دانلود مقالات ISI درباره مبدل سیگنال و فعال کننده رونویسی + ترجمه فارسی

The TH1 phenotype of follicular helper T cells indicates an IFN-γ-associated immune dysregulation in patients with CD21low common variable immunodeficiency

Keywords: مبدل سیگنال و فعال کننده رونویسی; Follicular helper T cells; common variable immunodeficiency; IFN-γ; germinal center; CD21low B cells; T-bet; CT; Computed tomography; cTFH; Circulating follicular T helper; CVID; Common variable immunodeficiency; CVIDc; Complex common variable immunodefi

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target

Keywords: مبدل سیگنال و فعال کننده رونویسی; Aak2; 5′AMP-activated protein kinase catalytic subunit alpha-2; ACC; acetyl CoA carboxylase; Acly; ATP citrate lyase; Adipo-IR; adipose tissue insulin resistance index; ADME; absorption, distribution, metabolism, excretion; AGA; appropriate-for-gestatio

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Keywords: مبدل سیگنال و فعال کننده رونویسی; Interleukin-4; STAT6; Retinoid X receptor; Macrophage; Chromatin immunoprecipitation; Trancriptome; Cistrome; JAK; Janus tyrosine kinases; STAT; Signal Transducer and Activator of Transcription; IL-4; Interleukin 4; TNFα; tumor necrosis factor alpha; IFN

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses

Keywords: مبدل سیگنال و فعال کننده رونویسی; ALS; amyotrophic lateral sclerosis; BMDM; bone marrow-derived macrophages; C9orf72; chromosome 9 open-reading frame 72; CNS; central nervous system; CXCL; CXC chemokine ligand; DAMPs; damage-associated molecular patterns; DMEM; Dulbecco's Modified Eagle

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Downregulation of estrogen-related receptor alpha inhibits human cutaneous squamous cell carcinoma cell proliferation and migration by regulating EMT via fibronectin and STAT3 signaling pathways

Keywords: مبدل سیگنال و فعال کننده رونویسی; Cutaneous squamous cell carcinoma; Estrogen-related receptor alpha; Epithelial mesenchymal transition; Signal transducer and activator of transcription; Fibronectin;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Activated plasmacytoid dendritic cells regulate type 2 innate lymphoid cell-mediated airway hyperreactivity

Keywords: مبدل سیگنال و فعال کننده رونویسی; Type 2 innate lymphoid cells; asthma; plasmacytoid dendritic cells; eosinophilic airway inflammation; immune regulation; AHR; Airway hyperreactivity; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; DT; Diphtheria toxin; DTR; Diphtheria toxin receptor;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of new benzensulfonamide derivatives as tripedal STAT3 inhibitors

Keywords: مبدل سیگنال و فعال کننده رونویسی; Antitumor activity; Sulfonamide; Selectivity; Structure-based drug design; STAT3 phosphorylation; Apoptosis; DMSO; dimethyl sulfoxide; Erk; extracellular regulated kinase; rt; room temperature; MTT; 3-4, 5-dehyl-al-2-y]-2, 5-dphnetrazolium bromide; SH2;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Clinical variables and ethnicity may influenced by polymorphism of CAT −262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications

Keywords: مبدل سیگنال و فعال کننده رونویسی; T1D; type1 diabetes; CAT; Catalase; MnSOD; manganese superoxide dismutase; SOD; superoxide dismutase; WHO; World Health Organization; TAHINA; survey Transition And Health Impact in North Africa; INSP; National Institute of Public Health; ROS; Reactive oxy

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3: The art of multi-tasking of metabolic and immune functions in obesity

Keywords: مبدل سیگنال و فعال کننده رونویسی; Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation

Keywords: مبدل سیگنال و فعال کننده رونویسی; Interferon regulatory factor 8; immunodeficiency; dendritic cell; monocyte; myeloproliferation; interferon; AICE; Activator protein 1-interferon regulatory factor composite element; BAL; Bronchoalveolar lavage; cDC; Conventional dendritic cell; CDR3; Co

