کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2938543 | 1176944 | 2012 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Normalized End-Systolic Volume and Pre-Load Reserve Predict Ventricular Dysfunction Following Surgery for Aortic Regurgitation Independent of Body Size
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کلمات کلیدی
EDDVCFcNYHAEDVESDESVFPI - REITEnd-diastolic dimension - ابعاد انتهای دیاستولیکNew York Heart Association - انجمن قلب نیویورکContractility - انقباضechocardiography - اکوکاردیوگرافیleft ventricle - بطن چپEnd-systolic dimension - بعد سیستولیvalvular heart disease - بیماری قلبی دریچهEnd-diastolic volume - حجم انتهای دیاستولیکend-systolic volume - حجم سیستول پایینconfidence interval - فاصله اطمینانaortic regurgitation - نارسایی دریچه آئورت odds ratio - نسبت شانس هاEnd-systolic - پایان سیستولیکPre-load - پیش بارگیریejection fraction - کسری خروجیShortening fraction - کسری کوتاه
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Normalized End-Systolic Volume and Pre-Load Reserve Predict Ventricular Dysfunction Following Surgery for Aortic Regurgitation Independent of Body Size Normalized End-Systolic Volume and Pre-Load Reserve Predict Ventricular Dysfunction Following Surgery for Aortic Regurgitation Independent of Body Size](/preview/png/2938543.png)
چکیده انگلیسی
Pre-operative end-systolic volume (ESV) is predictive of outcome after surgery for severe aortic regurgitation. ESV is influenced by body size and reflects function and afterload, but not pre-load. Left ventricular (LV) chamber size and function were measured in 40 patients (ages 10 to 64 years) by echocardiography before and 7 months after operation and expressed as z-scores in addition to simple indexing. A functional pre-load index, a marker of pre-load reserve, was calculated. Independent risk factors for post-operative LV dysfunction included higher post-operative ESV z-score (odds ratio [OR]: 3.3, p = 0.006) and lower functional pre-load index (OR: 0.3, p = 0.03). ESV per square meter had similar power to the ESV z-score. The ESV uncorrected for body size underestimated risk in smaller patients and overestimated risk in larger patients (p < 0.002). Pre-load reserve is an independent risk factor for LV dysfunction after aortic valve surgery in patients with severe aortic regurgitation. Failure to correct ESV for body size introduces systematic bias to risk assessment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: JACC: Cardiovascular Imaging - Volume 5, Issue 6, June 2012, Pages 626-633
Journal: JACC: Cardiovascular Imaging - Volume 5, Issue 6, June 2012, Pages 626-633
نویسندگان
Thomas L. FRACP, John K. MB, PhD, Irene MSc, Paget F. FRACS, A. Kirsten FRACS, Nigel J. FRACP,