Factors that affect the allergic rhinitis response to ragweed allergen exposure

The rate of symptom development upon ragweed exposure was related to concomitant hypersensitivity to perennial allergens and grass pollen as determined by SPT and clinical history. The RQLQ was a powerful predictor of the priming response to ragweed, showing a dose-response-type association. These data suggest that a “prepriming” phenomenon is present in patients with SAR. No correlation was shown between symptomatic responses and degree of SPT reactivity.