دانلود مقالات ISI درباره Vpa + ترجمه فارسی

Valproate attenuates the proteinuria, podocyte and renal injury by facilitating autophagy and inactivation of NF-κB/iNOS signaling in diabetic rat

Keywords: Autophagy; HDAC inhibitor; Diabetic nephropathy; NF-κB/iNOS signaling; Proteinuria; Sodium valproate; Ac-H3/Ac-H4; acetylated histone H3/H4; CaB; calbindin; CaM; calmodulin; DN; diabetic nephropathy; FITC; fluorescein isothiocyanate; HDACs; histone deace

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

A novel centrosome and microtubules associated subcellular localization of Nogo-A: Implications for neuronal development

Keywords: CNS; central nervous system; DRG; dorsal root ganglia; MTOC; microtubule organizing center; SD; Sprague-Dawley; UD; undifferentiated; VPA; valproic acid; Nogo-A; Centrosome; Microtubules; Neuro2A; Neuronal development;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewThe fetal safety of Levetiracetam: A systematic review

Keywords: AEDs; antiepileptic drugs; GMDS; Griffiths Mental Development Scale; LEV; Levetiracetam; LTG; lamotrigine; MCM; major congenital malformation; NAARP; North American Pregnancy Antiepilepsy Registry; TPM; topiramate; VPA; valproic acid; Pregnancy; Levetirac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts

Keywords: VPA; valproic acid/sodium valproate; mtDNA; mitochondrial DNA; POLG; polymerase γ; AHS; Alpers-Huttenlocher syndrome (OMIM: 203700); MIRAS; mitochondrial recessive ataxia syndrome; SANDO; sensory ataxia, neuropathy, dysarthria, ophthalmoplegia (OMIM: 6

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The effects of selected inhibitors of histone modifying enzyme on C6 glioma cells

Keywords: 3DZNep; 3-deazaneplanocin; GBM; glioblastoma; HDACs; histone deacetylases; TSA; trichostatin A; VPA; valproic acid; Glioma; Epigenetics; Histone modification; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Pentyl-4-yn-VPA, a histone deacetylase inhibitor, ameliorates deficits in social behavior and cognition in a rodent model of autism spectrum disorders

Keywords: Social cognition; SAHA; VPA; H3K9ac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ghrelin inhibits BSCB disruption/hemorrhage by attenuating MMP-9 and SUR1/TrpM4 expression and activation after spinal cord injury

Keywords: BBB; blood-brain barrier; BSCB; blood spinal cord barrier; COX-2; cyclooxygenase-2; Ghrelin receptor; GHS-R1a; iNOS; inducible nitric oxide synthase; i.p; intraperitoneal; IL; interleukin; MMP; matrix metalloprotease; SCI; spinal cord injury; SUR1; sulfon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid enhances Oct4 promoter activity through PI3K/Akt/mTOR pathway activated nuclear receptors

Keywords: Muscle; Oct4; Nuclear receptor; iPSC; VPA; Akt;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MKP-1 in murine brain microvascular endothelial cells

Keywords: AREs; AU-rich elements; BBB; blood-brain barrier; C/EBPβ; CCAAT enhancer binding protein beta; CNS; central nervous system; COX-2; cyclooxygenase-2; HAT; histone acetyltransferase; HDAC; histone deacetylase; JNK; c-Jun N-terminal kinase; LPS; lipopolys

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroepigenetics of stress

Keywords: 5-HT; Serotonin; ACTH; adrenocorticotropic hormone; AVP; arginine-vasopressin; BDNF; brain-derived neurotrophic factor; BLA; basolateral amygdala; COMT; catechol-O-methyltransferase; CpG; cytosine-guanine dinucleotides; CRH; corticotropin-releasing hormon

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid increases NO production via the SH-PTP1-CDK5-eNOS-Ser116 signaling cascade in endothelial cells and mice

Keywords: eNOS; endothelial nitric oxide synthase; CDK5; cyclin-dependent kinase 5; JNK; c-Jun N-terminal kinase; Abl; Abelson kinase; SH-PTP; SH2 domain-containing protein tyrosine phosphatase; VPA; valproic acid; HDAC; histone deacetylase; HUVEC; human umbilical

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2014 سفارش ترجمه

Levetiracetam but not valproate inhibits function of CD8+ T lymphocytes

Keywords: Levetiracetam; Valproate; CD8+ T lymphocytes; Apoptosis; SV2A; Perforin; CEF; CTL-CEF-Class I peptide pool “Plus”; CFSE; carboxyl fluorescein succinimidyl ester; IFNγ; interferon gamma; IL; interleukin; IQR; interquartile range; LEV; levetiracetam; P

