دانلود مقالات ISI درباره Trypanosoma Brucei + ترجمه فارسی

The ins and outs of phosphatidylethanolamine synthesis in Trypanosoma brucei

Keywords: PE; phosphatidylethanolamine; PC; phosphatidylcholine; PS; phosphatidylserine; PI; phosphatidylinositol; SM; sphingomyelin; IPC; inositolphosphoryl ceramide; EPC; ethanolaminephosphoryl ceramide; EPT; ethanolamine phosphotransferase; CEPT; choline/ethanol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The Trypanosoma brucei telomerase RNA (TER) homologue binds core proteins of the C/D snoRNA family

Keywords: Telomerase; TER RNA; C/D snoRNA; Trans-splicing of non-coding RNAs; Trypanosoma brucei

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy

Keywords: Trypanosoma brucei; endocytosis; suramin; trypanolytic factor; drug delivery

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing

Keywords: Aurora kinase; Trypanosoma brucei; TbAUK1; Cell cycle; Neglected disease; Target repurposing; Sleeping sicknessHAT, human African trypanosomiasis; BF, bloodstream form T. brucei; cAMP, cyclic adenosine monophosphateCZJFNTGVBHZXHP-NWEAHGIASA-N

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Chromatin immunoprecipitation and microarray analysis reveal that TFIIB occupies the SL RNA gene promoter region in Trypanosoma brucei chromosomes

Keywords: Trypanosomes; RNA synthesis; SL RNA genes; Trypanosoma brucei; Chromatin immunoprecipitation; TFIIB

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosoma brucei solanesyl-diphosphate synthase localizes to the mitochondrion

Keywords: TbSPPS; Trypanosoma brucei solanesyl-diphosphate synthase; UQ; ubiquinone; ORF; open reading frame; FITC; fluorescein isothiocyanate; Trypanosoma brucei; Sleeping sickness; Ubiquinone; Solanesyl-diphosphate synthase; Digitonin permeabilization; In situ ta

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and antitrypanosomal activity of new 6,6,7-trisubstituted thiopyrano[2,3-d][1,3]thiazoles

Keywords: Human African trypanosomiasis; Thiopyrano[2,3-d][1,3]thiazoles; Trypanosoma brucei; Antitrypanosomal activity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

VSG 117 gene is conservatively present and early expressed in Trypanosma evansi YNB stock

Keywords: Trypanosoma brucei; Trypanosoma evansi; Antigenic variation; VSG 117; Gene conversion; Genetic exchange;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei

Keywords: HAT; human African trypanosomiasis; VSG; variant surface glycoprotein; HDAC; histone deacetylases; DAC; deacetylases; SAR; Structure-activity relationship; Anti-parasitic activity; Trypanosoma brucei; Histone deacetylase inhibitors; Hydroxamic acids;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation and spatial organization of PCNA in Trypanosoma brucei

Keywords: PCNA; Replication; S phase marker; Cell cycle regulation; Trypanosoma brucei;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosoma brucei: Inhibition of acetyl-CoA carboxylase by haloxyfop

Keywords: ACC; acetyl-CoA carboxylase; BCCP; biotin-carboxyl carrier protein; BF; bloodstream form trypanosome; CT; carboxyl-transferase; DIMs; cyclohexanediones; DMSO; dimethyl sulfoxide; ELO; microsomal elongase; FAME; fatty acid methyl ester; FAS; fatty acid syn

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Terminal galactosylation of glycoconjugates in Plasmodium falciparum asexual blood stages and Trypanosoma brucei bloodstream trypomastigotes

Keywords: Bandeirea (Griffonia) simplicifolia B4 lectin 1; Galactosylation; Glycoconjugate; Plasmodium falciparum; Trypanosoma brucei;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosoma brucei transferrin receptor can bind C-lobe and N-lobe fragments of transferrin

Keywords: Con A; concanavalin A; DAPI; 4,6-diamidino-2-phenylindole; ESAG; expression site-associated gene; hTfR; human transferrin receptor; Lf; lactoferrin; TbTfR; T. brucei transferrin receptor; Tf; transferrin; VSG; variant surface glycoprotein; Z-FA-DMK; benzy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic characterization of Trypanosoma brucei circulating in domestic animals of the Fontem sleeping sickness of Cameroon

Keywords: Microsatellite markers; Sleeping sickness; Trypanosoma brucei; Multiple genotypes

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Development of an efficient in vitro transcription system for bloodstream form Trypanosoma brucei reveals life cycle-independent functionality of class I transcription factor A

Keywords: Transcription; In vitro system; SL RNA gene promoter; RNA polymerases I and II; Trypanosoma brucei;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

