کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2467689 1555404 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genetic variability and phylogeny of Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2) based on complete genomes
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Genetic variability and phylogeny of Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2) based on complete genomes
چکیده انگلیسی

Thirteen genomes of Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2) were obtained to examine the diversity and evolution of swine TTVs. Despite the low nucleotide identity reported, the genomic organization and transcriptional profiles of TTVs are similar. The nucleotide diversity for TTSuV1 was higher than TTSuV2, and the pattern of mutation among the ORFs was also different. Phylogenetic and genetic analyses support the proposed division of TTV into two species. TTSuV1 showed high levels of variability (>30%), with three different types (the third described for the first time) that may display a geographical structure. In contrast, TTSuV2 showed lower levels of variability (<15%), and no different types could be described. Larger values for the ratios of synonymous (dS) to non-synonymous (dN) base substitutions (dS/dN) were reported for the ORFs pointing to a certain level of selective constraint in TTV genomes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 148, Issues 2–4, 24 March 2011, Pages 125–131
نویسندگان
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