Experimental study of culture for mouse fibroblast used conductive polymer films

The purpose of this study is to develop electrodes for electrical stimulation of the nervous system using conductive polymers, polypyrrole (PPy) and/or poly(3,4-ethylenedioxythiophene), PEDOT. We evaluated biocompatibility in fibroblast and/or myoblast of mouse. Cultured cells on PPy and/or PEDOT extended their neuritis and survived over a week. These experiments have demonstrated that conductive polymers such as PPy, PEDOT, etc. have high biocompatibility, and PPy and/or PEDOT are applicable to nerve stimulation electrodes.