like peptide 1; GLUT2; apical glucose transporter type
Keywords: SGLT1; SGLT2; Phlorizin; Hippocampus; Neurodegeneration; Fluoro-Jade C; Pilocarpine; Status epilepticus;
Keywords: Intestinal Adaptation; Enteroendocrine Cells; Enterohormones; GIP; BMI; body mass index; BPL; biliopancreatic limb; [18F]-FDG; [18F]-fluorodeoxyglucose; GIP; glucose-dependent insulinotropic peptide; GLP1; glucagon-like peptide-1; GLUT; glucose transporte
Keywords: AgRP; agouti-related protein; ARC; arcuate nucleus; ASCT2; glutamine/amino acid transporter 2; B0AT1; neutral amino acid transporter 1; BBB; blood-brain barrier; CCK; cholecystokinin; CNTF; ciliary neurotrophic factor; DIO; diet-induced obesity; MCT1; m
Keywords: AE; adverse event; AUC; area under the concentration-time curve; BMI; body mass index; C150; canagliflozin 150Â mg; C300; canagliflozin 300Â mg; CI; confidence interval; CRC; clinical research center; CV; coefficient of variation; FPG; fasting plasma gluc
Keywords: Dietary fiber; Intestinal bacteria; Volatile fatty acid; Disaccharidase; Glucose transporter; ADF; acid detergent fiber; ADFI; average daily feed intake; ADG; average daily gain; ADL; acid detergent lignin; AX; arabinoxylan; CON; control diet; CP; crude p
Keywords: ANF; antinutritional factor; AUC; area under the curve; dpm; disintegrations per minute; DI; distal intestine; GLUT2; high-capacity, low affinity, bidirectional, facilitative transport protein for hexoses; Kt; transporter affinity constant; KTI; soybean K
Keywords: AQP5; Water channel; Hyperglycemia; Lens cataract; Lens transparency; GLUT1; GLUT3; Sodium-dependent glucose cotransporters; SGLT1; SGLT2;
Keywords: AA; amino acids; BLAST; basic alignment search tool; Ca; calcium; CaSR; calcium sensing receptor; ENaC; epithelial amiloride-sensitive sodium channel; GIT; gastrointestinal tract; GLU; glutamic acid; GLUT2; glucose transporter 2; Na; sodium; NaCl; sodium
Origanum majorana L. extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea
Keywords: ÎIsc; difference between the peak Isc after glucose challenge and the basal Isc; AEOM; aqueous extract of Origanum majorana L.; Atr; atropine; Bum; bumetanide; cAMP; cyclic adenosine monophosphate; CCh; Carbamylcholine chloride (Carbachol); CFTR; cystic
The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers
Keywords: AD; Decoction of processed aconite root; ALD; Decoction of processed aconite root and honey-processed liquorice; AP; Apical; BCRP; Breast cancer resistance protein; BL; Basolateral; DDAs; Diester-diterpenoid alkaloids; EIC; Extracted ion chromatogram; ER;
Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids
Keywords: GLUT2; solute carrier family 2, member 2 (SLC2A2), human; GLUT5; solute carrier family 2, member 5 (SLC2A5), human; GLUT7; solute carrier family 2, member 7 (SLC2A7), human; SGLT1; Sodium-dependent sodium-glucose cotransporter 1; EGCG; (â)-epigallocatec
Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk
Keywords: glucose tolerance; Mendelian randomization; SGLT1; BP; blood pressure; CI; confidence interval; DM; diabetes mellitus; FFQ; food frequency questionnaire; GGM; glucose-galactose malabsorption; GLP; glucagon-like peptide; HF; heart failure; HGSC; Human Geno
SGLT1 inhibition: Pros and cons
Keywords: SGLT1; SGLT2; Sotagliflozin; Canagliflozin; Glycosuria;
Black bean peptides inhibit glucose uptake in Caco-2 adenocarcinoma cells by blocking the expression and translocation pathway of glucose transporters
Keywords: Phloretin: PubChem CID: 4788; Glucose: PubChem CID: 10954115; 2-NBDG PubChem CID: 6711157; A; alanine; AMPK; 5â² adenosine monophosphate-activated protein kinase; AU; arbitrary units; BPI; bean protein isolate; E; glutamic acid; F; phenylalanine; GLUT2;
