کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2408254 1103164 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Expression of cytokine genes following pre- and post-hatch immunization of chickens with herpesvirus of turkeys
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Expression of cytokine genes following pre- and post-hatch immunization of chickens with herpesvirus of turkeys
چکیده انگلیسی
Induction of immune response as characterised by expression of cytokine genes in the spleen following immunization of pre- and post-hatch chickens with herpesvirus of turkeys (HVT) vaccine was studied. The pattern of expression of IFN-γ and IL-10 genes in pre-hatch immunized chickens was different from that observed in post-hatch HVT immunized chickens. This expression pattern of cytokine genes was associated with significantly higher HVT transcripts in pre-hatch immunized chickens than in post-hatch immunized chickens. In conclusion, HVT immunization in chickens, irrespective of the age of immunization, stimulates host response characterised by the expression of cytokine genes, such as IFN-γ and IL-10 in the spleen. However, the age of immunization appears to influence the temporal pattern of IFN-γ and IL-10 expression as well as replication of HVT.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 26, Issue 19, 2 May 2008, Pages 2369-2377
نویسندگان
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