دانلود مقالات ISI درباره مبدل سیگنال و فعال کننده رونویسی + ترجمه فارسی

Therapeutics targeting innate immune/inflammatory responses through the interleukin-6/JAK/STAT signal transduction pathway in patients with cancer

Keywords: مبدل سیگنال و فعال کننده رونویسی; JAK; Janus Activated Kinase; STAT; Signal Transducer and Activator of Transcription; EGF; epidermal growth factor; TGF-B; transforming growth factor beta; VEGF; vascular endothelial growth factor; TNF-a; tumour necrosis factor alpha; CRP; C-reactive prote

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

cAMP/PKA enhances interleukin-1β-induced interleukin-6 synthesis through STAT3 in glial cells

Keywords: مبدل سیگنال و فعال کننده رونویسی; 8-bromo cAMP; adenosine-3′,5′-cyclic monophosphate, 8-bromo-, sodium salt; CMI; 4-cyano-3-methylisoquinoline; CNS; central nervous system; DMEM; Dulbecco's modified Eagle's medium; EPAC; exchange proteins directly activated by cAMP; ELISA; enzyme-link

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial STAT3: Powering up a potent factor

Keywords: مبدل سیگنال و فعال کننده رونویسی; EGF; epidermal growth factor; ETC; Electron Transport Chain; GAS; γ-activated sequence; IκB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; JAK; Janus Kinase; LIF; leukemia inhibitory factor; NF-κB; nuclear factor kappa-l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264.7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO-1 pathways

Keywords: مبدل سیگنال و فعال کننده رونویسی; SG; Sophoraflavanone G; LPS; lipopolysaccharide; NO; nitric oxide; PGE2; prostaglandin E2; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; IL-1β; interleukin-1β; PI3K; phosphoinositi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

CD4+ B220+ TCRγδ+ T cells produce IL-17 in lupus-prone MRL/lpr mice

Keywords: مبدل سیگنال و فعال کننده رونویسی; SLE; systemic lupus erythematosus; RORγt; retinoid-related orphan receptor γt; STAT; signal transducer and activator of transcription; Systemic lupus erythematosus; IL-17; γδT cells;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression

Keywords: مبدل سیگنال و فعال کننده رونویسی; AI; anemia of inflammation; BMP; bone morphogenetic protein; ERK; extracellular signal-regulated kinase; ESAs; erythropoiesis-stimulating agents; HAMP; hepcidin antimicrobial peptide; HJV; hemojuvelin; IL-6; interleukin-6; JAK; Janus kinase; LPS; lipopoly

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Soluble receptor for advanced glycation end-products protects against ischemia/reperfusion-induced myocardial apoptosis via regulating the ubiquitin proteasome system

Keywords: مبدل سیگنال و فعال کننده رونویسی; sRAGE; soluble receptor for advanced glycation end-products; I/R; Ischemia/Reperfusion; UPS; Ubiquitin proteasome system; LAD; Left anterior descending coronary artery; STAT; Signal transducer and activator of transcription; RAGE; Receptor for advanced gl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Non-CSCs nourish CSCs through interleukin-17E-mediated activation of NF-κB and JAK/STAT3 signaling in human hepatocellular carcinoma

Keywords: مبدل سیگنال و فعال کننده رونویسی; Cancer stem cell; Non-cancer stem cell; IL-17E; IL-17RB; Human hepatocellular carcinoma; CSCs; cancer stem cells; non-CSCs; non- cancer stem cells; IL; interleukin; GFP; green fluorescent protein; HCC; hepatocellular carcinoma; JAK; Janus kinases; STAT; s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The ubiquitin-like modifier FAT10 in cancer development

Keywords: مبدل سیگنال و فعال کننده رونویسی; AIPL1; aryl-hydrocarbon receptor like-1; APC/C; anaphase-promoting complex/cyclosome; DUB; deubiquitylating enzyme; EMT; epithelial-mesenchymal transition; FAT10; HLA-F adjacent transcript 10; GSK; glycogen synthase kinase; HCC; hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

IL-1 receptor antagonist (IL-1Ra)-Fc ameliorate autoimmune arthritis by regulation of the Th17 cells/Treg balance and arthrogenic cytokine activation

