Efficacy of a capsule conjugate vaccine against inhalational anthrax in rabbits and monkeys

► An anthrax vaccine was produced by conjugating the capsule to a protein carrier. ► The anthrax capsule conjugate vaccine induced opsono-adherence antibodies. ► The capsule conjugate vaccine protected monkeys against inhalational anthrax. ► The capsule is the first non-toxin antigen shown to protect monkeys against anthrax.