Comparison of 2 maintenance doses (100 μg vs 200 μg) in Hymenoptera venom immunotherapy: influence of the maintenance dose on the immunologic response

Increasing the monthly maintenance dose to 200 μg results in a greater degree of change in venom specific IgE antibody levels and skin test sensitivity than when maintaining a 100-μg dose. Our data strengthen those of previous clinical studies showing the usefulness of a 200-μg maintenance dose in the case of clinical failure of a 100-μg dose.