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Immunoglobulin-responsive refractory epilepsy - 3 cases with a similar EEG pattern

Keywords: ACTH; adrenocorticotrophic hormone; AEDs; antiepileptic drugs; CSF; cerebrospinal fluid; CT; computer tomography; DZP; diazepam; EEG; electroencephalogram; FDG-PET; flurodecarboxyglucose - positron emission tomography; GAD; glutamic acid decarboxylase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The alteration of hypoxia inducible factor-1 (HIF-1) and its target genes in mood disorder patients

Keywords: HIF-1; Hypoxia inducible factor-1; VEGF; vascular endothelial growth factor; MDD; major depressive disorder; BPD; bipolar disorder; BDNF; brain-derived neurotrophic factor; GDNF; glial cell line-derived neurotrophic factor; EPO; erythropoietin; GLUT1,3; g

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Therapeutic concentrations of valproate but not amitriptyline increase neuropeptide Y (NPY) expression in the human SH-SY5Y neuroblastoma cell line

Keywords: AMI; amitriptyline; AP-1; activator protein 1; Atoh1; atonal homolog-1; BDNF; brain-derived neurotrophic factor; bp; base pair; CREB; cAMP response element-binding protein; Cp; crossing point; ERK; extracellular signal-regulated kinase; DMEM/F12 Ham; Dulb

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Vagus nerve stimulation for drug-resistant Epilepsia Partialis Continua: Report of four cases

Keywords: EPC; Epilepsia Partialis Continua; VNS; vagus nerve stimulation; RE; Rasmussen's encephalitis; ACDs; anticonvulsant drugs; SE; status epilepticus; MDZ; midazolam; CBZ; carbamazepine; OXC; oxcarbamazepine; TPM; topiramate; LVT; leviracetam; VPA; valproic a

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic upregulation of Bak by ZBP-89 inhibits the growth of hepatocellular carcinoma

Keywords: 5-Aza-dC; 5-aza-2′-deoxycytidine; ChIP; chromatin immunoprecipitation; Co-IP; co-immunoprecipitation; DNMT; DNA methyltransferase; HCC; hepatocellular carcinoma; HDAC; histone deacetylase; MeCP2; methyl-CpG-binding protein 2; MIHA; immortalized non-tumo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The novel insulin resistance parameters RBP4 and GLP-1 in patients treated with valproic acid: Just a sidestep?

Keywords: VPA; Weight; Insulin resistance; GLP-1; RBP4

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Self reported adverse effects of mono and polytherapy for epilepsy

Keywords: AED; anti epileptic drug; AE; adverse effect; CBZ; Carbamazepine; LTG; Lamotrigine; LEV; Levetiracetam; PHT; Phenytoin; VPA; Valproate; LAEP; Liverpool Adverse Event Profile; CLE; cryptogenic localisation related epilepsy; SLE; symptomatic localisation re

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Total steroidal alkaloids from Veratrum patulum L. Inhibit platelet aggregation, thrombi formation and decrease bleeding time in rats

Keywords: VpA; Veratrum patulum L. (Liliaceae) total steroidal alkaloids; OT; occlusion time; Veratrum patulum L.; Steroidal alkaloids; Antithrombotic; Antiplatelet; Bleeding time;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of vitamin U (S-methyl methionine sulphonium chloride) on valproic acid induced liver injury in rats

Keywords: Vit U; vitamin U; VPA; valproic acid; AEDs; antiepileptic drugs; GSH; reduced glutathione; LPO; lipid peroxidation; AST; aspartate transaminase; ALT; alanine transaminase; ALP; alkaline phosphatase; LDH; lactate dehydrogenase; MPO; myeloperoxidase; SDH; s

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Valproate induces epigenetic modifications in lymphomonocytes from epileptic patients

Keywords: CNS; central nervous system; GABA; gamma-aminobutyric acid; GAD; glutamic acid decarboxylase; H3; histone 3; HDAC; histone deacetylase; PBMC; peripheral blood mononuclear cells; TSA; trichostatin-A; VPA; valproate; DNA methylation; Epimutations; Histone a

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of valproic acid on the expression of trophic factors in human bone marrow mesenchymal stromal cells

