Keywords: EMT; epithelial mesenchymal transition; qRT-PCR; quantitative real time polymerase chain reaction; CXCL12; C-X-C motif chemokine ligand 12; CXCR4; C-X-C chemokine receptor type 4; CK7; cytokeratin-7; CDH1; E-cadherin; CLDN4; claudin-4; HIF-1A; hypoxia ind
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Keywords: AA; aortic aneurysm; TAA; thoracic aortic aneurysms; AAA; abdominal aortic aneurysm; TAAD; thoracic aortic aneurysms and dissections; FBN1; Fibrillin 1; MFAP5; Microfibril associated protein 5; SMC; smooth muscle cell; MFS; Marfan syndrome; MYH11; myosin
Keywords: Monozygotic twins; Down syndrome; Discordance; Exome sequencing; TGFBR2; ITPR1; RYR2;
Keywords: miRNAs; Embryonic stem cells; Pluripotency; Reprogramming; Self-renewal; 3â² UTR; 3â²-untranslated region; AGOs; Argonaute proteins; BMP; bone morphogenetic protein; CSDC2; cold-shock domain-containing protein C2; DGCR8; DiGeorge syndrome critical regio
Keywords: APC(s); antigen presentation cell(s); ARG1; arginase-1; Breg(s); regulatory B (cells); CAF(s); cancer-associated fibroblast(s); CD; cluster of differentiation protein; CD40L; cluster of differentiation protein 40 ligand; C/EBP; CAAT/enhancer binding prote
Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
LncRNA HOXA-AS2 and its molecular mechanisms in human cancer
Keywords: lncRNA; HOXA-AS2; Diagnosis; Therapeutic target; Prognosis; APL; Acute promyelocytic leukemia; ATRA; All trans retinoic acid; Bax; BCL2-Associated X; BC; Breast cancer; Bcl-2; B-cell lymphoma-2; c-Myc; MYC proto-oncogene; CRC; Colorectal cancer; DDIT3; DN
The genetic polymorphisms of TGFβ superfamily genes are associated with litter size in a Chinese indigenous sheep breed (Hu sheep)
Keywords: Hu sheep; FecB; TGFBR2; GDF9; Litter size; KASPar;
Protein network module-based identification of key pharmacological pathways of Curcuma phaeocaulis Val. acting on hepatitis
Keywords: CP; Curcuma phaeocaulis Val.; ALT; Alanine aminotransferase; AST; Aspartate transaminase; LDH; Lactate dehydrogenase; PIN; Protein interaction network; HBV; Hepatitis B virus; HCV; Hepatitis C virus; TCM; Traditional Chinese medicine; PPIs; Protein-protei
Identification of circular RNAs in human aortic valves
Keywords: AGO; argonaute; ANK3; ankyrin 3; BAV; bicuspid aortic valve; CASP3; Caspase-3; circRNA; circular RNA; COL6A6; collagen, type VI, alpha 6; ECM; extracellular matrix; ERBB4; V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; FBN; fibrillin 1;
Arthrogryposis as neonatal presentation of Loeys-Dietz syndrome due to a novel TGFBR2 mutation
Keywords: Arthrogryposis multiplex congenita; Loeys Dietz syndrome; Aortic root dilatation; Arterial tortuosity; Cleft palate; TGFBR2 gene; Connective tissue disorder; Aneurysm; LDS; Loeys Dietz syndrome; TGFBR1; transforming growth factor β receptor I; TGFBR2; tr
Functional characteristics of a novel SMAD4 mutation from thoracic aortic aneurysms (TAA)
Keywords: AA; aortic aneurysm; TAA; thoracic aortic aneurysms; TGF-β; transforming growth factor β; R-Smads; receptor-regulated Smads; FBN1; fibrillin-1; TGFBR1; TGF-β receptor 1; TGFBR2; TGF-β receptor 2; TGFB2; transforming growth factor beta 2; TGFB3; transf
An androgen-regulated miR-2909 modulates TGFβ signalling through AR/miR-2909 axis in prostate cancer
Keywords: TGFβ receptor II; TGFBR2; Prostate cancer; PCa; Androgen deprivation therapy; ADT; Hormone-sensitive PCa; HSPC; Apoptosis antagonizing transcription factor; AATF; Androgen receptor; AR; Dihydrotestosterone; DHT; PSA; Prostate Specific Antigen; Estrogen r
Osteogenesis imperfecta: new genes reveal novel mechanisms in bone dysplasia
Keywords: ADAMTS; A disintegrin and metalloprotease with thrombospondin motifs; AR-OI; autosomal recessive osteogenesis imperfecta; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; BiP; binding immunoglobulin protein; BMDD; bone mineraliz
Gross deletions in FBN1 results in variable phenotypes of Marfan syndrome
Keywords: Marfan syndrome; MLPA; FBN1; Gross deletion; Phenotype; cbEGF; Calcium-binding EGF-like domains; TB; TGFβ binding domains; CNVs; copy number variations; FBN1; fibrillin-1; MFS; Marfan syndrome; MLPA; multiplex ligation-dependent probe amplification; PGM;
Genetic Modifiers of Patent Ductus Arteriosus in Term Infants
Keywords: candidate gene; CREBB; TGFBR2; TRAF1; NBDPS; National Birth Defects Prevention Study; PDA; Patent ductus arteriosus; SNP; Single-nucleotide polymorphism; TDT; Transmission disequilibrium testing;
MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis
Keywords: Colorectal cancer; MiR-17~92; TGFBR2; HIF1α; VEGFACRC, colorectal cancer; 3′ UTR, 3′ untranslated region; TGFBR2, transforming growth factor β type II receptor; HIF1α, hypoxia induced factor-1α; VEGFA, vascular endothelial growth factor A; DSS, dextran su
Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1
Keywords: TGFBR2; Colorectal cancer; Microsatellite instability; Glycosylation; LFNG; Notch1;
Cartilage Oligomeric Matrix Protein Increases in Photodamaged Skin
Keywords: BSA; bovine serum albumin; COMP; cartilage oligomeric matrix protein; ECM; extracellular matrix; NHDF; normal human dermal fibroblast; PBS; phosphate-buffered saline; TGF; transforming growth factor; UV; ultraviolet; TGFBR2; TGF-β type II receptor;
The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis
Keywords: miRNA; Micro-RNA; BLM; Bleomycin; IPF; Idiopathic pulmonary fibrosis; TGFBR2; Transforming growth factor-β type II receptor; Fn; Fibronectin; SMA-α; Smooth muscle actin-α; Smad2/3; Mothers against DPP homolog 2/3; TGF-β; Transformation growth factor Î
Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2
Keywords: Colon Cancer; Signal Transduction; Tumor Suppressor; RNA Editing; A10; 10 adenines microsatellite; cDNA; complementary DNA; CRC; colorectal cancer; MSI-H; microsatellite instability-high; p-SMAD2; phosphorylated SMAD2 protein; PCR; polymerase chain reacti
The early manifestation, tumor-specific occurrence and prognostic significance of TGFBR2 aberrant splicing in oral carcinoma
Keywords: Oral cancer; TGFβ signaling; Alternative splicing; TGFBR2; Kinase domain; Sequencing;
Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells
Keywords: TGFβ; transforming growth factor β; BMP; bone morphogenetic protein; BMPR2; BMP type II receptor; ACVR2; activin type II receptor; ECD; extracellular domain; AMHR2; anti-Müllerian hormone type II receptor; TGFBR2; TGFβ type II receptor; FSH; follicle-
TGFBR2 gene polymorphism is associated with ossification of the posterior longitudinal ligament
Keywords: Autoimmune disease; Ossification of posterior longitudinal ligament; TGFB; TGFBR2
Transforming Growth Factor-β Signaling in Hepatocytes Promotes Hepatic Fibrosis and Carcinogenesis in Mice With Hepatocyte-Specific Deletion of TAK1
Keywords: Liver Cancer; Mouse Model; Signal Transduction; Oncogene; ALT; alanine aminotransferase; CTGF; connective tissue growth factor; DEN; n-nitrosodiethylamine; GFP; green fluorescent protein; HCC; hepatocellular carcinoma; IKK; IκB kinase; IL; interleukin; J
miR-21 modulates tumor outgrowth induced by human adipose tissue-derived mesenchymal stem cells in vivo
Keywords: MSC; mesenchymal stem cell; hADSCs; human adipose-derived stem cells; TGFBR2; transforming growth factor beta receptor II; STAT3; signal transducer and activator of transcription 3; VEGF; vascular endothelial growth factor; GAPDH; glyceraldehyde 3-phospha
Short CommunicationTarget genes of microsatellite sequences in head and neck squamous cell carcinoma: Mononucleotide repeats are not detected
Keywords: MSI; Microsatellite instability; HNSCC; head and neck squamous cell carcinoma; MMR; mismatch repair; LOH; loss of heterozygosity; bp; base pair; TGFBR2; TGF-beta type II receptor 2; Microsatellite sequences; Microsatellite instability; Target genes; Head
Concordant Promoter Methylation of Transforming Growth Factor-Beta Receptor Types I and II Occurs Early in Esophageal Squamous Cell Carcinoma
Keywords: TGFBR1; TGFBR2; Smad4; Methylation; Esophageal squamous cell carcinoma
Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation
Keywords: Tgfbr2; Conditional knockout; Hypertrophic chondrocyte; Indian hedgehog
MicroRNA-337 is associated with chondrogenesis through regulating TGFBR2 expression
Keywords: miR-337; TGFBR2; Chondrogenesis
Meta-analysis of the association between single nucleotide polymorphisms in TGF-β receptor genes and abdominal aortic aneurysm
Keywords: Abdominal aortic aneurysm; Single nucleotide polymorphism; TGFBR1; TGFBR2;
Recent molecular biological progress in Marfan syndrome and Marfan-associated disorders
Keywords: Marfan syndrome; Ageing; FBN1; TGFBR1; TGFBR2; Pathogenic mechanism
Genetic Testing in Aortic Aneurysm Disease: PRO
Keywords: Familial thoracic aortic aneurysm and dissection; Marfan syndrome; Loeys Dietz syndrome; FBN1; TGFBR1; TGFBR2; MYH11; ACTA2;
Bladder Stromal Loss of Transforming Growth Factor Receptor II Decreases Fibrosis After Bladder Obstruction
Keywords: urinary bladder; receptors; transforming growth factor beta; urinary bladder neck obstruction; collagen; fibrosis; ECM; extracellular matrix; FBS; fetal bovine serum; IHC; immunohistochemical staining; KO; knockout; pBOO; partial bladder outlet obstructio
Tgfbr2 is required for development of the skull vault
Keywords: Tgfbr2; Parietal bone; Frontal bone; Intramembranous bone formation; Calvaria; Osteoprogenitor; Proliferation; Osteoblast differentiation;
TGFBR2 gene expression and genetic association with schizophrenia
Keywords: TGFBR2; Gene expression; Leukocytes; Association analysis; Schizophrenia
Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms, and sporadic aneurysms
Keywords: AAA; abdominal aortic aneurysm; FTAA; familial thoracic aortic aneurysm; ICAM; intercellular adhesion molecule; MD; medial degeneration; MFS; Marfan syndrome; PCR; polymerase chain reaction; TAA; thoracic aortic aneurysm; TCR BV; T-cell receptor β-chain
IGFBP3 Promoter Methylation in Colorectal Cancer: Relationship with Microsatellite Instability, CpG Island Methylator Phenotype, p53
Keywords: Colon cancer; IGFBP3; methylation; CIMP; MSI; BAX; BCL2-associated X protein; CACNA1G; calcium channel; voltagedependent; T type alpha-1G subunit; CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, CIP1); CDKN2A; cyclin-dependent kinase inhibitor 2A (p16,
Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints
Keywords: Micromass culture; Tgfbr2; Chondrocyte; Synovial joint; Sternum; Skull;