کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2409020 1103202 2007 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A blowfly strike vaccine requires an understanding of host–pathogen interactions
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
A blowfly strike vaccine requires an understanding of host–pathogen interactions
چکیده انگلیسی

The phase-out of Mulesing by 2010 means the Australian wool industry requires immediate and viable alternatives for the control and prevention of blowfly strike, an economically important parasitic disease of sheep. In this review we have analysed previous research aimed toward the development of a vaccine against blowfly strike and the reasons why the approaches taken were unsuccessful at the time. Close scrutiny has provided new insight into this host–parasite interaction and identified new opportunities for the development of a vaccine. Here we propose that addressing immunosuppression together with the induction of cellular immunity is likely to result in an anti-blowfly strike vaccine, as opposed to the use of “standard” approaches aimed at inducing humoral immunity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 25, Issue 28, 9 July 2007, Pages 5133–5145
نویسندگان
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