کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3189482 | 1586643 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Les tests épicutanés chez les patients atteints de dermatite atopique : les atopy patch tests
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
امراض پوستی
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چکیده انگلیسی
Exposure of atopic dermatitis (AD) patients to aeroallergens or food allergens can exacerbate or maintain the disease. Atopy patch tests (APTs) are able to identify these triggering factors and consist of the epicutaneous application of allergens for 48Â hours with evaluation of the resulting eczematous lesions after 48 and 72Â hours, according to the reading criteria of the European Task Force on Atopic Dermatitis (ETFAD). APTs show a higher specificity than skin prick and specific IgE tests, since the pathophysiological mechanism of the reaction induced is very similar to what occurs in AD lesions. The standardization of APTs to aeroallergens has brought a certain degree of reliability to this method, which is not the case for food APTs, where the positive predictive value must be improved in order to avoid any unnecessary dietary restrictions. Thus, optimization of APTs and furtherance of knowledge of the pathophysiology of eczemas could help to develop new immunobiological diagnostic methods and AD-specific immunotherapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annales de Dermatologie et de Vénéréologie - Volume 136, Issues 8â9, AugustâSeptember 2009, Pages 630-634
Journal: Annales de Dermatologie et de Vénéréologie - Volume 136, Issues 8â9, AugustâSeptember 2009, Pages 630-634
نویسندگان
A. Nosbaum, A. Hennino, A. Rozières, M. Vocanson, J.-F. Nicolas,