Keywords: جریان بداخل; TINs; tumor-infiltrating neutrophils; TILs; tumor-infiltrating lymphocytes; NLR; neutrophil/lymphocyte rate; BC; bladder cancer; IHC; immunohistochemistry; OS; overall survival; NMIBC; non-muscle invasive bladder cancer; MIBC; muscle invasive bladder canc
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Keywords: جریان بداخل; APC; antigen presenting cell; APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like; BRCA1/2; breast cancer 1/2; BCSS; breast cancer specific survival; B2M; β-2-microglobulin; CAF; cancer associated fibroblast; CCL; chemokine ligand; CD
Keywords: جریان بداخل; ATM; ataxia telangiectasia mutated; ATR; ATM-Rad3-related; AMPK; AMP-activated protein kinase; AD; Alzheimer's disease; ARE; antioxidant response element; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BRAC1; Breast cancer 1
Keywords: جریان بداخل; IDC; invasive ductal carcinoma; IL-35; interleukin-35; Tregs; regulatory T cells; TILs; tumor-infiltrating lymphocytes; EBI3; Epstein-Barr Virus (EBV)-induced gene 3; Bregs; regulatory B cells; PFS; progression-free survival; OS; overall survival; ER; est
Keywords: جریان بداخل; CIK; cytokine-induced killer cells; PA-MSHA; Pseudomonas aeruginosa-mannose sensitive hemagglutinin; TILs; tumor-infiltrating lymphocytes; NK; natural killer cell; PD-L1; programmed death receptor ligand 1; DCs; dendritic cells; PRs; partial remissions; S
Keywords: جریان بداخل; APC; antigen presenting cells; CRD; carbohydrate recognition domain; DCs; dendritic cells; GDF-15; growth differentiation factor-15; IL; interleukin; IDO; indoleamine 2,3-dioxygenase; IFN-γ; interferon-γ; LXR; liver X receptors; M-CSF; macrophage-colony
Keywords: جریان بداخل; TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: جریان بداخل; BRAF; diagnosis; immune blockade; immunochemistry; melanoma; pathology; PD-1; PD-L1; targeted therapy; therapy; TILs; treatment
Keywords: جریان بداخل; Tumor microenvironment; TILs; Prognosis; Immune context; Immunoscore; NSCLC;
Keywords: جریان بداخل; Microsatellite instability; Nivolumab; PD-L1; Pembrolizumab; TILs;
Keywords: جریان بداخل; Chemotherapy; TNBCtype; Neoadjuvant; PIK3CA; Androgen receptor; TNBC; triple negative breast cancer; pCR; pathological complete response; HR; homologous recombination; EMT; epithelial-mesenchymal-transition; AR; androgen receptor; TILs; tumor-infiltrati
Keywords: جریان بداخل; FO; 5-FU+oxaliplatin; FI; 5-FU+irinotecan; FOC/FIC; FO/FI+Cetuximab; TILs; tumor infiltrating lymphocytes; TAMs; tumor associated macrophages; TAFs/CAFs; tumor/cancer associated fibroblasts; CRC; colorectal cancer; Spheroid model; Drug screening; Cancer c
Keywords: جریان بداخل; Breast cancer; Immune system; Biomarkers; Immunotherapies; Immune checkpoint blockade; Tumor vaccines; ADCC; antibody dependent cellular cytotoxicity; BiTES; bispecific single chain monoclonal antibodies; CAR; T cells engineered to express artificial chim
Keywords: جریان بداخل; Melanoma; targeted; therapy; molecular; BRAF; TILs
Generating the Abscopal Effect by Combining Proapoptotic Peptides With IL-12-Based Immunotherapy
Keywords: جریان بداخل; CTLA4; Cytotoxic T lymphocyte-associated antigen 4; DCs; Dendritic cells; IL-12; Interleukine-12; MDSCs; Myeloid-derived suppressor cells; NK cells; Natural killer cells; PAPs; Proapoptotic peptides; PD1; Programmed cell death protein 1; Tregs; Regulatory
Rescue of iCIKs transfer from PD-1/PD-L1 immune inhibition in patients with resectable tongue squamous cell carcinoma (TSCC)
Keywords: جریان بداخل; OSCC; Oral squamous cell carcinoma; TSCC; Tongue squamous cell carcinoma; HNSCC; Head and neck squamous cell carcinoma; iCIKs; Improving cytokine-induced killer cells; TILs; Tumour-infiltrating lymphocytes; PBMCs; Peripheral blood mononuclear cells; IRB;
Chemosensitivity, tumor infiltrating lymphocytes (TILs), and survival of postpartum PABC patients treated by neoadjuvant chemotherapy
Keywords: جریان بداخل; Pregnancy associated breast cancer; PABC; Post-partum breast cancer; Chemosensitivity; Prognosis; Tumor infiltrating lymphocytes; TILs;
