A novel target and pH dual-activatable fluorescent probe for precisely detecting hypochlorite in lysosomes

A novel dual-activatable fluorogenic probe CS has been rationally designed. This probe exhibited good sensitivity, high specificity and fast response towards HClO under the lysosomal acidic conditions, and it has been successfully applied for visualizing exogenous or endogenous HClO in lysosomes of living cells.Download : 216KB)Download :