دانلود رایگان متن کامل مقاله ISI 66 صفحه سال انتشار : 2018 سفارش ترجمه

The role of TAM family receptors and ligands in the nervous system: From development to pathobiology

Keywords: مبدل سیگنال و فعال کننده رونویسی; ACSF; artificial cerebral spinal fluid; APP; amyloid precursor protein; BBB; blood-brain-barrier; BCECs; brain capillary endothelial cells; C57Bl6/J; strain of mice for MOG-induce EAE and cuprizone studies; CNS; central nervous system; DKO; Gas6−/−Axl

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis

Keywords: مبدل سیگنال و فعال کننده رونویسی; Atopic dermatitis; psoriasis; transdermal delivery peptide; protein tyrosine phosphatase; T-cell protein tyrosine phosphatase; transcutaneous drug; immunomodulatory protein; AD; Atopic dermatitis; AP; Astrotactin 1-derived peptide; CHS; Contact hypersen

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphatase wild-type p53-induced phosphatase 1 controls the development of TH9 cells and allergic airway inflammation

Keywords: مبدل سیگنال و فعال کننده رونویسی; Allergy; Wip1; TH9 cell development; IL-9; phosphatase; AP-1; Activator protein 1; BAL; Bronchoalveolar lavage; BATF; Basic leucine zipper ATF-like transcription factor; ChIP; Chromatin immunoprecipitation; dLN; Draining lymph node; Foxp3; Forkhead box pr

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

Zinc chelation decreases IFN-β-induced STAT1 upregulation and iNOS expression in RAW 264.7 macrophages

Keywords: مبدل سیگنال و فعال کننده رونویسی; zinc; macrophage; signal transducer and activator of transcription; STAT1; inducible nitric monoxide synthase; iNOS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Hypoxia-induced activation of specific members of the NF-kB family and its relevance to pulmonary vascular remodeling

Keywords: مبدل سیگنال و فعال کننده رونویسی; pH; pulmonary hypertension; SMC; human pulmonary artery smooth muscle cells; EC; human pulmonary microvascular endothelial cells HPMECSt1.6R; NF-kB; nuclear factor kappa-light-chain-enhancer of activated B cells; RelA; v-rel avian reticuloendotheliosis vi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

High fat diet-induced obesity increases myocardial injury and alters cardiac STAT3 signaling in mice after polymicrobial sepsis

Keywords: مبدل سیگنال و فعال کننده رونویسی; CLP; cecal ligation and puncture; cTnI; cardiac troponin; STAT; signal transducer and activator of transcription; SOCS3; suppressor of the cytokine signaling family; Sepsis; Obesity; STAT3; Cardiac inflammation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of luteolin on inflammatory responses in RAW264.7 macrophages activated with LPS and IFN-γ

Keywords: مبدل سیگنال و فعال کننده رونویسی; LPS; lipopolysaccharide; IFN-γ; interferon-γ; iNOS; inducible nitric oxide synthase; IL-1β; interleukin-1β; CD; cluster of differentiation; TNF; tumour necrosis factor; STAT; signal transducer and activator of transcription; HPLC; high performance liq

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of non-lethal West Nile Virus (WNV) infection in horses: Subclinical pathology and innate immune response

Keywords: مبدل سیگنال و فعال کننده رونویسی; Flavivirus; Arbovirus; Equine; Interferons; Innate immune response; CNS; central nervous system; CXCL10; chemokine (C-X-C motif) ligand 10; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HE; hematoxylin and eosin; HIF-1α; hypoxia inducible factor 1α; IF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The good and the bad faces of STAT1 in solid tumours

Keywords: مبدل سیگنال و فعال کننده رونویسی; BAD; Bcl2-associated agonist of cell death; Bcl; B-cell lymphoma; CD; cluster of differentiation; CDK; cyclin-dependent kinase; CTL; cytotoxic T lymphocyte; CUG; cancer upregulated gene; CXCL; C-X-C motive ligand; DC; dendritic cells; DAMP; danger-associa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The evolutionary divergence of STAT transcription factor in different Anopheles species

