کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2787506 | 1154318 | 2012 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: New Understandings on Folliculogenesis/Oogenesis Regulation in Mouse as Revealed by Conditional Knockout New Understandings on Folliculogenesis/Oogenesis Regulation in Mouse as Revealed by Conditional Knockout](/preview/png/2787506.png)
In comparison to conventional knockout technology and in vitro research methods, conditional gene knockout has remarkable advantages. In the past decade, especially during the past five years, conditional knockout approaches have been used to study the regulation of folliculogenesis, follicle growth, oocyte maturation and other major reproductive events. In this review, we summarize the recent findings about folliculogenesis/oogenesis regulation, including the functions of four signaling cascades or glycoprotein domains that have been extensively studied by conditional gene deletion. Several other still fragmented areas of related work are introduced which are awaiting clarification. We have also discussed the future potential of this technology in clarifying gene functions in reproductive biology.
Journal: Journal of Genetics and Genomics - Volume 39, Issue 2, February 2012, Pages 61–68