Keywords: صاف; Cre-loxP; GnRH; Smoothened; Fertility; Neuroendocrine;
مقالات ISI صاف (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: صاف; Anti-tumor drug; Hedgehog pathway; Apoptosis; Caspase8; Smoothened;
Keywords: صاف; 2,5-DXP; 2,5-diketopiperazine; ACC; adenoid cystic carcinomas; BBR; berberine; BET; bromodomain and extraterminal; CA; chebulagic acid; CPT; camptothecin; EMT; epithelial-mesenchymal transition; GSK3; glycogen synthase kinase 3-; HCC; hepatocellular carci
Keywords: صاف; Intestine; Hedgehog; Stroma; Inflammation; CXCL12; α-SMA; α smooth muscle actin; CXCL; C-X-C motif chemokine ligand; CXCR; C-X-C motif chemokine receptor; DMEM; Dulbecco's modified Eagle medium; DSS; dextran sodium sulfate; FCS; fetal calf serum; Gli; g
Keywords: صاف; 5-FU; 5-Fluorouracil; ABCB5; ATP-binding cassette sub-family B member 5; ABCC2; ATP-binding cassette sub-family C member 2; ABCG2; ATP-binding cassette sub-family G member 2; ACs; Anthocyanins; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; AP
Keywords: صاف; Oxysterols; Cancer; Polymorphism; Risk; Genetics; Cholesterol; 25(OH)D; 25-hydroxyvitamin D; ABC; ATP-binding cassette; AEBS; antiestrogen-binding site; BC; breast cancer; BCR; biochemical recurrence; CETP; cholesteryl ester transfer protein; CH25H; chole
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer
Keywords: صاف; 27-OHC; 27-hydroxycholesterol; ADT; androgen deprivation therapy; AR; androgen receptor; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; C/EBP; CCAAT / Enhancer binding proteins; CHOP; C/EBP homologous protein; CIP2A; can
Keywords: صاف; ADIG; adipogenin; PPARγ; peroxisome proliferator activated receptor γ; Hh; hedgehog; siRNA; small interfering RNA; TNFα; Tumor Necrosis Factor α; Mw; molecular weight; pI; theoretical isoelectric point; CDS; coding sequence; qPCR; quantitative real ti
Keywords: صاف; Hedgehog signaling; Smoothened; Cysteine-rich domain; Oxysterols; Molecular dynamics;
Keywords: صاف; Quinazolinone; Isoindolinone; Hedgehog pathway; Structure hopping; Smoothened; Gli;
Keywords: صاف; ADAM; a disintegrin and metalloprotease; ADEX; aberrantly differentiated endocrine exocrine; ALDH1; aldehyde dehydrogenase 1; CAFs; cancer associated fibroblasts; CDKN2A; cyclin dependent kinase inhibitor 2A; CSC; cancer stem cell; CTC; circulating tumor
Keywords: صاف; Hedgehog; Primary cilia; Smoothened; Tubulin acetylation;
Keywords: صاف; FAP; fibroadipogenic progenitors; PAX7; paired box 7; MRF; myogenic regulatory factor; Hh; Hedgehog; MyoD1; myogenic differentiation 1; Smo; Smoothened; Gli1; Gli family zinc finger 1; Ptch1; Patched 1; rRNA; ribosomal ribonucleic acid; CAGGS; CMV early e
Keywords: صاف; Smoothened; Hedgehog; GPCR; canonical signaling; noncanonical signaling
Keywords: صاف; Bloom syndrome; dyskeratosis congenita; genetic testing; Gorlin syndrome; Muir-Torre syndrome; nonmelanoma skin cancer; oculocutaneous albinism; Rothmund-Thomson syndrome; Werner syndrome; 5-FU; 5-fluorouracil; ADA1; adenosine deaminase 1; ADA-SCID; a
Keywords: صاف; Dopaminergic neurons; Sonic hedgehog; Smoothened; Parkinson's disease; 6-OHDA;
Keywords: صاف; AcTub; acetylated α-tubulin; BBS; Bardet-Biedl syndrome; βARKct; beta-adrenergic receptor kinase carboxyl-terminus; cAMP; cyclic AMP; C-tail; C-terminal tail; Epac; exchange protein directly activated by cAMP; ERK; extracellular signal-regulated kinas
Keywords: صاف; ACTH; Adrenocorticotropic hormone; caSmo; Constitutively active form of Smo; CK1; Casein kinase 1; DHEA; Dehydroepiandrosterone; E2; Estradiol; GH; Growth hormone; GSK3β; Glycogen synthase kinase-3β; Hh; Hedgehog; Kif7; Kinesin family member 7; PKA; Pro
Keywords: صاف; Hedgehog signaling pathway; Smoothened; Antagonist; GPCR; Scaffold hopping; Cancer therapyAUC, area under curve; CE, collision energy; DCM, dichloromethane; DIPEA, N,N-diisopropylethylamine; DMF, N,N-dimethylformamide; DMSO, dimethyl sulfoxide; DP, declus
Keywords: صاف; Hedgehog pathway; Smoothened; Antagonist; GPCR; Scaffold hopping; Cancer therapy
Keywords: صاف; Hedgehog; Smoothened; Patched; Metabolites; Sterols; Oxysterols;
Keywords: صاف; Morphogen; Smoothened; Patched; Gli; SuFu; Gal4;