Keywords: مبدل سیگنال و فعال کننده رونویسی; ACR; American College of Rheumatology; APC; allophycocyanin; CD; cluster of differentiation; CIA; collagen induced arthritis; CII; type II collagen; CTLA-4; cytotoxic T-lymphocyte antigen 4; DMARD; disease-modifying antirheumatic drug; ELISA; enzyme-linke

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

JAK1/2 Inhibitor Ruxolitinib Controls a Case of Chilblain Lupus Erythematosus

Keywords: مبدل سیگنال و فعال کننده رونویسی; JAK; Janus kinase; LE; lupus erythematosus; MF; myelofibrosis; STAT; signal transducer and activator of transcription;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Lck/PLCγ control migration and proliferation of interleukin (IL)-2-stimulated T cells via the Rac1 GTPase/glycogen phosphorylase pathway

Keywords: مبدل سیگنال و فعال کننده رونویسی; PYGM; glycogen phosphorylase muscle isoform; Lck; lymphocyte-specific protein tyrosine kinase; PLCγ; phospholipase; PI3K; phosphatidylinositide 3-kinase; AKs; Janus kinases; STAT; signal transducer and activator of transcription; GEF; Guanine Nucleotide

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Regulatory T cells in allergic diseases

Keywords: مبدل سیگنال و فعال کننده رونویسی; Asthma; food allergy; regulatory T cells; forkhead box P3; IL-4; TH2 cells; CNS; Conserved noncoding region; CTLA-4; Cytotoxic T-lymphocyte-associated protein 4; DC; Dendritic cell; FOXP3; Forkhead box P3; GF; Germ-free; ICOS; Inducible T cell costimulat

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Fifty years later: Emerging functions of IgE antibodies in host defense, immune regulation, and allergic diseases

Keywords: مبدل سیگنال و فعال کننده رونویسی; IgE; mast cells; anaphylaxis; ADAM; A disintegrin and metalloproteinase; AID; Activation-induced cytidine deaminase; APC; Antigen-presenting cell; BAFF; B cell-activating factor of the TNF family; CSR; Class-switch recombination; DC; Dendritic cell; DS

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation

Keywords: مبدل سیگنال و فعال کننده رونویسی; YAP1; Yes; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; eIF4E; eukaryotic translation initiation factor 4E; PI3K; phosphatidylinositide-3-kinase; WNT; Wingless-type mouse mammary tumor virus integration site family m

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Common variable immunodeficiency, impaired neurological development and reduced numbers of T regulatory cells in a 10-year-old boy with a STAT1 gain-of-function mutation

Keywords: مبدل سیگنال و فعال کننده رونویسی; CMC; chronic mucocutaneous candidiasis; CVID; common variable immunodeficiency; FOXP3; forkhead-box protein 3; GOF; gain-of-function; STAT; signal transducer and activator of transcription; Immunodeficiency; STAT transcription factor; Cytokine signaling;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

IFN-β differentially regulates the function of T cell subsets in MS and EAE

Keywords: مبدل سیگنال و فعال کننده رونویسی; APC; antigen-presenting cell; BBB; blood-brain barrier; CCR; C-C chemokine receptor; CNS; central nervous system; CSF; cerebrospinal fluid; CXCR; C-X-C chemokine receptor; EAE; experimental autoimmune encephalomyelitis; FoxA; forkhead box protein A; FOXP3

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Epidermal Mineralocorticoid Receptor Plays Beneficial and Adverse Effects in Skin and Mediates Glucocorticoid Responses

Keywords: مبدل سیگنال و فعال کننده رونویسی; CO; control; Dex; dexamethasone; GC; glucocorticoid; GR; GC receptor; GREKO; GR epidermal knockout; GRE; glucocorticoid response element; HA; hemagglutinin; MR; mineralocorticoid receptor; MREKO; MR epidermal knockout; PMA; phorbol 12-myristate 13-acetate

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome

Keywords: مبدل سیگنال و فعال کننده رونویسی; CARD; capsase recruitment domain; CNV; copy number variation; CTCL; cutaneous T-cell lymphoma; kb; kilobase; Mb; megabase; MF; mycosis fungoides; RAG; recombination activating gene; SNV; single nucleotide variant; SS; Sézary syndrome; STAT; signal transd

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Immunomodulatory Activities of the Benzoxathiole Derivative BOT-4-One Ameliorate Pathogenic Skin Inflammation in Mice

Keywords: مبدل سیگنال و فعال کننده رونویسی; AD; atopic dermatitis; BOT-4-one; 2-cyclohexylimino-6-methyl-6,7-dihydro-5H-benzo[1,3]oxathiol-4-one; FoxP3; forkhead box P3; GATA-3; GATA binding protein 3; IKK; IκB kinase; LPS; lipopolysaccharide; NPT; neomycin phosphotransferase; RORγt; retinoic aci

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Improvement of Sclerodermatous Graft-Versus-Host Disease in Mice by Niclosamide

Keywords: مبدل سیگنال و فعال کننده رونویسی; Ab; antibody; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; ALT; Alanine aminotransferase; AU; arbitrary unit; cGVHD; chronic GVHD; eGFP; enhanced green fluorescent protein; ERK; extracellular signal-regulated kinase; GVHD; graft-ve

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-Inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T Lymphocytes

Keywords: مبدل سیگنال و فعال کننده رونویسی; ACD; allergic contact dermatitis; CCCP; carbonyl cyanide m-chlorophenylhydrazone; ConA; concanavalin A; CQ; chloroquine; CsA; cyclosporine A; LC3; microtubule-associated protein 1 light chain 3; p27kip; cyclin-dependent kinase inhibitor p27; p-AKT; phosph

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis

Keywords: مبدل سیگنال و فعال کننده رونویسی; 2-AG; 2-arachidonoylglycerol; AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; ARC; hypothalamic arcuate nucleus; CRH; corticotropin-releasing hormone; DSI; depolarization-induced suppression of inhibition; ERK; extracellular signal-regul

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication

Keywords: مبدل سیگنال و فعال کننده رونویسی; TLR3; HIV; Viral transactivation; LTR; NFκB; JNK; STAT1; Histone acetylation; Epigenetics; Human monocyte-derived macrophages; TZM-bl; U38 cells; AP-1; activator protein-1; B2M; beta-2-microglobulin; BCA; bicinchoninic acid; CAT; chloramphenicol acetyltr

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2016 سفارش ترجمه

Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans

Keywords: مبدل سیگنال و فعال کننده رونویسی; Sleep; Inflammation; Immunology; Sleep deprivation; Interleukin-6; Tumor necrosis factor-α; Signal transducer and activator of transcription; Flow cytometry; Humans; Monocytes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

C-mannosylation of thrombopoietin receptor (c-Mpl) regulates thrombopoietin-dependent JAK-STAT signaling

Keywords: مبدل سیگنال و فعال کننده رونویسی; Post-translational modification; C-mannosylation; Thrombopoietin receptor; c-Mpl; JAK-STAT; TPO; thrombopoietin; JAK; Janus kinase; STAT; signal transducer and activator of transcription; ECD; extracellular domain;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway

Keywords: مبدل سیگنال و فعال کننده رونویسی; NO2; nitrogen dioxide; MUC5AC; mucin gene; IL-1β; Interleukin-1β; IL-6; Interleukin-6; ICAM-1; intercellular adhesion molecule; Th2; subtype of helper T lymphocyte; JAK; Janus kinase; STAT; signal transducer and activator of transcription; IL-4; Interle

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Mode of dendritic cell activation: The decisive hand in Th2/Th17 cell differentiation. Implications in asthma severity?

Keywords: مبدل سیگنال و فعال کننده رونویسی; Asthma; Dendritic cells; T helper 2 cells; T helper 17 cells; Eosinophils; Neutrophils; Ag; antigen; AHR; airway hyper responsiveness; APC; antigen presenting cell; ATS; American Thoracic Society; BAL; bronchoalveolar lavage; Bcl-6; B-cell lymphoma; C; co

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Systems biology of IL-6, IL-12 family cytokines

Keywords: مبدل سیگنال و فعال کننده رونویسی; Systems biology; Mathematical modeling; IL-6-type cytokines; Quantitative analyses; Epo; erythropoietin; gp; glycoprotein; hESC; human embryonic stem cells; EGF; epidermal growth factor; ERK; extracellular signal regulated kinase; HGF; hepatocyte growth f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleBreast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia

Keywords: مبدل سیگنال و فعال کننده رونویسی; BRK; breast tumor kinase; CC; cholangiocarcinoma; SPRR2A; small proline-rich protein 2A; SH2 and SH3; Src- homology domain 2 and 3; ErbB2/neu; human epidermal growth factor receptor 2; STAT; signal transducer and activator of transcription; non-RTK; non-r

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling dysregulates Bim expression in autoimmune lymphoproliferative syndrome

Keywords: مبدل سیگنال و فعال کننده رونویسی; ALPS; Bim; Bcl-2 pathway; IL-10; BH3 mimetic; ABT-737; T cell homeostasis; double negative T cells; apoptosis; ALPS; Autoimmune lymphoproliferative syndrome; CDR; Complementarity determining region; DNTC; Double negative T cells; IL-10R; IL-10 receptor; J

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Quality control mechanisms in cellular and systemic DNA damage responses

Keywords: مبدل سیگنال و فعال کننده رونویسی; DNA damage; Ageing; Ubiquitin proteasome system; DNA repair; Progeroid syndromes; Genome stability; ARF; adenosine diphosphate ribosylation factor; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BER; base excis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis

Keywords: مبدل سیگنال و فعال کننده رونویسی; Mast cells; T cells; IL-22; IL-17; psoriasis; atopic dermatitis; APC; Allophycocyanin; CD; Crohn disease; FITC; Fluorescein isothiocyanate; ILC3; Type 3 innate lymphoid cell; IL-17R; IL-17 receptor; PE; Phycoerythrin; PMA; Phorbol 12-myristate 13-acetate;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-κB signaling pathway

Keywords: مبدل سیگنال و فعال کننده رونویسی; AP-1; activator protein 1; Bcl3; B-cell leukemia protein 3; BVD; bovine viral diarrhea; BVDV; bovine viral diarrhea virus; cp; cytopathic; DENV; dengue fever virus; EBV; Epstein-Barr virus; hpi; hours post-infection; IFN-β; interferon-beta; IL; interle

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion

Keywords: مبدل سیگنال و فعال کننده رونویسی; AIF; apoptosis inducible factor; AP-1; activator protein-1; AKT; protein kinase B; Apaf-1; apoptosis protease activating factor-1; BAD; Bcl-2-associated death promoter; BCL-2; B-cell lymphoma 2; BCLxL; B-cell lymphoma-extra large; BH3; Bcl-2 homology doma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Interferon-γ in foam cell formation and progression of atherosclerosis

Keywords: مبدل سیگنال و فعال کننده رونویسی; IFN-γ; interferon-γ; IFNGR; IFN-γ receptor; VSMC; vascular smooth muscle cell; IL; interleukin; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; STAT; signal transducer and activator of transcription; NF-κB; nuclear factor-κB; TLR; Toll-lik

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The immune signaling pathways of Manduca sexta

Keywords: مبدل سیگنال و فعال کننده رونویسی; Insect immunity; RNA-Seq; Transcriptome; Gene annotation; Expression profiling; Atg; autophagy-related protein; aPKC; atypical protein kinase C; CF; control fat body; CH; control hemocytes; IF; induced fat body; IH; induced hemocytes; Deaf; deformed epide

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viral replication and cellular arrest

Keywords: مبدل سیگنال و فعال کننده رونویسی; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; Daxx; death domain-associated protein; STAT; signal transducer and activator of transcription; PI; propidium iodide; FACS; fluorescence-activated cell sorter; MTS; 3-(4,5-dimethylthiazol-2-yl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Leukemia inhibitory factor (LIF)

Keywords: مبدل سیگنال و فعال کننده رونویسی; Leukemia inhibitory factor; JAK/STAT/SOCS; LIF receptor; Embryonic stem cells; Pregnancy; Nerve and muscle; LIF; leukemia inhibitory factor; CNTF; ciliary neurotrophic growth factor; CT1; cardiotrophin 1; CLC; carditrophin-like cytokine; JAK; Janus kinase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Interleukin-6 enhances acid-induced apoptosis via upregulating acid-sensing ion channel 1a expression and function in rat articular chondrocytes

Keywords: مبدل سیگنال و فعال کننده رونویسی; ASICs; acid-sensing ion channels; ASIC1a; acid-sensing ion channel 1a; AA; adjuvant arthritis; IL-6; interleukin-6; RA; rheumatoid arthritis; JAK; janus kinase; STAT; signal transducer and activator of transcription; MAPK; mitogen-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch

Keywords: مبدل سیگنال و فعال کننده رونویسی; Crk; CT10 regulator of kinase; CRKL; Crk-like protein; ERK; extracellular signal regulated kinase; FCS; foetal calf serum; Gab1; Grb2-associated binder 1; Grb2; growth factor receptor bound protein 2; IL-6; interleukin-6; JAK; Janus kinase; HEK; human emb

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function

Keywords: مبدل سیگنال و فعال کننده رونویسی; Immune Regulation; NS5A Inhibitor; NS3 Inhibitor; ISG; APC; allophycocyanin; ASV; asunaprevir; CXCL; chemokine C-X-C motif ligand; DAA; direct-acting antiviral; DCV; daclatasvir; EMA; ethidium monoazide; EOT; end of treatment; FBS; fetal bovine serum; FIT

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha

Keywords: مبدل سیگنال و فعال کننده رونویسی; CNTF(R); Ciliary neurotrophic factor (receptor); EGF; Epidermal growth factor; ERK; Extracellular signal-regulated kinase; FRα; Folate receptor alpha; GPI; glycophosphatidylinositol; IFN; Interferon; IL-6(R); Interleukin 6 (receptor); ISG; Interferon sti

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies

Keywords: مبدل سیگنال و فعال کننده رونویسی; Follicular helper T cells; humoral immunity; primary immunodeficiencies; cytokine signaling; Bcl-6; B-cell lymphoma 6; cTFH; Circulating follicular helper T; DN; Double-negative; DP; Double-positive; GC; Germinal center; GOF; Gain of function; IL-10R; IL-

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons

Keywords: مبدل سیگنال و فعال کننده رونویسی; BH domain; Bcl-2 homology domain; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; CHX; cycloheximide; CREB; cAMP-response element-binding protein; DIV; days-in-vitro; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FC

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 and TNF-α expression in monocytes: Implications for chronic obstructive pulmonary disease

Keywords: مبدل سیگنال و فعال کننده رونویسی; IL-10; CXCL8; TNF-α; histone deacetylase 2; chronic obstructive pulmonary disease; transcriptional inhibition; Brd4-docking site; nuclear factor κB; AcK310p65; Acetylated lysine 310 residue of NF-κBp65; ARF; Acute respiratory failure; CBP; CREB-binding

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

IL33 Is a Stomach Alarmin That Initiates a Skewed Th2 Response to Injury and Infection

Keywords: مبدل سیگنال و فعال کننده رونویسی; IL33; Helicobacter pylori; Inflammatory Response; Gastric Cancer; AB; Alcian blue; DC; dendritic cell; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; HBSS; Hank's balanced salt solution;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of tumor progression by oral piceatannol in mouse 4T1 mammary cancer is associated with decreased angiogenesis and macrophage infiltration

Keywords: مبدل سیگنال و فعال کننده رونویسی; ARG-2; arginase-2; CD31; platelet endothelial cell adhesion molecule-1; CDK; cyclin-dependent kinase; COX-2; cyclooxygenase-2; DMEM; Dulbecco′s modified Eagle′s medium; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HIF-1α; hypoxi

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

A novel stereo bioactive metabolite isolated from an endophytic fungus induces caspase dependent apoptosis and STAT-3 inhibition in human leukemia cells

Keywords: مبدل سیگنال و فعال کننده رونویسی; HMC; (R)-5-hydroxy-2-methylchroman-4-one; MTT; 3-(4,5-Dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide; PARP-1; Poly(ADP-Ribose) Polymerase-1; PI; propidium iodide; Rh-123; Rhodamine-123; Z-VAD-fmk; benzyloxycarbonyl-Val-Ala-Asp fluoro-methyl-ketone

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

PIM kinase (and Akt) biology and signaling in tumors

Keywords: مبدل سیگنال و فعال کننده رونویسی; PIM kinases; Akt; Oncogenes; Cancer; Therapeutic resistance; AML; acute myeloid leukemia; AMPK; AMP activated protein kinase; CXCR-4; C-X-C chemokine receptor type 4; EGFR; epidermal growth factor receptor; EBV; Epstein-Barr virus; FLT3; FMS-like ty

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه