کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10835182 1066047 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
On the hydrophobicity of nitrogen dioxide: Could there be a “lens” effect for NO2 reaction kinetics?
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
On the hydrophobicity of nitrogen dioxide: Could there be a “lens” effect for NO2 reaction kinetics?
چکیده انگلیسی
Solvent “lens” effects for the reaction kinetics of NO2 can be evaluated on the basis of published Henry's law constants for nitrogen dioxide in various solvents. Water-to-organic solvent partition coefficients were derived from Henry's law constants and used to assess the tendencies of NO2 toward fleeing the aqueous environments and concentrating in biological hydrophobic media. It is concluded, based only on the estimated aqueous medium-to-cell membrane partition coefficient for NO2, that such tendencies will be relatively small, and that they may account for an acceleration of chemical reactions in biological hydrophobic media with reaction kinetics that are first order on NO2 by a factor of approximately 3 ± 1. Thus, kinetic effects due to mass action will be relatively small but it is also important to recognize that because NO2 will tend to dissolve in cell membranes, reactions with cell membrane components will not be hindered by lack of physical solubility at these loci. In comparison to other gases, nitrogen dioxide is less hydrophobic than NO, O2 and N2.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nitric Oxide - Volume 21, Issue 2, 15 September 2009, Pages 104-109
نویسندگان
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