Sodium-dependent glucose transporters (SGLT) in human ischemic heart: A new potential pharmacological target
Keywords: Ischemic heart disease; Myocardial disease; Cardiac hypertrophy; Heart failure; Empagliflozin; SGLT1; SGLT2;
Dapagliflozin modulates glucagon secretion in an SGLT2-independent manner in murine alpha cells
Keywords: Alpha cells; Glucagon; SGLT1; SGLT2 inhibitors;
Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis
Keywords: Malabsorption; Glucose homeostasis; Intestinal adaptation; Microbiota; GLP-1; 2FDG; 2-deoxy-2-[18F]fluoro-d-glucose; DPP-IV; dipeptidyl-peptidase IV; GLP-1; glucagon-like peptide-1; GLUT1-7; glucose transporter 1-7; IEC; intestinal epithelial cells; IL;
Evaluation of the hypoglycemic potential of a black bean hydrolyzed protein isolate and its pure peptides using in silico, in vitro and in vivo approaches
Keywords: Black bean; Hydrolyzed protein isolate; Diabetes; Glucose absorption; Glucose transporters; Hyperglycemic rats; Glibenclamide: PubChem CID: 3488.; Glucose: PubChem CID: 10954115.; Metformin: PubChem CID: 4091.; Phloretin: PubChem CID: 4788.; Streptozotoci
Vitamin A deficiency suppresses high fructose-induced triglyceride synthesis and elevates resolvin D1 levels
Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HFSC; high fructose corn syrup; ALT; alanine aminotransferase; AST; aspartate aminotransferase; RBP4; retinol binding protein 4; FGF21; fibroblast growth factor 21; CRP; C-reac
Inhibition of SGLT1 abrogates preconditioning-induced cardioprotection against ischemia-reperfusion injury
Keywords: Preconditioning; Ischemia-reperfusion injury; Oxidative stress; SGLT1; Phlorizin;
Extracts and flavonoids from onion inhibit the intestinal sodium-coupled glucose transporter 1 (SGLT1) in vitro but show no anti-hyperglycaemic effects in vivo in normoglycaemic mice and human volunteers
Keywords: ANOVA; analysis of variances; iAUC; incremental area under the curve; GLUT2; glucose transporter 2; IGT; impaired glucose tolerance; BW; body weight; Q4â²glc; quercetin-4â²-O-glucoside; Q3,4â²diglc; quercetin-3,4â²-O-diglucoside; HPLC-DAD/ESI-MS2;
An essential role of cAMP response element-binding protein in epidermal growth factor-mediated induction of sodium/glucose cotransporter 1 gene expression and intestinal glucose uptake
Keywords: SGLT1; Sodium/glucose cotransporter 1; EGF; Epidermal growth factor; CRE; cAMP response element; GLUTs; Facilitative glucose transporters; SGLTs; Sodium-dependent glucose transporters; IECs; Intestinal epithelial cells; EGFRs; EGF receptors; RTK; Receptor
LX4211 Therapy Reduces Postprandial Glucose Levels in Patients With Type 2 Diabetes Mellitus and Renal Impairment Despite Low Urinary Glucose Excretion
Keywords: fasting plasma glucose; LX4211; pharmacokinetics; postprandial glucose; renal impairment; SGLT1; SGLT2; urinary glucose excretion;
Translating Molecular Physiology of Intestinal Transport Into Pharmacologic Treatment of Diarrhea: Stimulation of Na+ Absorption
Keywords: Diarrhea; Na Absorption; Intestine; BB; brush border; CaSR; calcium-sensing receptor; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; DRA; down-regulated in adenoma; ENaC; epithelial Na+ channel; GI; gastrointestinal; NHE3; sod
Regulation of sodium glucose co-transporter SGLT1 through altered glycosylation in the intestinal epithelial cells
Keywords: cNO; L-NAME; SGLT1; Protein kinase G; cGMP;
The Transport and Efflux of Glycosylated Luteinising Hormone-Releasing Hormone Analogues in Caco-2 Cell Model: Contributions of Glucose Transporters and Efflux Systems
Keywords: LHRH; SGLT1; GLUT2; transport; Caco-2 cell; peptides; MRP2; P-glycoprotein; glycosylation; efflux pumps;
trans-Resveratrol and ε-viniferin decrease glucose absorption in porcine jejunum and ileum in vitro
Keywords: trans-Resveratrol; ε-Viniferin; Ileum; Jejunum; SGLT1;
TNFα regulates sugar transporters in the human intestinal epithelial cell line Caco-2
Keywords: Caco-2 cells; TNF-α; GLUT5; SGLT1; PKC;
Lack of functionally active sweet taste receptors in the jejunum in vivo in the rat
Keywords: Glucose absorption; Sweet taste receptors; SGLT1; GLUT2; Acesulfame potassium; U73122; Apical translocation
Design, synthesis, and structure–activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)
Keywords: Diabetes; Postprandial hyperglycemia; SGLT1; SGLT1 inhibitor
Effects of LX4211, a Dual Sodium-Dependent Glucose Cotransporters 1 and 2 Inhibitor, on Postprandial Glucose, Insulin, Glucagon-like Peptide 1, and Peptide Tyrosine Tyrosine in a Dose-Timing Study in Healthy Subjects
Keywords: Diabetes; GLP-1; SGLT1; SGLT2; PYY; urinary glucose excretion;
Effects of LX4211, a Dual SGLT1/SGLT2 Inhibitor, Plus Sitagliptin on Postprandial Active GLP-1 and Glycemic Control in Type 2 Diabetes
Keywords: adult; diabetes; dipeptidyl peptidase-4; GIP; GLP-1; glucose; glycemic control; human; insulin; PYY; SGLT1; SGLT2; sitagliptin; urinary glucose excretion;
Addition of NMDA-receptor antagonist MK801 during oxygen/glucose deprivation moderately attenuates the upregulation of glucose uptake after subsequent reoxygenation in brain endothelial cells
Keywords: Blood-brain barrier; MK801; NMDAR; Stroke; glut1; sglt1;
Segmental diversity of electrogenic glucose transport characteristics in the small intestines of weaned pigs
Keywords: Brush-border membrane vesicles; Glucose absorption; Phlorizin; Pig; SGLT1; Small intestine; Ussing chamber
Translational Approaches for Pharmacotherapy Development for Acute Diarrhea
Keywords: AQP; aquaporins; CaCC; calcium-activated Clâ channels; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CaSR; calcium-sensing receptor; CFTR; cystic fibrosis transmembrane conductance regulator; cGMP; guanosine 3â²,5â²-cyclic monophosphate; DRA; down-r
The regulation of cancer cell death and metabolism by extracellular matrix attachment
Keywords: ECM; extra cellular matrix; ROS; reactive oxygen species; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; PDH; pyruvate dehydrogenase; PDK4; pyruvate dehydrogenase kinase 4; ANGPTL4; angiopoietin-like 4; PK; pyruvate kinase; TIGAR; TP53-induced g
Influence of age and Enterococcus faecium NCIMB 10415 on development of small intestinal digestive physiology in piglets
Keywords: ADFI; average daily feed intake; ADG; average daily gain; APN; aminopeptidase-N; BBM; brush border membranes; CASP3; caspase-3; CIAD; Coefficient of ileal apparent digestibility; CTTAD; Coefficient of total tract apparent digestibility; CON; control group
Structure-activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia
Keywords: Diabetes; Postprandial hyperglycemia; SGLT1; SGLT1 inhibitor;
New insights into urea and glucose handling by the kidney, and the urine concentrating mechanism
Keywords: active secretion; glucose transport; lactate; renal medulla; SGLT1; urea transport;
Absence of Evidence of Translocation of GLUT2 to the Apical Membrane of Enterocytes in Everted Intestinal Sleeves
Keywords: SGLT1; GLUT2; hexose transport; glucose uptake; intestinal absorption; protein kinase C
Stimulation of Na+/K+ ATPase activity and Na+ coupled glucose transport by β-catenin
Keywords: Glucose transport; Na+-pump; Ouabain; SGLT1; Actinomycin D; Cell membrane