Keywords: BM-MSCs; bone marrow-mesenchymal stromal cells; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence-activated cell sorting; FBS; fetal bovine serum; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, a tetrazole; PBS; phosphate-bu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells

Keywords: BD; bipolar disorder; Li; lithium; VPA; valproate; CBZ; carbamazepine; LTG; lamotrigine; DG; dentate gyrus; STS; staurosporine; ADP; adult rat dentate gyrus-derived neural precursor cell; Apoptosis; Hippocampus; Dentate gyrus; Adult neurogenesis; Bcl-2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Differential regulation of PML-RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1

Keywords: APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; HDACi; histone deacetylase inhibitor; PML-RARα; promyelocytic leukemia-retinoic acid receptor α; SIAH; seven in absentia homolog; TRIAD1; two RING fingers and DRIL (double RING finger

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Physical Activity, Fitness, and Serum Leptin Concentrations in Adolescents

Keywords: FFM; Fat free mass; HELENA-CSS; Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study; HOMA; Homeostasis model assessment; MPA; Moderate physical activity; MET; Metabolic equivalent; MVPA; Moderate to vigorous physical activity; PA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice

Keywords: Ketogenic diet; Pentylenetetrazole; Maximal electroshock; 6-Hz seizure test; Seizure thresholds tests; Brain concentrations; AEDs; antiepileptic drugs; CA; caprylic acid; KD; ketogenic diet; MCT; medium-chain triglycerides; MES; maximal electroshock; MEST

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway

Keywords: Nestin; GSK-3β; β-Catenin; Macrocephaly; Autism; GSK-3β; glycogen synthase kinase 3 beta; β-catenin; cadherin-associated protein-β; NPCs; neural progenitor cells; VPA; valproic acid; FACS; fluorescence-activated cell sorting; VZ; ventricular zone; SV

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

A New Device for Simultaneous Measurement of Pelvic Floor Muscle Activity and Vaginal Blood Flow: A Test in a Nonclinical Sample

Keywords: Pelvic Floor; Vaginal Surface EMG; Sexual Arousal; VPA; Dyspareunia

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Chromatin-modifying agents in anti-cancer therapy

Keywords: Epigenetic inhibitors; HDAC; DNMT; Anti-cancer therapy; Clinical trials; Combinatory treatments; AML; acute myeloid leukemia; AZA; 5-azacytidine; CMA; chromatin-modifying agent; CML; chronic myeloid leukemia; CMML; chronic myelomonocytic leukemia; CTCL; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of PTK6, via RNA Sequencing Analysis, as a Suppressor of Esophageal Squamous Cell Carcinoma

Keywords: Gene Expression; Epigenetic Regulation; Cell Cycle; Signal Transduction; ChIP; chromatin immunoprecipitation; ESCC; esophageal squamous cell carcinoma; GO; Gene Otology; GSK; glycogen synthase kinase; IHC; immunohistochemistry; NT; nontumor; NTC; nontarge

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2012 سفارش ترجمه

Hyperglycemia and Diabetes Mellitus in Children with Pancreatitis

Keywords: ADA; American Diabetes Association; AP; Acute pancreatitis; ARP; Acute recurrent pancreatitis; BMI; Body mass index; DM; Diabetes mellitus; VPA; Valproic acid;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cells

Keywords: Li; lithium; VPA; valproate; CBZ; carbamazepine; LTG; lamotrigine; DG; dentate gyrus; ADP; adult rat DG-derived neural precursor cell; DEX; dexamethasone; STS; staurosporine; RA; retinoic acid; PHT; phenytoin; TUNEL; terminal deoxynucleotidyl transferase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleNew insights on the mechanisms of valproate-induced hyperammonemia: Inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA

Keywords: Hyperammonemia; Urea cycle; Drug-induced liver injury; Drug-induced hepatotoxicity; N-acetylglutamate synthase; N-acetylglutamate; Valproate; Valproyl-CoA; VPA; valproic acid or 2-n-propylpentanoic acid; VP-CoA; valproyl-CoA; NAG; N-acetylglutamate; NAGS;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Valproic acid restores ERα and antiestrogen sensitivity to ERα-negative breast cancer cells

Keywords: Breast cancer; ERα; HDI; VPA; Antiestrogen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Modeling the impacts of policy measures to prevent import of illegal wood and wood products

Keywords: FLEGT; VPA; Forest sector modeling; EFI-GTM; Partial equilibrium model

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation

Keywords: mouse; vomeronasal organ; VNO; neurogenesis; epigenetic regulation; AOB; accessory olfactory bulb; HDAC; histone deacetylase; IPA; ingenuity pathway analysis; MUP; mouse urinary protein; OMP; olfactory marker protein; PBS; phosphate buffered saline; PCR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat

Keywords: AED; anti-epileptic drug; VPA; valproaic acid; CBZ; carbamazepine; CSRSs; chronic spontaneous recurrent seizures; CPS; complex partial seizure; TD50; dose producing toxicity in 50% of subjects; Posttraumatic epilepsy; Neocortical epilepsy; Trauma; Screeni

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2010 سفارش ترجمه

Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions

Keywords: VPA; HDAC inhibitor; Histone acetylation; BDNF; GABAA receptor; GAD;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice

Keywords: valproate; neuroligin; neurexin; genetics of autism; animal model; in utero challenge; ASD; autism spectrum disorder; CA; cornu ammonis; CB; cerebellum; CNV; copy number variation; CON; control (mice); DG; dentate gyrus; DPM; disintegrations per minute; M

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Research ReportValproic acid regulates catecholaminergic pathways by concentration-dependent threshold effects on TH mRNA synthesis and degradation

Keywords: SCFA; short chain fatty acid; SB; sodium butyrate; VPA; valproic acid; TH; tyrosine hydroxylase; PC12; pheochromocytoma cell line; mRNA; messenger RNA; rRNA; ribosomal RNA; CREB; cAMP response element binding protein; AP-1; activator protein; DBH; dopamin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Interaction of speech and script in human auditory cortex: Insights from neuro-imaging and effective connectivity

Keywords: fMRI; Auditory cortex; Audiovisual; Speech; Script; Multisensory integration; Granger causality mapping; A1; primary auditory cortex; aSTP; anterior superior temporal plane; BOLD; Blood Oxygen Level Dependent; CSEM; covariance structural equation modeling

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Chemically distinct HDAC inhibitors prevent adipose conversion of subcutaneous human white preadipocytes at an early stage of the differentiation program

Keywords: C/EBPα; CCAAT/enhancer-binding protein-α; FABP4/aP2; adipose specific fatty acid binding protein; FCS; foetal calf serum; GPDH; Sn-glycerol-3-phosphate dehydrogenase; HBSS; Hank's balanced salt solution; HDAC; histone deacetylase; HDACi; histone deacety

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

A Rationally Designed Histone Deacetylase Inhibitor with Distinct Antitumor Activity against Ovarian Cancer

Keywords: HDAC; histone deacetylase; HDACI; histone deacetylase inhibitor; SAHA; suberoylanilide hydroxamic acid; VPA; valproic acid; AE1/AE3; a mixture of two monoclonal antibodies (AE1 and AE3), with broad specificity against cytokeratins; NOSE; normal ovarian su

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Adiponectin receptor R1 is upregulated by valproic acid but not by topiramate in human hepatoma cell line, HepG2

Keywords: Adiponectin receptor; VPA; Insulin resistance

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Valproic Acid Induces Notch1 Signaling in Small Cell Lung Cancer Cells 1

Keywords: valproic acid; VPA; histone deacetylase inhibitors; small cell lung cancer; neuroendocrine tumors; Notch1; achaete-scute homologue-1; ASCL-1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes

Keywords: VPA; valproic acid or 2-n-propyl-pentanoic acid; Δ4-VPA; Δ4-valproic acid or 2-n-propyl-4-pentenoic acid; CoA; coenzyme A; VP-CoA; valproyl-CoA; Δ4-VP-CoA; Δ4-valproyl-CoA; ISMV; inverted submitochondrial vesicles; IMM; inner mitochondrial membrane; U

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of valproic acid treatment on body composition, leptin and the soluble leptin receptor in epileptic children

Keywords: VPA; Weight; Soluble leptin receptor; sOB-R/leptin ratio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and ΔFosB expression in the striatum and locomotor sensitization in mice

Keywords: histone deacetylase; cAMP responsive element binding protein; chromatin immunoprecipitation; butyric acid; valproic acid; amphetamine; AcH4; acetylated H4; BA; butyric acid; B+S; butyric acid+saline; ChIP; chromatin immunoprecipitation; co-IP; co-immunopr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium

Keywords: 2D electrophoresis; Alzheimer's disease; Biomarkers; Glycogen synthase kinase-3; GSK-3; Histone deacetylase inhibitor; HDAC; PBMC; Proteomics; qRT-PCR; Valproic acid; VPA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه