کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3163879 1198751 2015 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adenoid cystic carcinoma of the head and neck – An update
ترجمه فارسی عنوان
سرطان آدنوئید کیستیک سر و گردن یک به روز رسانی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی


• Adenoid cystic carcinoma is an uncommon salivary gland tumor.
• Updated current state of the art on head and neck adenoid cystic carcinoma.
• Emphasis on pathobiological advances on head and neck adenoid cystic carcinoma.

SummaryThis article provides an update on the current understanding of adenoid cystic carcinoma of the head and neck, including a review of its epidemiology, clinical behavior, pathology, molecular biology, diagnostic workup, treatment and prognosis. Adenoid cystic carcinoma is an uncommon salivary gland tumor that may arise in a wide variety of anatomical sites in the head and neck, often with an advanced stage at diagnosis. The clinical course is characterized by very late recurrences; consequently, clinical follow-up should extend at least >15 years. The optimal treatment is generally considered to be surgery with postoperative radiotherapy to optimize local disease control. Much effort has been invested into understanding the tumor’s molecular biological processes, aiming to identify patients at high risk of recurrence, in hopes that they could benefit from other, still unproven treatment modalities such as chemotherapy or biological therapy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 51, Issue 7, July 2015, Pages 652–661
نویسندگان
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