کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10969975 1103006 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The potential value of Clostridium difficile vaccine: An economic computer simulation model
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
The potential value of Clostridium difficile vaccine: An economic computer simulation model
چکیده انگلیسی
Efforts are currently underway to develop a vaccine against Clostridium difficile infection (CDI). We developed two decision analytic Monte Carlo computer simulation models: (1) an Initial Prevention Model depicting the decision whether to administer C. difficile vaccine to patients at-risk for CDI and (2) a Recurrence Prevention Model depicting the decision whether to administer C. difficile vaccine to prevent CDI recurrence. Our results suggest that a C. difficile vaccine could be cost-effective over a wide range of C. difficile risk, vaccine costs, and vaccine efficacies especially, when being used post-CDI treatment to prevent recurrent disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 28, Issue 32, 19 July 2010, Pages 5245-5253
نویسندگان
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