Systematic annotation and analysis of “virmugens”-Virulence factors whose mutants can be used as live attenuated vaccines

► On virmugens, virulence factors whose mutants are used as live attenuated vaccines. ► Curation and analysis of bacterial, viral, and protozoan virmugens. ► Specific virmugen patterns are identified. ► Host genes specifically induced by virmugen vaccines are annotated. ► A web-based virmugen database is developed for query and analysis.