Keywords: توپویزومراز; MRSA; NBTI; Gyrase; Topoisomerase; TopoIV; Antibacterial;
مقالات ISI توپویزومراز (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: توپویزومراز; Naphthalene diimides; Drug design; DNA; G-quadruplex; Telomeric DNA; Topoisomerase; Antiproliferative; BASASA; Boltzmann Accessible Solvent Accessible Surface Area; BCL-2; B-cell lymphoma 2; dsDNA; double-stranded DNA; hTel; human telomeric; HSP90; heat s
Keywords: توپویزومراز; Doxorubicin; Cardiomyopathy; Topoisomerase; Heart failure; Cancer; Mitochondria; Oxidant stress; DNA damage
Keywords: توپویزومراز; Hybrid molecules; Anti-fungal; Anti-tubercular; Anti-malarial; anti-inflammatory; ACTs; artemesinin based combination therapy; CQ; chloroquine; CC50; concentration required to reduce growth by 50%; EC50; half maximal effective concentration; Fqa; ferroqui
Keywords: توپویزومراز; Topoisomerase; Integrase; Chemotherapy; Natural products; Pharmacology
Keywords: توپویزومراز; Batracylin; BAT; Tuftsin; Retro-tuftsin; Topoisomerase; Cytotoxic activity; Bioavailability
Keywords: توپویزومراز; DAPI; 4â²,6-diamidino-2-phenylindole; GUS; β-glucuronidase; PCNA; proliferating cell nuclear antigen; NOS; nopaline synthase; Chromosome condensation; Nicotiana tabaccum; Plant development; Synchronized BY-2 cell; Topoisomerase;
Keywords: توپویزومراز; Malaria; plDNA; Gyrase; Topoisomerase; Apicoplast; Fluoroquinolone
Keywords: توپویزومراز; ARNT; aryl hydrocarbon nuclear translocator; BCRP; breast cancer resistant protein; CAD; C-terminal activation domain; CAIX; carbonic anhydrase IX; CAV1; caveolin-1; ccRCC; clear cell renal cell carcinoma; CSC; cancer stem cells; DAG; diacylglycerol; DUSP
Keywords: توپویزومراز; Electrochemical immunosensor; Graphene-gold nanocomposites; Topoisomerase;
Keywords: توپویزومراز; Cycloprotoberberine; Topoisomerase; Structureâactivity relationship; Antiproliferative; Drug resistance;
Keywords: توپویزومراز; IAYPKPUQQHPMIC-LHBNBQMWSA-N; Tamoxifen derivatives; Breast cancer (MCF-7); Cervix adenocarcinoma (HeLa); Biphasic mesothelioma (MSTO-211H); Topoisomerase;
Keywords: توپویزومراز; AhR; aryl hydrocarbon receptor; AKT/PKB; protein kinase B; AOM; azoxymethane; AP; Acticoa power; AP-1; activator protein-1; ARE; antioxidant response element; CDK; cyclins-dpendent kinase; CLPr; cacao liquor proanthocyanidins; COX-2; cyclooxygenase-2; CYP
Castalagin and vescalagin purified from leaves of Syzygium samarangense (Blume) Merrill & L.M. Perry: Dual inhibitory activity against PARP1 and DNA topoisomerase II
Keywords: توپویزومراز; PARP1 inhibitor; Castalagin; Vescalagin; Olaparib; Topoisomerase; Syzygium samarangense; PARP; poly(ADP-ribose) polymerase; PAR; poly(ADP-ribose); PARylation; poly(ADP-ribosyl)ation; PARylate; poly(ADP-ribosyl)ate; ADP-ribose; ADPR; nicotinamide; Nam; CAS
Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors
Keywords: توپویزومراز; Topoisomerase; Histone deacetylase; Dual inhibitor; Drug design; Anticancer;
Nitric oxide reverses drug resistance by inhibiting ATPase activity of p-glycoprotein in human multi-drug resistant cancer cells
Keywords: توپویزومراز; Nitric Oxide; Multi-drug resistance; P-gp protein; Adriamycin; Taxol; Free radical; P-gp; P-glycoprotein 170; MDR; multi-drug resistance; ADR; Adriamycin; TX; taxol; ËNO; nitric oxide; topo; topoisomerase; PPNO; propylamine nonoate; DETNO; diethylenetria
Design, synthesis, and evaluation of novel N-1 fluoroquinolone derivatives: Probing for binding contact with the active site tyrosine of gyrase
Keywords: توپویزومراز; Bacterial resistance; Fluoroquinolone; DNA gyrase; Topoisomerase;
Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors
Keywords: توپویزومراز; Indolizinoquinolinedione; Topoisomerase; Inhibitor; DNA damage; Cytotoxicity;
Molecular discrimination of Bacillus cereus group species in foods (lettuce, spinach, and kimbap) using quantitative real-time PCR targeting groEL and gyrB
Keywords: توپویزومراز; Bacillus cereus; Chaperonin protein; Topoisomerase; Lettuce; Spinach; Kimbap;
Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1H-1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells
Keywords: توپویزومراز; Quinones; Triazole; Cancer; Anticancer agents; Molecular modelling; Topoisomerase;
Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors
Keywords: توپویزومراز; Antitubulin activity; Topoisomerase catalytic inhibitor; 1,3-Diarylisoquinoline; Suzuki coupling; Topoisomerase;
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2)
Keywords: توپویزومراز; Tyrosyl-DNA phosphodiesterase; DNA repair; Inhibitor; Furoquinolinedione; Topoisomerase;
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase
Keywords: توپویزومراز; Antimalarial; Gyrase; Mycobacterium tuberculosis; Pyronaridine; Repurposing; Topoisomerase; Tuberculosis; RNA polymerase;
R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome
Keywords: توپویزومراز; Primary immunodeficiency; Wiskott-Aldrich syndrome; X-linked thrombocytopenia; TH1/TH2 differentiation; R-loops; DNA damage; genomic instability; ChIP; Chromatin immunoprecipitation; DDR; DNA damage response; DRB; 5,6-Dichlorobenzimidazole-1-β-D-ribofura
Novel 3-fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV
Keywords: توپویزومراز; MRSA; NBTI; Antibacterial; Fluoroquinoline; Topoisomerase; Gyrase;
Erythro-austrobailignan-6 down-regulates HER2/EGFR/integrinβ3 expression via p38 activation in breast cancer
Keywords: توپویزومراز; Breast cancer; Erythro-austrobailignan-6, p38; Caspase-3; Topoisomerase; EGFR; EA6; Erythro-Austrobailignan-6; JNK; c-Jun N-terminal kinase; EGFR; epidermal growth factor receptor; SC; Saururus chinensis; CDK-4; cycle dependent protein kinase-4; HER2; hum
Nitric oxide inhibits ATPase activity and induces resistance to topoisomerase II-poisons in human MCF-7 breast tumor cells
Keywords: توپویزومراز; Topoisomerase; Nitric oxide; ATPase inhibition; m-AMSA; XK469; Resistance;
Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples
Keywords: توپویزومراز; HCV; Nucleic acid; Gold nanoparticles; RNA detection; DNA repair; Topoisomerase;
A novel topoisomerase 2a inhibitor, cryptotanshinone, suppresses the growth of PC3 cells without apparent cytotoxicity
Keywords: توپویزومراز; topo; topoisomerase; VP-16; etoposide; AChE; acetylcholinesterase; STAT 3; signal transducer and activator of transcription 3; AMPK; AMP-activated protein kinase; MTT; 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide; FBS; fetal bovine serum; H
Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I
Keywords: توپویزومراز; Bayesian models; Collaborative drug discovery tuberculosis database; Docking; Function class fingerprints; Homology model; Mycobacterium tuberculosis; Topoisomerase; Tuberculosis;
Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite
Keywords: توپویزومراز; Bis-dioxopiperazine; Cardioprotection; JR-311; Structure-activity relationship; Topoisomerase;
Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition
Keywords: توپویزومراز; Naphthoquinones; Synthesis; Regioselective; Anticancer; Topoisomerase; Acute oral toxicity;
Global developmental delay and intellectual disability associated with a de novo TOP2B mutation
Keywords: توپویزومراز; Whole-exome sequencing (WES); TOP2B; Topoisomerase; UBE3a; E3 ubiquitin ligase;
Triggering autophagic cell death with a di-manganese(II) developmental therapeutic
Keywords: توپویزومراز; γH2AX; phosphorylated H2AX histone; caspase; cysteine-dependent asparate-specific proteases CAT, catalase; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; Dox; doxorubicin; DSB; double strand breaks; LC-3; microtubule associated protein 1 light weight c
