An elevated pro-inflammatory cytokines profile in Behcet's disease: A multiplex analysis
Keywords: Innate immunity; Th1; Th2; Th17; Cytokine profiles; Behcet's disease;
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Atrophying pityriasis versicolor as an idiosyncratic TÂ cell-mediated response to Malassezia: A case series
Keywords: pityriasis versicolor; atrophy; Malassezia; CD4; CD8; TH1; TH2; GATA3; CXCR3; MMP; matrix metalloproteinase; PAS; periodic acid-Schiff; PV; pityriasis versicolor; TH; helper T;
Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese
Keywords: Type 1 diabetes (T1D); Anti-GAD; IgE; Tyrosine kinase 2 (TYK2); Th1/Th2; Virus; T1D; Type 1 diabetes; Th1; type 1 T helper; TYK2; Tyrosine kinase 2; HIES; hyper-IgE syndrome; Th2; type 2 T helper; Anti-GAD Ab; anti-glutamic acid decarboxylase antibody; YH
Exposure to particulate matter 2.5 (PM2.5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity
Keywords: Macrophage; PM2.5; Th1; Th17;
A novel nanoemulsion vaccine induces mucosal Interleukin-17 responses and confers protection upon Mycobacterium tuberculosis challenge in mice
Keywords: Mucosal vaccines; Nanoemulsion; IL-17 Responses; Ag85B; Antigen 85B; ANOVA; Analysis of variance; BCG; Mycobacterium bovis bacillus Calmette-Guerin; BCIP/NBT; 5-Bromo-4-chloro-3-indolyl phosphate/ nitro blue tetrazolium chloride; C; Centigrade; C57BL/6J;
Epigenetic alterations in chronic disease focusing on Behçet's disease: Review
Keywords: ncRNAs; non-coding RNAs; BD; Behçet's disease; MHC; major histocompatibility complex; HLA; Human Leukocyte Antigen; TNF; Tumor Necrosis Factor; IL-10; interleukin-10; MEFV; Mediterranean fever; TH1; T-helper 1; Me5C; 5-methyl cytosine; DNMTs; DNA methy
Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity
Keywords: AMP; antimicrobial peptide; EDC; epidermal differentiation complex; LCE; late cornified envelope; LCE3B/C-del; the 32 kb deleted fragment comprising LCE3B and 3C; NN; normal skin; PN; nonlesional psoriatic skin; PP; lesional psoriatic skin; Th1; T helper
CCR6+ Th cells in the cerebrospinal fluid of persons with multiple sclerosis are dominated by pathogenic non-classic Th1 cells and GM-CSF-only-secreting Th cells
Keywords: T cells; Cerebrospinal fluid; Multiple sclerosis; CCR6; Th1; Th17; GM-CSF;
Leishmania infantum-specific IFN-γ production in stimulated blood from dogs with clinical leishmaniosis at diagnosis and during treatment
Keywords: CBC; complete blood cell count; ConA; concanavalin A; DNA; deoxyribonucleic acid; ELISA; enzyme-linked immunosorbent assay; EU; ELISA units; IFAT; indirect immunofluorescence technique; IFN-γ; interferon-gamma; IL-10; interleukin-10; IL-4; interleukin 4;
Research paperRole of heterogeneous cell population on modulation of dendritic cell phenotype and activation of CD8 T cells for use in cell-based immunotherapies
Keywords: DC; dendritic cell; GM-CSF; granulocyte macrophage colony stimulating factor; TLR; toll-like receptor; MPLA; monophosphoryl lipid A; LPS; lipopolysaccharide; TH1; T-helper 1; TH2; T-helper 2; OVA; ovalbumin; CFSE; carboxyfluorescein succinimidyl ester; MF
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency
Keywords: Autoimmunity; CVID; IL-4Rα; Th1; T cell; Phospho-flow cytometry; IL-4 signaling; Hypogammaglobulinemia;
Vaccination with the polymorphic membrane protein A reduces Chlamydia muridarum induced genital tract pathology
Keywords: DDA/MPL; dimethyldioctadecylammonium bromide/monophosphoril lipid A; MOMP; major outer membrane protein; Mon-CpG; Montanide ISA 720/CpG-ODN 1826; ODN; oligodeoxynucleotide; Pmp; polymorphic membrane protein; TH1; T-helper 1; Chlamydia muridarum; Genital t
A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice
Keywords: BAL; bronchoalveolar lavage; BCG; Bacillus Calmette et Guerin; CFUs; colony-forming units; cGMP; current Good Manufacturing Practices; hRSV; human respiratory syncytial virus; FI-hRSV; formalin-inactivated hRSV; HI-hRSV; heat-inactivated hRSV; FACS; fluor
Blood to skin recirculation of CD4+ memory T cells associates with cutaneous and systemic manifestations of psoriatic disease
Keywords: PBMC; peripheral blood mononuclear cells; TCM; central memory T cells; TEM; effector memory T cells; TEFF; effector T cells; PASI; Psoriasis Area and Severity Index; CRP; C-reactive protein; CLA; cutaneous lymphocyte-associated antigen; Th1; T helper 1 ce
Quercitrin extracted from Tartary buckwheat alleviates imiquimod-induced psoriasis-like dermatitis in mice by inhibiting the Th17 cell response
Keywords: Quercitrin; Psoriasis; Keratinocyte; Th17 cell; Cyclosporine A; YDHH; quercitrin; IMQ; imiquimod; LPS; lipopolysaccharide; CsA; cyclosporine A; IL; interleukin; TNF; tumor necrosis factor; IFN; interferon gamma; Th1; T-helper 1 cell; Th17; T-helper 17 cel
Medicinal benefits of Nigella sativa in bronchial asthma: A literature review
Keywords: Nigella sativa; Black seed; Asthma; Traditional medicine; Clinical studies; NS; Nigella sativa L.; GINA; Global Initiative for Asthma; IL; Interleukin; ACT; Asthma Control Test; FEV1; forced expiratory volume in one second; Th1; Type 1 T helper (Th1) cell
Amelioration of adjuvant-induced arthritis in CCDC134-overexpressing transgenic mice
Keywords: CCDC134; Th1; Th17; Adjuvant-induced arthritis;
Controlling the pro-inflammatory function of 6-sulfo LacNAc (slan) dendritic cells with dimethylfumarate
Keywords: DMF; dimethylfumarate; FAE; fumaric acid ester; GSH; glutathione; slanDC; 6-sulfo LacNAc-expressing dendritic cells; Th17; T helper cells producing interleukin 17; Th1; T helper cells producing interferon gamma; TNF-α; tumor necrosis factor alpha; MS;
IL-21 May Promote Granzyme B-Dependent NK/Plasmacytoid Dendritic Cell Functional Interaction in Cutaneous Lupus Erythematosus
Keywords: GrB; granzyme B; LE; lupus erythematosus; NK; natural killer; pDC; plasmacytoid DC; Th1; T helper 1; Th17; T helper 17;
The phosphodiesterase 4 inhibitor apremilast inhibits Th1 but promotes Th17 responses induced by 6-sulfo LacNAc (slan) dendritic cells
Keywords: cAMP; cyclic adenosine monophosphate; slanDC; 6-Sulfo LacNAc-expressing dendritic; cells PDE; phosphodiesterase; Th17; T helper cells producing interleukin 17; Th1; T helper cells producing interferon gamma; TNF-α; Tumor necrosis factor alpha; iNOS; indu
Increased of the hepatocytes and splenocytes apoptosis accompanies clinical improvement and higher survival in mice infected with Trypanosoma cruzi and treated with highly diluted Lycopodium clavatum
Keywords: Apoptosis; Cytokine; Homeopathy; Lycopodium clavatum; Trypanosoma cruzi; Th1; T helper cell type 1; Th2; T helper cell type 2; TNF-α; tumor necrosis factor alpha; IFN-γ; Intereferon gamma; IL-6; Interleukin 6; IL-4; Interleukin 4;
TIPS pentacene loaded PEO-PDLLA core-shell nanoparticles have similar cellular uptake dynamics in M1 and M2 macrophages and in corresponding in vivo microenvironments
Keywords: Asthma; LPS; Nanoparticle; Pulmonary drug delivery; Inflammation; PEG; polyethylene glycol; Th1; T helper cell type 1; Th2; T helper cell type 2; AAMs; alternatively activated macrophage; PLGA; poly(lactide-co-glycolide); LiLa; lipid-latex hybrid; PtdSer;
Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease
Keywords: Rainbow trout; Proliferative kidney disease; PKD; Tetracapsuloides bryosalmonae; Temperature; Immune response; Resistance; Tolerance; Th1; Th2;
Nrf2 signaling pathway: Pivotal roles in inflammation
Keywords: ARE; antioxidant response element; CBP; cAMP-response-element-binding protein binding protein; COX-2; cyclooxygenase 2; Gclc; glutamate cysteine ligase catalytic subunit; Gclm; glutamate cysteine ligase regulatory subunit; GSH; glutathione; HO-1; heme oxy
Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment
Keywords: DFSP; dermatofibrosarcoma protuberans; FS-DFSP; fibrosarcoma in dermatofibrosarcoma protuberans; GSEA; gene set enrichment analysis; IHC; immunohistochemistry; IM; imatinib; Pt; patient; Th1; T helper type 1; TIL; tumor-infiltrating lymphocyte;
Cell Surface Expression of HLA-Cw6 by Human Epidermal Keratinocytes: Positive Regulation by Cytokines, Lack of Correlation to a Variant Upstream of HLA-C
Keywords: miR; microRNA; PS; psoriasis; SNP; single nucleotide polymorphism; Th1; T helper type 1;
Short communicationPredominance of Th1 response, increase of megakaryocytes and Kupffer cells are related to survival in Trypanosoma cruzi infected mice treated with Lycopodium clavatum
Keywords: Trypanosoma cruzi; Lycopodium clavatum; Megakaryocytes; Kupffer cells; Th1 response; Th1; T helper cell type 1; Th2; T helper cell type 2; TNF-α; tumor necrosis factor alpha; IFN-γ; Interferon gama; IL-10; Interleukin 10; IL-4; Interleukin 4; IL-17; Int
RhIL-11 treatment normalized Th1/Th2 and T-bet/GATA-3 imbalance in in human immune thrombocytopenic purpura (ITP)
Keywords: Immune thrombocytopenic purpura; IL-11; T-bet; GATA-3; Th1; Th2;
Effect of interleukin-10 gene promoter polymorphisms -1082 G/A and -592 C/A on response to therapy in children and adolescents with chronic hepatitis C virus infection
Keywords: HCV; hepatitis C virus; Th1; Type 1 helper T cells; Th2; Type 2 helper T cells; IL; interleukin; SNPs; single nucleotide polymorphisms; PEG-IFN; pegylated interferon; AST; aspartate amino transferase; ALT; alanine amino transferase; GGT; gamma-glutamyl tr
Delivery methods to increase cellular uptake and immunogenicity of DNA vaccines
Keywords: HIV; human immunodeficiency virus; AIDS; acquired immunodeficiency syndrome; HCV; hepatitis C virus; LAV; live attenuated viral vaccines; VLP; virus-like particles; IM; intramuscular; ID; intradermal; DC; dendritic cells; APC; antigen presenting cells; Th
EPSAH, an exopolysaccharide from Aphanothece halophytica GR02, improves both cellular and humoral immunity as a novel polysaccharide adjuvant
Keywords: Exopolysaccharide from Aphanothece halophytica GR02 (EPSAH); Adjuvant; Antibody; Th1
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response
Keywords: MS; multiple sclerosis; MB; methylene blue; EAE; experimental autoimmune encephalomyelitis; CNS; central nervous system; IFN; interferon; NF-κB; nuclear factor kappa B; AMPK; AMP-activated protein kinase; SIRT1; silent mating-type information regulation
Peripheral Blood Regulatory T-Cell and Type 1 Helper T-Cell Population Decrease after Hepatic Artery Embolization
Keywords: CD; cluster of differentiation; CTL; cytotoxic T lymphocytes; FOXP3; forkhead box P3; HAE; hepatic artery embolization; IFN-γ; interferon-γ; IL; interleukin-4; PBMC; peripheral blood mononuclear cell; Th1; type 1 helper T cells; Th2; type 2 helper T cel
MicroRNAs: New regulators of IL-22
Keywords: IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of
Increased βTrCP are associated with imiquimod-induced psoriasis-like skin inflammation in mice via NF-κB signaling pathway
Keywords: βTrCP; β-transducin repeat-containing protein; TNF; tumor necrosis factor; IMQ; animal model of imiquimod; IPI; induced psoriasis-like inflammation; ICAM-1; intercellular adhesion molecule 1; IL; interleukin; NF; nuclear factor; Th1; type 1 T; Psoriasis
Protective mechanisms of berberine against experimental autoimmune myocarditis in a rat model
Keywords: Berberine; Experimental autoimmune myocarditis; JAK-STAT; Th17; Th1
NanoUPLC-MSE proteomic analysis of osteoclastogenesis downregulation by IL-4
Keywords: IL-4; interleukin-4; IL; interleukin; OPG; osteoprotegerin; RANKL; receptor activator of nuclear factor kappa-B ligand; rRANKL; receptor activator of nuclear factor kappa-B ligand recombinant; JNK; c-Jun N-terminal kinase; TNF-α; tumor necrosis factor al
Influence of Th2 Cytokines on the Cornified Envelope, Tight Junction Proteins, and β-Defensins in Filaggrin-Deficient Skin Equivalents
Keywords: AD; atopic dermatitis; AMP; antimicrobial peptide; FLG; filaggrin; FLG-; filaggrin knockdown skin equivalent; hBD-1; human β-defensin 1; hBD-2; human β-defensin 2; hBD-3; human β-defensin 3; Th1; T helper type 1; Th2; T helper type 2; TJ; tight junct
Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli
Keywords: Proteomics; Chronic myeloid leukemia; Tyrosine kinase inhibitor; Th1; Angiogenesis;
Effect of dendritic cell state and antigen-presentation conditions on resulting T-cell phenotypes and Th cytokine profiles
Keywords: APC, antigen presenting cell; CBA, cytometric bead array; CCM, complete culture medium; DC, dendritic cell; MAGE-3, melanoma-associated antigen 3; Teff, T effector cell; Treg, regulatory T-cellMAGE-3; Th1; Th2; Th17; Antigen presentation; Dendritic cells
Epidermolysis Bullosa Acquisita: From Pathophysiology to Novel Therapeutic Options
Keywords: Breg; immunoregulatory B cell; EBA; epidermolysis bullosa acquisita; Flii; Flightless I; Hsp90; heat shock protein 90; IVIG; intravenous immunoglobulins; MHC; major histocompatibility complex; MMP; matrix metalloproteinase; NC; noncollagenous; Th1; T help
Recovery of antigen-specific T cell responses from dogs infected with Leishmania (L.) infantum by use of vaccine associated TLR-agonist adjuvant
Keywords: VL; visceral leishmaniasis; IFNγ; interferon gamma; Th1; T helper 1; TLR; toll like receptor; IFAT; immunofluorescence anti-Leishmania antibody testing; IDRI; Infectious Disease Research Institute; Con A; concanavalin A; TNFα; tumor necrosis factor alph
Enhancement of fibroblast activation protein α-based vaccines and adenovirus boost immunity by cyclophosphamide through inhibiting IL-10 expression in 4T1 tumor bearing mice
Keywords: Fibroblast activation protein α; Interleukin-10; Cyclophosphamide; Prime-boost strategy; Immunosuppression; Cancer vaccine; Ad; adenovirus; CAFs; cancer-associated fibroblasts; CpVR-FAP; a recombinant plasmid encoding human FAPα; CY; cyclophosphamide; E
The probiotic activity of Lactobacillus murinus against food allergy
Keywords: Diosgenin; Food allergy; Lactobacillus murinus; Probiotics; Th1;
Mechanisms of allergy and clinical immunologyEpicutaneous immunization with ovalbumin and CpG induces TH1/TH17 cytokines, which regulate IgE and IgG2a production
Keywords: Epicutaneous immunization; atopic dermatitis; eosinophil peroxidase; IgE; IgG2a; Toll-like receptor 9; TH1; TH17; AD; Atopic dermatitis; ALNC; Axillary and inguinal lymph node cell; APC; Allophycocyanin; EPIT; Epicutaneous allergen-specific immunotherapy;
ReviewEthnomedicinal uses, phytochemistry and pharmacological properties of the genus Boerhavia
Keywords: IL-2; Interleukin-2; NK; Natural Killer; TNF; Tumour Necrosis Factor; PBMCs; Peripheral Blood Mononuclear Cells; ROS; Reactive Oxygen Species; MAP; Mitogen-Activated Protein; ESR; Electron Spin Resonance; HBV; Hepatitis-B Virus; Th1; T helper 1; IFN; Inte
RSV-specific anti-viral immunity is disrupted by chronic ethanol consumption
Keywords: RSV; Respiratory syncytial virus; AUD; Alcohol-use disorder; Th1; Type 1 CD4+IFNγ+ T-helper cell; Th2; Type 2 CD4+IL-4+ T-helper cell; APC; Antigen-presenting cell;
Improvement of Sclerodermatous Graft-Versus-Host Disease in Mice by Niclosamide
Keywords: Ab; antibody; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; ALT; Alanine aminotransferase; AU; arbitrary unit; cGVHD; chronic GVHD; eGFP; enhanced green fluorescent protein; ERK; extracellular signal-regulated kinase; GVHD; graft-ve
Comparative immunity of Salmo salar and Oncorhynchus kisutch during infestation with the sea louse Caligus rogercresseyi: An enrichment transcriptome analysis
Keywords: Immune response; Atlantic salmon; Coho salmon; Caligus rogercresseyi; TH1; TH2; tlr22a2;
Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction
Keywords: AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan