کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
101690 161288 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hair testing in postmortem diagnosis of substance abuse: An unusual case of slow-release oral morphine abuse in an adolescent
ترجمه فارسی عنوان
تست مو در تشخیص سوء مصرف مواد پس از مرگ: یک مورد غیرمعمول از سوء مصرف داروهای مورفین خوراکی در نوجوانی
کلمات کلیدی
مورفین خوراکی با رهش آهسته ؛ مصرف بیش از حد؛ نوجوانان؛ اعتیاد؛ تجزیه و تحلیل مو
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
چکیده انگلیسی


• Oral morphine misuse is exceptional among young adolescents without history of addiction.
• Hair testing is useful to document an unsuspected misuse.
• Hair testing can contribute to police investigations.

Morphine sulfate misuse is essentially observed among regular heroin injectors. To our knowledge, primary addiction to morphine sulfate is exceptional, especially among young adolescents. A 13-year-old girl, with no history of addiction, was found dead with three empty blisters of Skenan® LP 30 mg at her side. Opiates were detected in biological fluids and hair by chromatographic methods. Blood analyses confirmed morphine overdose (free morphine: 428 ng/mL; total morphine: 584 ng/mL) and segmental hair analysis confirmed regular exposure over several months (maximum morphine concentration 250 pg/mg). Suspecting the victim's mother of recreational use of Skenan®, the magistrate ordered analysis of her hair, with negative results. From an epidemiological viewpoint, this case of oral morphine sulfate abuse in an adolescent with no previous history suggests the emergence of a new trend of morphine sulfate consumption. From a toxicological viewpoint, it demonstrates the value of hair testing, which documented the victim's regular exposure and made an important contribution to the police investigation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Forensic and Legal Medicine - Volume 36, November 2015, Pages 172–176
نویسندگان
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