Association of change in clinical status and change in the percentage of the CD4+CD26− lymphocyte population in patients with Sézary syndrome

Flow cytometry assays of patients' blood and, in particular, measurement of the CD4+CD26− population of lymphocytes over time may be a valuable tool for monitoring patients with Sézary syndrome. There exist varying configurations of CD26 T lymphocytes that may cause differences in standards for what is considered positive and negative between observers. Further prospective analysis involving larger groups of patients is recommended.