Keywords: مبدل سیگنال و فعال کننده رونویسی; STAT; Signal Transducer and Activator of Transcription; JAK; Janus kinase; NJ; Neighbor-Joining; An.; Anopheles; MEGA; Molecular Evolutionary Genetics Analysis; UTR; untranslated region; MYA; million years ago; P. berghei; Plasmodium berghei; SOCS; suppre

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Carp Il10a and Il10b exert identical biological activities in vitro, but are differentially regulated in vivo

Keywords: مبدل سیگنال و فعال کننده رونویسی; Interleukin-10; Teleost; Paralogues; Gene duplication; APCs; antigen presenting cells; RTqPCR; real-time quantitative PCR; CTL; cytotoxic T lymphocyte; Socs3; suppressor of cytokine signaling 3; AP-1; activator protein-1; AP1R; MAF and AP1 related factors

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Therapeutic effect of Cryptotanshinone on experimental rheumatoid arthritis through downregulating p300 mediated-STAT3 acetylation

Keywords: مبدل سیگنال و فعال کننده رونویسی; RA; rheumatoid arthritis; CTS; Cryptotanshinone; DMARDs; disease-modifying anti-rheumatic drugs; FLS; fibroblast-like synoviocytes; CIA; type-II collagen-induced arthritis; STAT; Signal transducer and activator of transcription; IGU; iguratimod; Treg; reg

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Liver immunology: How to reconcile tolerance with autoimmunity

Keywords: مبدل سیگنال و فعال کننده رونویسی; PPR; pattern recognition receptor; HBV; hepatitis B virus; HCV; hepatitis C virus; TLR; toll-like receptor; IFN; interferon; LSEC; liver sinusoidal endothelial cell; APC; antigen presenting cell; MHC; major histocompatibility complex; PDL-1; program death

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The role of interleukin-17A in the pathogenesis of kidney diseases

Keywords: مبدل سیگنال و فعال کننده رونویسی; Interleukin-17A; inflammation; kidney disease; AHR; aryl hydrocarbon receptor; AKI; acute kidney injury; ANCA; antineutrophil cytoplasmic antibody; APOE; apolipoprotein E; ASC; apoptosis-associated speck-like protein containing a carboxy-terminal CARD; Ct

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa

Keywords: مبدل سیگنال و فعال کننده رونویسی; CMV; cytomegalovirus; HCV; hepatitis C virus; IFNα; interferon alpha; JAK; Janus kinase; PBMC; peripheral blood mononuclear cells; PDCs; plasmacytoid dendritic cells; RA; rheumatoid arthritis; RASFs; rheumatoid arthritis synovial fibroblasts; SLE; system

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans

Keywords: مبدل سیگنال و فعال کننده رونویسی; Tumor Suppressor; Epigenetics; Stomach Cancer; Trefoil Factor 2; 5′-Aza-C; 5′-aza-2′-deoxycytidine; AB/PAS; alcian blue periodic acid-Schiff; Erk; extracellular signal-regulated kinase; IFN; interferon; IL; interleukin; IM; intestinal metaplasia; MN

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib

Keywords: مبدل سیگنال و فعال کننده رونویسی; HES; hypereosinophilic syndrome; JAK; Janus kinase; L-HES; lymphocytic variant HES; STAT; signal transducer and activator of transcription; Th2; T helper type 2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2

Keywords: مبدل سیگنال و فعال کننده رونویسی; Severe asthma; corticosteroids; airway hyperresponsiveness; miR-21; PI3 kinase; histone deacetylase 2; Chlamydia species; Haemophilus influenzae; influenza; respiratory syncytial virus; AAD; Allergic airway disease; AHR; Airway hyperresponsiveness; Ant-21

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation

Keywords: مبدل سیگنال و فعال کننده رونویسی; STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex

Keywords: مبدل سیگنال و فعال کننده رونویسی; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SOCS; suppressor of cytokine signaling; TYK2; tyrosine kinase 2; NF-κB; nuclear factor kappa B; C/EBP; CCAAT-enhancer-binding proteins; GATA-1; GATA-binding factor 1; AP-1; Activa

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation

Keywords: مبدل سیگنال و فعال کننده رونویسی; HCC; Tumor Progression; Benign; SHH; bex7,8HCA; β-catenin mutated hepatocellular adenoma in exon 7 or 8; bex7,8IHCA; β-catenin mutated inflammatory hepatocellular adenoma in exon 7 or 8; bex3IHCA; β-catenin mutated inflammatory hepatocellular adenoma i

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

AHR in the skin: From the mediator of chloracne to a therapeutic panacea?

Keywords: مبدل سیگنال و فعال کننده رونویسی; Arylhydrocarbon receptor; Skin; Inflammation; Dietary ligands; Air pollution; AHR; aryl hydrocarbon receptor; AHRR; AHR-repressor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; IDO; indoleamin-2,3,-dioxygenase; NFκB; nuclear factor κB; DC; dendritic cell;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and Wnts to Promote Regeneration

Keywords: مبدل سیگنال و فعال کننده رونویسی; dsRNA; double-stranded RNA; HPGD; 15-hydroxyprostaglandin dehydrogenase; NHEK; normal human epidermal keratinocyte; PGE2; prostaglandin E2; poly(I:C); polyinosinic:polycytidylic acid; PTGS; prostaglandin-endoperoxide synthase 2; PWD; post-wounding day; si

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

High-throughput thermofluor-based assays for inhibitor screening of STAT SH2 domains

Keywords: مبدل سیگنال و فعال کننده رونویسی; EMSA; electrophoretic mobility shift assays; FP; fluorescence polarization; HRP; Horseradish peroxidase; IPTG; isopropyl β-d-1-thiogalactopyranoside; IMAC; immobilized metal ion affinity chromatography; LB; Lysogeny broth; NTA; nitrilotriacetic acid; PVD

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Transcriptome profiling and expression analysis of immune responsive genes in the liver of Golden mahseer (Tor putitora) challenged with Aeromonas hydrophila

Keywords: مبدل سیگنال و فعال کننده رونویسی; Immune response; Bacterial challenge; Transcriptome sequencing; Differential gene expression; Complement system; Tissue specific expression; qPCR expression; DGE; Differential gene expression; FDR; False discovery rate; GO; gene ontology; HSP; Heat shock

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease

Keywords: مبدل سیگنال و فعال کننده رونویسی; K; keratin; PMEL; premelanosome protein-specific transgenic T cell; STAT; signal transducer and activator of transcription;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of JAK-STAT signaling pathway genes and their microRNAs in the intestinal mucosa of genetically disparate chicken lines induced with necrotic enteritis

Keywords: مبدل سیگنال و فعال کننده رونویسی; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SOCS; suppressor of cytokine signaling; IL; interleukin; RT; reverse transcription; TYK2; tyrosine kinase 2; SH2 (PTPN); src homology 2-containing tyrosine phosphatase 2; PIAS; pro

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Nickel Sulfate Promotes IL-17A Producing CD4+ T Cells by an IL-23-Dependent Mechanism Regulated by TLR4 and Jak-STAT Pathways

Keywords: مبدل سیگنال و فعال کننده رونویسی; Ab; antibody; ACD; allergic contact dermatitis; DC; dendritic cell; MoDC; monocyte-derived dendritic cell; MAPK; mitogen-activated protein kinase; NFIL-3; nuclear factor, interleukin 3 regulated; NiSO4; nickel sulfate; STAT; signal transducer and activato

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

IRF2-INPP4B axis participates in the development of acute myeloid leukemia by regulating cell growth and survival

Keywords: مبدل سیگنال و فعال کننده رونویسی; AML; acute myeloid leukemia; IRF2; interferon-regulatory factor 2; INPP4B; inositol polyphosphate-4-phosphatase, type-II; STAT; signal transducer and activator of transcription; Acute myeloid leukemia; IRF2; INPP4B; Growth; Survival;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells

Keywords: مبدل سیگنال و فعال کننده رونویسی; AEBSF; 4-(2-aminoethyl)-benzolsulfonylfluorid; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; Epo; erythropoietin; EpoR; erythropoietin receptor; Erk; extracellular signal regulated kinase; FCS; fetal calf serum; Gab1; G

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2

Keywords: مبدل سیگنال و فعال کننده رونویسی; HCC; Hepatocellular carcinoma; TNFα; tumor necrosis factor α; LPS; lipopolysaccharide; PMA; phorbol myristate acetate; UV; virus and ultraviolet; TF; transcription factor; NF-κB; nuclear factor κB; HBV; hepatitis B virus; HCV; hepatitis C virus; DTGs;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Oxidized phospholipids exert a dual effect on bile acid-induced CCL2 expression in pancreatic acini

Keywords: مبدل سیگنال و فعال کننده رونویسی; Inflammatory gene expression; Pancreatic acinar cells; PPARγ; Oxidized phospholipids; TLR4; CCL2; chemokine (C-C motif) ligand 2; FA; fatty acid; JAK; janus kinase; JNK-MAPK; c-Jun NH2-terminal kinase mitogen-activated protein kinase; NF-κB; nuclear fac

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: Putative mechanisms through PPAR activation

Keywords: مبدل سیگنال و فعال کننده رونویسی; AP-1; activator protein 1; B94, TNFAIP2; TNF alpha induced protein 2; C/EBP; CCAAT-enhancer-binding protein; CCL; chemokine ligand; CEX-1; chemokine exodus protein 1; COX; cyclooxygenase; CXCL; chemokine (C-X-C motif) ligand; CYP; cytochrome P450 monooxyg

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Antagonizing STAT3 activation with benzo[b]thiophene 1, 1-dioxide based small molecules

Keywords: مبدل سیگنال و فعال کننده رونویسی; Antitumor agents; Aminobenzo[b]thiophene 1, 1-dioxides; Drug-likeness properties; STAT3 phosphorylation, Apoptosis; DMSO; dimethyl sulfoxide; AKT; a serine/threonine protein kinase; Erk; extracellular regulated kinase; rt; room temperature; MTT; 3-4,5-deh

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis

Keywords: مبدل سیگنال و فعال کننده رونویسی; cRac1; Cellular Rac1; CRIB; Cdc42/Rac-interactive binding; E-cadherin; Epithelial cadherin; ECL; enhanced chemiluminescence; EGF; Epidermal growth factor; GAP; GTPase activating protein; GDP; guanosine 5′-diphosphate; GEF; guanine nucleotide exchange fa

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanism of TH2/TH17-predominant and neutrophilic TH2/TH17-low subtypes of asthma

Keywords: مبدل سیگنال و فعال کننده رونویسی; Asthma endotype; TH2/TH17-predominant asthma; neutrophilic asthma; IL-1; C3a; infection; BAL; Bronchoalveolar lavage; DAMP; Danger-associated molecular pattern; G-CSF; Granulocyte colony-stimulating factor; IL-1R; IL-1 receptor; MAPK; Mitogen-activated pr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 and Reduces Colitis in Mice

Keywords: مبدل سیگنال و فعال کننده رونویسی; Mouse Model; Gene Regulation; DNA Cleavage; Immune Response; CD; Crohn's disease; IBD; inflammatory bowel disease; IFN; interferon; IL; interleukin; mRNA; messenger RNA; STAT; signal transducer and activator of transcription; TNF; tumor necrosis factor;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications

Keywords: مبدل سیگنال و فعال کننده رونویسی; AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Β1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

Keywords: مبدل سیگنال و فعال کننده رونویسی; Aβ42; β-amyloid42; ABCA1; ATP-Binding Cassette Transporter A1; AD; Alzheimers disease; ADAM; AD-related disintegrin and metalloprotease; AICD; APP- intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoE; ApolipoproteinE;

دانلود رایگان متن کامل مقاله ISI 175 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of poly(rC) binding protein 2 (PCBP2) as a target protein of immunosuppressive agent 15-deoxyspergualin

Keywords: مبدل سیگنال و فعال کننده رونویسی; 15-Deoxyspergualin; Biotin conjugate; Target protein; Poly(rC) binding protein 2 (PCBP2); Signal transducer and activator of transcription (STAT); DSG; 15-deoxyspergualin; BDSG; biotinylated derivative of DSG; PCBP2; poly(rC) binding protein 2; STAT; sign

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه