کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3180000 | 1200487 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novedades en el diagnóstico y tratamiento del sÃndrome periódico asociado al receptor del factor de necrosis tumoral
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
امراض پوستی
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چکیده انگلیسی
Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is a rare autosomal dominant disease included in the group of autoinflammatory syndromes. It is characterized by recurrent episodes of fever and inflammation in different regions of the body. The main clinical manifestations are myalgia, migratory erythematous rash, periorbital edema, and abdominal pain. The diagnosis is reached using gene analysis and prognosis depends on the appearance of amyloidosis secondary to the recurrent episodes of inflammation. Tumor necrosis factor inhibitors and corticosteroids are the most widely used treatments. In recent years, significant advances have been made in the diagnosis and treatment of TRAPS, thanks to a better understanding of its pathogenesis. Dermatologists must be aware that the skin manifestations of TRAPS are particularly important, as they are often diagnostic.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Actas Dermo-Sifiliográficas - Volume 104, Issue 7, September 2013, Pages 617-622
Journal: Actas Dermo-Sifiliográficas - Volume 104, Issue 7, September 2013, Pages 617-622
نویسندگان
L. Aguado-Gil, I. Irarrazaval-Armendáriz, M. Pretel-Irazabal,