Expression of B7-H2 on CD8+ T cells in colorectal cancer microenvironment and its clinical significance
Keywords: جریان بداخل; MHC; major histocompatibility complex; TCR; T cell receptor; CTLA-4; cytotoxic T lymphocyte associated antigen-4; PD-1; programmed deth-1; PD-L1; programmed deth-1 ligand; TILs; tumor infiltrating lymphocytes; SPF; specific pathogen free; B7-H2; T cells;
Notch signaling pathway dampens tumor-infiltrating CD8+ T cells activity in patients with colorectal carcinoma
Keywords: جریان بداخل; CCK-8; cell counting kit-8; CTLA-4; cytotoxic T-lymphocyte associated protein-4; DAPT; N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenyl glycinet-butyl ester; FBS; fetal bovine serum; GM-CSF; granulocyte-macrophage colony stimulating factor; IFN-γ; interf
Blocking Tim-3 or/and PD-1 reverses dysfunction of tumor-infiltrating lymphocytes in HBV-related hepatocellular carcinoma
Keywords: جریان بداخل; TIM3; Protéine PD-1; TILs; HBV; Carcinome hépatocellulaire; TIM3 (T cell Ig- and mucin-domain-containing molecule-3); PD-1 (Programmed cell death 1); TILs; HBV: hepatocellular carcinoma;
PD-1 pathway and its clinical application: A 20Â year journey after discovery of the complete human PD-1 gene
Keywords: جریان بداخل; hPD-1; Human Programmed Cell Death 1; PD-L; program death ligand; TILs; tumor-infiltrating lymphocytes; mAb; monoclonal antibody; NSCLC; non-small-cell lung cancer; RCC; renal-cell carcinoma; UBC; urothelial bladder cancer; TTF; time-to-treatment failure;
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: جریان بداخل; Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer
Keywords: جریان بداخل; TILs; Tumor-infiltrating lymphocytes; NSCLC; Prognosis; Lung cancer; Immunoscore;
HDAC inhibitors as epigenetic regulators for cancer immunotherapy
Keywords: جریان بداخل; AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist
FOXOs in cancer immunity: Knowns and unknowns
Keywords: جریان بداخل; 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot
Research paperMHC class II expression in lung cancer
Keywords: جریان بداخل; MHC Class II; Lung cancer; Immune biomarker; IHC; TILs;
Mini reviewRegulatory T cells as suppressors of anti-tumor immunity: Role of metabolism
Keywords: جریان بداخل; Treg cells; regulatory T cells; TILs; tumor infiltrating lymphocytes; FoxP3; forkhead-box-P3; CTLs; cytotoxic T lymphocytes; FAO; fatty acid oxydation; OXPHOS; oxydative phosphorilation; Treg; Metabolism; Tumor; Concomitant immunity; Glycolysis;
Development of novel avenues to overcome challenges facing CAR T cells
Keywords: جریان بداخل; AICD; activation-induced cell death; AMP; adenosine monophosphate; APC; antigen-presenting cells; ATP; adenosine triphosphate; CAFs; cancer-associated fibroblasts; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA4; cytotoxic T-lymphocyt
Heterogeneity of Tumor and Immune Cell PD-L1 Expression and Lymphocyte Counts in Surgical NSCLC Samples
Keywords: جریان بداخل; CD8; Immunotherapy; Non-small-cell lung cancer; PD-L1; TILs;
Development of CAR T cells designed to improve antitumor efficacy and safety
Keywords: جریان بداخل; 28z; CD28 + CD3ζ; 4-1BBL; 4-1BB ligand; B-ALL; B cell acute lymphatic leukemia; BBz; 4-1BB + CD3ζ; CAR; chimeric antigen receptor; CD40L; CD40 ligand; CRS; cytokine release syndrome; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DCs; dendriti
Transient exposure to proteins SOX2, Oct-4, and NANOG immortalizes exhausted tumor-infiltrating CTLs
Keywords: جریان بداخل; ACT; TILs; TICTLs; STICTLs; SON; Nuclear delivery; 3SI; 3-signal activation by antigen, costimulation, and third signal cytokine; ACT; Adoptive Cell Transfer Therapy; CTL; Cytotoxic T Lymphocyte; DN; Double negative T cells; DP; Double positive T cells; i
A morphological and immunophenotypic map of the immune response in Merkel cell carcinoma
Keywords: جریان بداخل; Merkel cell carcinoma; Cutaneous neuroendocrine carcinoma; Tumor-infiltrating lymphocytes; TILS; Tumor-specific CD8Â + T cells; PD-1/PD-L1 pathway; Antitumoral immunity;
ReviewCould B7-H4 serve as a target to activate anti-cancer immunity?
Keywords: جریان بداخل; TCR; T-cell receptor; MHC; major histocompatibility complex; APCs; antigen presenting cells; CTLA-4; cytotoxic T lymphocyte antigen-4; SNP; single nucleotide polymorphism; Tregs; regulatory T-cells; TILs; tumor infiltrating T cells; CAM; cancer-associated
Immune biomarkers PD-1/PD-L1 and TLR3 in malignant pleural mesotheliomas
Keywords: جریان بداخل; Pleura; Mesothelioma; Immunohistochemistry; PD-L1; PD-1; TLR3; TILs;
Interleukin (IL)-24 transforms the tumor microenvironment and induces anticancer immunity in a murine model of colon cancer
Keywords: جریان بداخل; IL-24; interleukin-24; PBMCs; peripheral blood mononuclear cells; MDA; melanoma differentiation-associated gene; IFN-γ; interferon-α; CTLA4; cytotoxic T-lymphocyte-associated protein 4; PD1; programmed cell death 1; TILs; tumor infiltrating lymphocytes;
FOXP3+ T regulatory lymphocytes in primary melanoma are associated with BRAF mutation but not with response to BRAF inhibitor
Keywords: جریان بداخل; BRAF inhibitor; FOXP3; melanoma; TILS; tumour infiltrating lymphocytes;
Tumor-infiltrating lymphocytes, forkhead box P3, programmed death ligand-1, and cytotoxic T lymphocyte-associated antigen-4 expressions before and after neoadjuvant chemoradiation in rectal cancer
Keywords: جریان بداخل; CD8; cluster of differentiation 8; NK; natural killer cell; MDSCs; myeloid-derived suppressor cells; TILs; tumor-infiltrating lymphocytes; FOXP3; transcription factor forkhead box P3; PD-L1; programmed death ligand-1; CTLA-4; cytotoxic T lymphocyte-associ
Defining the role of CD2 in disease progression and overall survival among patients with completely resected stage-II to -III cutaneous melanoma
Keywords: جریان بداخل; biomarker; melanoma; primary melanoma; prognosis; recurrence; survival; tumor-infiltrating lymphocytes; AJCC; American Joint Committee on Cancer; HPF; high-powered fields; IHC; immunohistochemistry; MSMC; Mount Sinai Medical Center; NK; natural killer; TI
Interfering with coinhibitory molecules: BTLA/HVEM as new targets to enhance anti-tumor immunity
Keywords: جریان بداخل; PD1; BTLA; HVEM; Anti-tumor immunity; Co-inhibitory molecules; Cosignaling; BTLA; B- and T-lymphocyte attenuator; CTLA-4; CTL-associated-antigen-4; CRD; cystein-rich domain; HVEM; herpes virus entry mediator; Ig; immunoglobulin; LIGHT; homologous to lymph
Functional Investigation of Fas Ligand Expressions in Human Non-Small Cell Lung Cancer Cells and Its Clinical Implications
Keywords: جریان بداخل; CM; complete medium; Ctrl; control; Ctrli; control siRNA; DMSO; dimethyl sulfoxide; FACS; flow cytometry; FasL; Fas ligand; FasLi; FasL siRNA; FBS; fetal bovine serum; H; hour; kDa; kilodalton; M; molar; MFI; mean fluorescent intensity; min; minute; mM; m
Research ArticleTumor progression-related transmembrane protein aspartate-β-hydroxylase is a target for immunotherapy of hepatocellular carcinoma
Keywords: جریان بداخل; HCC; hepatocellular carcinoma; ASPH; aspartate-β-hydroxylase; DCs; dendritic cells; TILs; tumor infiltrating lymphocytes; PBMCs; peripheral blood mononuclear cells; HBV; hepatitis B; HCV; hepatitis C; CTLs; cytotoxic T lymphocytes; TAAs; tumor-associated
Discovery and characterization of tRNAIle lysidine synthetase (TilS)
Keywords: جریان بداخل; tRNA; Lysidine; TilS; AUA codon; Wobble modification; Anticodon
Listeria-based HPV-16 E7 vaccines limit autochthonous tumor growth in a transgenic mouse model for HPV-16 transformed tumors
Keywords: جریان بداخل; PBMCs; peripheral blood mononuclear cells; HPV; human papillomavirus; TILs; tumor infiltrating lymphocytes; Lm; Listeria monocytogenes; LLO; listeriolysin O; CTL; cytotoxic T lymphocytes; RBC; red blood cells; ActA; actin assembly; ODU; optical density un
CD4+ T helper responses in squamous cell carcinoma of the head and neck
Keywords: جریان بداخل; SCCHN; squamous cell carcinoma of the head and neck; MLTC; mixed lymphocyte-tumor cell cultures; wt; wild type; PBMCs; peripheral blood mononuclear cells; CTLs; cytotoxic T lymphocytes; PBLs; peripheral blood lymphocytes; TILs; tumor-infiltrating lymphocy
New computational methods reveal tRNA identity element divergence between Proteobacteria and Cyanobacteria
Keywords: جریان بداخل; tRNA identity; Function logos; tRNA identity determinants; Lysylated isoleucine tRNA; TilS; Aminoacyl-tRNA synthetase; Proteobacteria; Cyanobacteria; Kullback–Leibler DivergencekIle model, lysylated isoleucine tRNA TFAM model; ID, Information Difference;
Tumor infiltrating lymphocytes (TILs): Lessons learned in 30 years of study
Keywords: جریان بداخل; TILs; Cancer; Cytokines; Fas; Adhesion molecules; APC; antigen presenting cell; CTL; cytotoxic T lymphocyte; CTLA-4; cytotoxic T lymphocyte antigen-4; FasL; Fas ligand; ICAM; intercellular adhesion molecule; IEL; intraepithelial lymphocyte; IFN; interfero