کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2826095 1162201 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transcript elongation factors: shaping transcriptomes after transcript initiation
ترجمه فارسی عنوان
فاکتورهای انقباض رونوشت: شکل دادن ترانسکتیکوم ها پس از شروع رونویسی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
چکیده انگلیسی


• Factors regulating transcript elongation contribute to the control of gene expression.
• They facilitate RNA polymerase II progression through chromatin.
• Elongation control is involved in shaping transcriptomes and adjusting plant growth and development to internal and external cues.

Elongation is a dynamic and highly regulated step of eukaryotic gene transcription. A variety of transcript elongation factors (TEFs), including modulators of RNA polymerase II (RNAPII) activity, histone chaperones, and histone modifiers, have been characterized from plants. These factors control the efficiency of transcript elongation of subsets of genes in the chromatin context and thus contribute to tuning gene expression programs. We review here how genetic and biochemical analyses, primarily in Arabidopsis thaliana, have advanced our understanding of how TEFs adjust plant gene transcription. These studies have revealed that TEFs regulate plant growth and development by modulating diverse processes including hormone signaling, circadian clock, pathogen defense, responses to light, and developmental transitions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 19, Issue 11, November 2014, Pages 717–726
نویسندگان
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