Identification of potent virtual leads and ADME prediction of isoxazolidine podophyllotoxin derivatives as topoisomerase II and tubulin inhibitors
Keywords: توپویزومراز; Podophyllotoxin; Molecular docking; Topoisomerase; Tubulin; ADMET;
Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells
Keywords: توپویزومراز; TPT; Topotecan; AA; Ascorbic Acid; Topo; Topoisomerase; ESR; Electron Spin Resonance; HRP; Horseradish Peroxidase; GSH; Reduced Glutathione; GSSG; Oxidized Glutathione; DMPO; 5,5-Dimethyl Pyrroline-1-N-oxide; ROS; Reactive Oxygen Species; Topotecan; Ascor
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents
Keywords: توپویزومراز; DDQ; 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; FID; fluorescence intercalator displacement; G4; G-quadruplex; TO; thiazole orange; Topo; topoisomerase; Indenocinnoline derivatives; Intercalating agents; Topoisomerase inhibitors; Antitumor agents; G-quadr
Topoisomerase I inhibition and DNA cleavage by zinc, copper, and nickel derivatives of 2-[2-bromoethyliminomethyl]-4-[ethoxymethyl]phenol complexes exhibiting anti-proliferation and anti-metastasis activity
Keywords: توپویزومراز; Zinc; Copper; Nickel; Schiff base; Topoisomerase; DNA
Replacement of cardiotoxic aminopiperidine linker with piperazine moiety reduces cardiotoxicity? Mycobacterium tuberculosis novel bacterial topoisomerase inhibitors
Keywords: توپویزومراز; DNA gyrase; Topoisomerase; Tuberculosis; 1,5-Naphthyridin-2(1H)-one; zERG toxicity
Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure–activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor
Keywords: توپویزومراز; Pyrazoline derivatives; Antiproliferative activity; Topoisomerase; ATP-competitive inhibitor
A new light on the meiotic DSB catalytic complex
Keywords: توپویزومراز; Topoisomerase; Meiosis; Recombination; Double strand break; SPO11;
Thiazole-based nitrogen mustards: Design, synthesis, spectroscopic studies, DFT calculation, molecular docking, and antiproliferative activity against selected human cancer cell lines
Keywords: توپویزومراز; Antiproliferative activity; Thiazole; Nitrogen mustard; DFT calculations; Nucleobases; Topoisomerase
Synthesis and biological evaluation of imidazopyridinyl-1,3,4-oxadiazole conjugates as apoptosis inducers and topoisomerase IIα inhibitors
Keywords: توپویزومراز; Imidazopyridine; Oxadiazole; Cytotoxicity; Topoisomerase; Molecular docking;
Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents
Keywords: توپویزومراز; Pyrazole; Claisen-Schmidt condensation; Michael addition; Cytotoxicity; Topoisomerase; Docking;
Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents
Keywords: توپویزومراز; Quinolone; Benzimidazole; Anti-MRSA; DNA; Topoisomerase;
Tyrosyl-DNA phosphodiesterase inhibitors: Progress and potential
Keywords: توپویزومراز; DNA repair; Topoisomerase; Camptothecin; Top1 inhibitors; Top2 inhibitors; Tyrosyl-DNA phosphodiesterase; Tdp1; Tdp2; Tdp1 inhibitors; Tdp2 inhibitors; Indenoisoquinolines;
New spiro-acridines: DNA interaction, antiproliferative activity and inhibition of human DNA topoisomerases
Keywords: توپویزومراز; Spiro-acridine; DNA-binding; Topoisomerase;
Trypanotoxic activity of thiosemicarbazone iron chelators
Keywords: توپویزومراز; Trypanosoma brucei; Sleeping sickness; Topoisomerase; Thiosemicarbazone iron chelators;
Characterization of the interaction between Escherichia coli topoisomerase IV E subunit and an ATP competitive inhibitor
Keywords: توپویزومراز; Antibacterial agents; 19F NMR; Drug design; Docking; Topoisomerase;
NMR structural characterization of the N-terminal active domain of the gyrase B subunit from Pseudomonas aeruginosa and its complex with an inhibitor
Keywords: توپویزومراز; NMR; Drug discovery; Topoisomerase; Gyrase B; Structure-based drug design;