کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1242003 1495803 2015 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Applications of electrochemical immunosensors for early clinical diagnostics
ترجمه فارسی عنوان
استفاده از ایمونوسنزرهای الکتروشیمیایی برای تشخیص زودهنگام بالینی
کلمات کلیدی
بیوسنسور، بیومارکرهای سرطانی، ایمونوسنسور، بیوسنسورهای الکتروشیمیایی، تشخیص زودهنگام
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


• Electrochemical biosensors for cancer and cardiac biomarkers are reviewed.
• Biosensors are compared in terms of precision, reproducibility, regeneration, stability and specificity.
• More than 150 research papers focused on cancer biomarkers are discussed.

Cancer and cardiovascular diseases are the major threats to global health. Hence, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of these diseases. Electrochemical immunosensors are simple, rapid, reliable and inexpensive devices and they have sensitive detection limits to monitor both levels of the biomarkers in normal and patient serum. Due to the specific binding of antibody to its corresponding antigen, immunosensors based on antibody–antigen interaction are one of the most widely used analytical techniques in the quantitative detection of these diseases. The changed levels of markers in patients are associated with diseases. In this article the biosensors and biomarkers, which were commonly used in terms of monitoring the diagnosis and treatment of cancer and cardiac diseases, are reviewed. In addition, the developed biosensors are compared in terms of precision, reproducibility, regeneration, stability and specificity.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Talanta - Volume 132, 15 January 2015, Pages 162–174
نویسندگان
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