Elastic liposome-mediated transdermal immunization enhanced the immunogenicity of P. falciparum surface antigen, MSP-119

- Elastic liposomal formulation confers greater entrapment efficiency and enhanced penetration.
- Ultra deformable lipid vesicles overcome the poor permeability of antigens through skin.
- Robust and perdurable IgG-specific antibody and cytophilic isotype responses achieved.
- Greater serum level of IFNγ to conferring resistance to asexual blood stage human malaria.
- Effective immunoadjuvantivity and efficient transdermal delivery of PfMSP-119.