Pustulose exanthématique aiguë généralisée induite par l'application d'Algipan®

AGEP is drug-induced in more than 90% of cases, mostly after antibiotics, especially β-lactams and macrolides. Algipan® is a topical treatment containing mephenesin used for its analgesic and anti-inflammatory properties in adult muscular pain. No severe skin drug reactions due to this drug have been reported to date. Cases of AGEP induced by topical agents are rarely reported and our case is the first involving mephenesin. Our study suggests that topical mephenesin should be noted as a drug that may cause AGEP.