Predictors of immune response and reactogenicity to AS03B-adjuvanted split virion and non-adjuvanted whole virion H1N1 (2009) pandemic influenza vaccines

► Further analysis of results from a trial of two pandemic vaccines was performed. ► Immune response was increased in those with post vaccination fever ≥38 °C. ► Those with previously given seasonal influenza vaccine had reduced immune responses. ► Immune response was greater with increased interval between doses. ► Atopy was associated with more reactions following adjuvanted vaccine.