TbENF is an essential TbTFIIB-interacting trypanosomatid-specific factor

Keywords: RNAP; RNA polymerase; SL; spliced leader; ENF; Essential Nuclear Factor; TAP; Tandem Affinity Purification; RNAi; RNA interference; Trypanosoma brucei; TFIIB-interacting protein; Transcription; DNA-binding protein;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Quinol derivatives as potential trypanocidal agents

Keywords: Inhibitors; Medicinal chemistry; Trypanosoma brucei; P2 transporter; Quinols;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L

Keywords: E64; (l-trans-Epoxysuccinyl-l-leucylamido-(4-guanidino)butane); Z-FR-MCA; benzyloxycarbonyl-phenylalanyl-arginine-7-amino-4-methylcoumarin hydrochloride; Z-VLR-MCA; benzyloxycarbonyl-valine-leucine-arginine-7-amino-4-methylcoumarin; GAG; glycosaminogl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Extra-glycosomal localisation of Trypanosoma brucei hexokinase 2

Keywords: Trypanosoma brucei; Hexokinase; Flagellum; Glycosome; Glycolysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of a Trypanosoma brucei Alkb homolog capable of repairing alkylated DNA

Keywords: αKG; α-ketoglutarate; MMS; methyl methanesulfonate; ODPA; ortho-phenylenediamine; TbABH; AlkB homolog from Trypanosoma brucei; Trypanosoma brucei; DNA repair; Oxidative demethylation; α-Ketoglutarate; Ferrous ion;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei

Keywords: Flagellum; Trypanosoma brucei; Kinetoplastid; Paraflagellar rod; Cryo-electron tomography; Frozen hydrated sections;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of Trypanosoma brucei leucyl-tRNA synthetase inhibitors by pharmacophore- and docking-based virtual screening and synthesis

Keywords: Human African trypanosomiasis; Trypanosoma brucei; Leucyl-tRNA synthetase; Virtual screening; Pharmacophore; Docking

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents

Keywords: AP; apurinic/apyrimidinic; TBAPE1; Trypanosoma brucei AP endonuclease 1; LMAP; Leishmania major AP endonuclease; exoIII; exonuclease III; endoIV; endonuclease IV; OGG1; 8-oxoguanine DNA glycosylase 1; NTH1; endonuclease III; BSD; blasticidin S transferase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

A role for the vesicle-associated tubulin binding protein ARL6 (BBS3) in flagellum extension in Trypanosoma brucei

Keywords: Arf; ADP-ribosylation factor; Arl; ADP-ribosylation factor-like; Arl6ip; Arl6 interacting protein; BBS; Bardet-Biedl syndrome; BBS1; Bardet-Biedl syndrome 1 protein; BSF; bloodstream form; ConA; Concanavalin A; GEF; guanine nucleotide exchange factor;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

A Trypanosoma brucei Protein Required for Maintenance of the Flagellum Attachment Zone and Flagellar Pocket ER Domains

Keywords: ERES; ER exit sites; FAZ; flagellum attachment zone; FAZ ER; flagellum attachment zone-associated endoplasmic reticulum; MSP; major sperm protein; MtQ; microtubule quartet; PFR; paraflagellar rod; VAP; VAMP-associated protein; Cellular electron tomography

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosomes lacking uracil-DNA glycosylase are hypersensitive to antifolates and present a mutator phenotype

Keywords: Trypanosoma brucei; Uracil-DNA glycosylase; Methotrexate; Uracil; Genome stability; Infectivity

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei

Keywords: Sterols; Trypanosoma brucei; RNA interference; Squalene synthase; Squalene epoxidase; Sterol methyl transferase;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanocidal activity of peptidyl vinyl ester derivatives selective for inhibition of mammalian proteasome trypsin-like activity

Keywords: Trypanosoma brucei; Sleeping sickness; Proteasome; Vinyl ester tripeptides;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

SAR of 2-amino and 2,4-diamino pyrimidines with in vivo efficacy against Trypanosoma brucei

Keywords: Trypanosoma brucei; Human african trypanosomiasis; 2,4-Diamino pyrimidines

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Short communicationThe VSG C-terminal domain is inaccessible to antibodies on live trypanosomes

Keywords: Trypanosome; VSG; Trypanosoma brucei; Cell surface; Antibody;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei

Keywords: Fatty-acid desaturase; Drug target; Trypanosoma brucei; Thiastearic acid; Isoxyl; RNA interference;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Quercetin, a fluorescent bioflavanoid, inhibits Trypanosoma brucei hexokinase 1

Keywords: Trypanosoma brucei; Hexokinase; Quercetin; Glycolysis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Trypanosoma brucei s.l.: Microsatellite markers revealed high level of multiple genotypes in the mid-guts of wild tsetse flies of the Fontem sleeping sickness focus of Cameroon

Keywords: Microsatellite markers; Sleeping sickness; Trypanosoma brucei; Tsetse fly mid-gut; Multiple genotypes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase

Keywords: βHBDH; beta-hydroxybutyrate dehydrogenase; Tb; Trypanosoma brucei; RNAi; RNA interference; Trypanosoma brucei; Hydroxybutyrate dehydrogenase; Cofactor preference; Short dehydrogenase/reductase superfamily; Energy metabolism;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Transketolase in Trypanosoma brucei

Keywords: TKT; transketolase; PPP; pentose phosphate pathway; ENO; enolase; ALD; aldolase; 6-PGDH; 6-phosphogluconate dehydrogenase; Xu5P; xylulose 5-phosphate; R5P; ribose 5-phosphate; S7P; sedoheptulose 7-phosphate; Trypanosoma brucei; Transketolase; Pentose phos

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Trypanosoma evansi: Identification and characterization of a variant surface glycoprotein lacking cysteine residues in its C-terminal domain

Keywords: Trypanosoma brucei; Trypanosoma evansi; Antigenic variation; Variant surface glycoprotein; C-terminal domain; Cysteine residues

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Trypanosoma brucei: Immunisation with plasmid DNA encoding invariant surface glycoprotein gene is able to induce partial protection in experimental African trypanosomiasis

Keywords: Trypanosoma brucei; African trypanosomiasis; DNA vaccine; CpG DNA; Invariant surface glycoprotein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Human African trypanosomiasis: a review of non-endemic cases in the past 20 years

Keywords: Sleeping sickness; African trypanosomiasis; Trypanosoma brucei; T. b. gambiense; T. b. rhodesiense; Non-endemic; Trypanosome; HAT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Transcription by the multifunctional RNA polymerase I in Trypanosoma brucei functions independently of RPB7

Keywords: RNA polymerase I; RPB7; RPA43; Transcription; Trypanosoma brucei;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase

Keywords: Aminoacyl-tRNA synthetase; Cryptosporidium; Trypanosoma brucei; Entamoeba; Giardia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response

Keywords: Trypanosoma cruzi; DNA repair; MSH2; Oxidative stress; Trypanosoma brucei;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Leishmania amazonensis META2 protein confers protection against heat shock and oxidative stress

Keywords: Leishmania amazonensis; Metacyclogenesis; Oxidative stress; Heat shock; Calpain-like; Trypanosoma brucei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure–activity relationships with Trypanosoma brucei GSK-3

Keywords: Glycogen synthase kinase-3; Leishmania spp.; Trypanosoma brucei; African sleeping sickness; Drug development; Protein kinase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

In silico identification of novel protective VSG antigens expressed by Trypanosoma brucei and an effort for designing a highly immunogenic DNA vaccine using IL-12 as adjuvant

Keywords: Trypanosoma brucei; Antigenic variability; Vaccine candidates; African trypanosomiasis; Immunoinformatics

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei

Keywords: Trypanosoma brucei; BRCA2; RAD51; Homologous recombination; DNA repair; Methyl methane sulfonate; Yeast 2-hybrid analysis; Aptamer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

A tryparedoxin-dependent peroxidase protects African trypanosomes from membrane damage

Keywords: T. brucei; Trypanosoma brucei; L. major; Leishmania major; wt; wild-type; Px; non-selenium glutathione peroxidase-type tryparedoxin peroxidase; TXNPx; 2-Cys-peroxiredoxin-type tryparedoxin peroxidase; TR; trypanothione reductase; Tpx; tryparedoxin; T(SH)2

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Glycotyping of Trypanosoma brucei variant surface glycoprotein MITat1.8

Keywords: Trypanosoma brucei; N-linked oligosaccharides; N-glycosylation; Glycosylphosphatidylinositol; GPI; Mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei

Keywords: BDF; bromodomain-containing proteins; ChIP; chromatin immunoprecipitation; ChIP-seq; ChIP-sequencing; SSR; strand-switch regions; TSS; transcription start sites; Trypanosoma brucei; Histone modification; Transcription regulation; Chromatin immunoprecipita

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Cell-cycle synchronisation of bloodstream forms of Trypanosoma brucei using Vybrant DyeCycle Violet-based sorting

Keywords: Trypanosoma brucei; Cell-cycle; Vybrant DyeCycle Violet; Flow cytometry; Synchronisation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Short communicationMyristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects

Keywords: Arf; ADP-ribosylation factor; Arl; ADP-ribosylation factor-like; BSF; bloodstream form; ConA; concanavalin A; NMT; myristoyl-CoA:protein N-myristoyltransferase; RNAi; RNA interference; T. brucei; Trypanosoma brucei; VSG; variant surface glycoprotein; Myri

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه