کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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30864 | 44510 | 2010 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Vitamin D, light and mental health Vitamin D, light and mental health](/preview/png/30864.png)
Vitamin D receptors and vitamin D metabolizing enzymes are present in the central nervous system. Calcitriol (the active vitamin D hormone) affects numerous neurotransmitters and neurotrophic factors, relevant for mental disorders. In the case of depressive disorders, considerable evidence supports a role of suboptimal vitamin D levels. However, the data are not conclusive and further studies are necessary. Especially, the relative importance of the pineal–melatonin system versus the vitamin D-endocrine system for the pathogenesis of seasonal affective disorders is presently unresolved. Two diagnoses, schizophrenia and autism, have been hypothetically linked to developmental (prenatal) vitamin D deficiency, however, also in adult patients, low levels have been reported, supporting the notion that vitamin D deficiency may not only be a predisposing developmental factor but also relate to the adult patients’ psychiatric state. Two cases are described, whose psychiatric improvement coincided with effective treatment of vitamin D deficiency.
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 101, Issue 2, 3 November 2010, Pages 142–149