Keywords: صاف; LPC; liver progenitor cell; Hh; Hedgehog; SHH; Sonic Hedgehog; IHH; Indian Hedgehog; DHH; Desert Hedgehog; PTCH1; Patched 1; SMO; Smoothened; GLI; GLI-Kruppel family of transcription factors; GLI-A; GLI full-length activator; Pc; primary cilia; TAA; thioa
Keywords: صاف; Cell signaling; Combination chemotherapy; Novel antitumor agents; Hedgehog; Smoothened; Targeted therapy;
Keywords: صاف; aSMA; alpha smooth muscle actin; BMP-7; bone morphogenic protein-7; EMT; epithelial-to-mesenchymal transition; GFAP; glial fibrillary acidic protein; Gli; glioblastoma; Hh; hedgehog; HSC; hepatic stellate cell; MF; myofibroblast; Ptc; patched; Smo; smooth
Keywords: صاف; GLI1/2/3; glioma-associated oncogene homologue 1/2/3; PTCH; patched; SMO; smoothened; SUFU; suppressor of fused; CDO; CAM-related/downregulated by oncogenes; BOC; brother of CDO; GAS1; growth arrest-specific 1; PKA; protein kinase A; GSK3β; glycogen synt
Keywords: صاف; Development; Gastric Epithelium; Signal Transduction; Tissue Regeneration; CCK-BR; cholecystokinin/gastrin-B receptor; ECL; enterochromaffin-like; GFP; green fluorescent protein; GKO; gastrin deficient; Gli1; glioma-associated oncogene homolog 1; Ihh; Ind
Keywords: صاف; BrdU; bromodeoxyuridine; Cdk; cyclin-dependent kinase; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle medium; Myo7a; myosin VIIA; P2; postnatal day 2; Pax2; paired box 2; pRb; retinoblastoma protein; Ptc; patched; Rb1; retinoblas
Keywords: صاف; 7-KC; 7 ketocholesterol; ACAT; acyl-CoA cholesterol acyl transferase; CHEH; cholesterol-5-6-epoxide hydrolase; CNS; central nervous system; CT; cholestane 3β-5α-6β triol; EC; epoxycholesterol; EGF; epidermal growth factor; ER; endoplasmic reticulum; ER
Sinomenine reduces growth and metastasis of breast cancer cells and improves the survival of tumor-bearing mice through suppressing the SHh pathway
Keywords: صاف; Hh; Hedgehog; SMO; smoothened; Ptch1; Patched 1 receptor 1; SHh; sonic hedgehog; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; EMT; epithelial-mesenchymal transition; qPCR; quantitative polymerase chain reaction; IHC; hematoxylin
The Sonic Hedgehog signaling pathway regulates inferior alveolar nerve regeneration
Keywords: صاف; SC; Schwann cell; Shh; Sonic Hedgehog; Ptch1; patched 1; Smo; Smoothened; Gli; glioma-associated oncogene homolog; IAN; inferior alveolar nerve; GFP; green fluorescent protein; PGP9.5; protein gene product 9.5; FITC; fluoresceinisothiocyanate; MBP; myelin
G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts
Keywords: صاف; G-protein coupled receptor kinase; Smoothened; GATA; Atrio-ventricular septal defect; Heart development;
Expression Undercurrents of Sonic Hedgehog in Colorectal and Pancreatic Cancers
Keywords: صاف; Colorectal cancer; CRC; Pancreatic cancer; PC; Sonic hedgehog; SHH; Indian hedgehog; IHH; Desert hedgehog; DHH; Bone morphogenetic protein; BMP; Transforming growth factor; TGFβ; Pancreatic intra epithelial lesions; PanIN; Pancreatic ductal adenocarcinom
Keratinocyte Sonic Hedgehog Upregulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1Â Secretion
Keywords: صاف; BCC; basal cell carcinoma; CC; Collaborative Cross; EDN; endothelin; hgf; hepatocyte growth factor; P10; postnatal day 10; Shh; sonic hedgehog; Smo; smoothened;
Reduced Smoothened level rescues Aβ-induced memory deficits and neuronal inflammation in animal models of Alzheimer's disease
Keywords: صاف; Alzheimer disease; Inflammation; Learning and memory; Smoothened; AD; Alzheimer's disease; SHH; sonic hedgehog; ALS; amyotrophic lateral sclerosis; NPC; Niemann-Pick disease type C; AD flies; Aβ expressing flies; AMPs; antimicrobial peptides;
Hypomorphic Smo mutant with inefficient ciliary enrichment disrupts the highest level of vertebrate Hedgehog response
Keywords: صاف; Smoothened; Sonic hedgehog signaling; Primary cilia; Mouse development;
Sonic hedgehog regulates the pathfinding of descending serotonergic axons in hindbrain in collaboration with Wnt5a and secreted frizzled-related protein 1
Keywords: صاف; Shh; Sonic Hedgehog; Sfrp1; Secreted frizzled-related protein 1; PCP; planar cell polarity; 5-HT; 5-hydroxytryptamine; E10.5; Embryonic day 10.5; A-P; Anterior to posterior; Fzd3; Frizzled 3; DMSO; Dimethylsulfoxide; Ptch1; Patched 1; Smo; Smoothened; R4;
Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo
Keywords: صاف; Hedgehog inhibitor; In vivo pharmacokinetics; Gram-scale synthesis; ADME-Tox; LS180 xenograft; Acylguanidine; Hh; Hedgehog; Shh; Sonic Hedgehog; Ptch; Patched; Smo; Smoothened; BCC; basal cell carcinoma; PE; petroleum ether; SRB; sulforhodamine B; Shh-CM
Discovery and characterization of a potent Wnt and hedgehog signaling pathways dual inhibitor
Keywords: صاف; Wnt signaling pathway; Hedgehog signaling pathway; Porcupine; Smoothened; Antagonist; Stem cell; Cancer therapy; AUC; area under the plasma time-concentration curve; BCC; basal cell carcinoma; BPO; benzoyl peroxide; CL; clearance; CSC; cancer stem cells;
Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells
Keywords: صاف; Apoptosis; Cell death; Noxa; TAp73; EGR1; GANT61; Hedgehog signaling; Rhabdomyosarcoma; Medulloblastoma; ARMS; alveolar RMS; CNS; central nervous system; DSMZ; Deutsche Sammlung von Mikroorganismen und Zellkulturen; EGR1; early growth response protein 1;
Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium
Keywords: صاف; BBS8; Bardet-Biedl syndrome 8; bFGF; basic fibroblast growth factor; BMP; bone morphogenetic protein; BMSCs; bone marrow-derived hematopoietic stem cells; ECM; extracellular matrix; EGF; epidermal growth factor; EMT; epithelial-to-mesenchymal transition;
Salvianolic Acids for Injection (SAFI) promotes functional recovery and neurogenesis via sonic hedgehog pathway after stroke in mice
Keywords: صاف; Stroke; Salvianolic Acids for Injection; Neurogenesis; Neural progenitor cells; Sonic hedgehog signaling pathway; tPA; tissue plasminogen activator; NPCs; neural progenitor cells; SVZ; subventricular zone; Shh; sonic hedgehog; Smo; Smoothened; BDNF; brain
ReviewNew paradigms for the Hedgehog signaling network in mammary gland development and breast Cancer
Keywords: صاف; Shh; Sonic Hedgehog; Ihh; Indian Hedgehog; Dhh; Desert Hedgehog; Patched-1; Patched-1; Smo; Smoothened; PKA; Protein Kinase A; SUFU; Suppressor of Fused; Hhip; Hedgehog interacting protein; Gas1; growth arrest specific protein 1; TID; tumorous imaginal di
Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities
Keywords: صاف; Asp; aspartate; BisII; bisindolylmaleimideII; CYC; cyclopamine; MTT; thiazolyl blue tetrazolium bromide; PKCδ; PKC delta; PMA; phorbol 12-myristate 13-acetate; SHH; sonic hedgehog; Smo; Smoothened; STP; straurosporine; TfR,; transferrin receptor; UCPH; U
Short communicationHedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes
Keywords: صاف; Hh; Hedgehog; MAML3; mastermind-like3; RBPJ; recombination signal binding protein for immunoglobulin-kappa-J region; PD-1; programmed death-1; PDL-1; programmed death ligand-1; Smo; Smoothened; PSK; protein-bound polysaccharide; NKG2D; natural-killer grou
Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer
Keywords: صاف; Hypoxia; Hedgehog signaling; Smoothened; Mastermind-like 3; RBPJ; Pancreatic cancer;
Oxysterols: From cholesterol metabolites to key mediators
Keywords: صاف; ABC; ATP-binding cassette; ACAT; acyl-coenzyme A cholesterol acyltransferase; C4; 7-hydroxycholestenone; CA; cholestanoic acid; CH25H; cholesterol-25-hydroxylase; ChEH; cholesterol epoxide hydrolase; CNS; central nervous system; CSF; cerebrospinal fluid;
Hedgehog receptor function during craniofacial development
Keywords: صاف; Sonic hedgehog; Craniofacial development; Disease; Holoprosencephaly; Dispatched; Scube2; Patched1; Patched2; Gas1; Cdon; Boc; Lrp2/megalin; Gpr161; Smoothened; EvC1/2;
Targeting cancer stem cells in solid tumors by vitamin D
Keywords: صاف; CSC; Cancer stem cell; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; EpCAM; Epithelial cell adhesion molecule; PROM1; Prominin 1; CXCR4; C-X-C chemokine receptor type 4; SDF1; Stromal cell-derived factor 1; ALDH-1; Aldehyde dehydrogenease-1; EMT; Epithelial-
Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion
Keywords: صاف; RPS3; ribosomal protein S3; PTCH1; Patched1; SMO; Smoothened; SUFU; suppressor of fused; GLI; glioma-associated oncogene homolog; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; NHOst; normal human osteoblast cells; RNAi; RNA interferen