کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3205793 | 1587562 | 2012 | 45 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An overview of clinical and experimental treatment modalities for port wine stains
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کلمات کلیدی
RPMPWSPDTIPLPDLFDANd:YAG - Nd: YAGImmunomodulators - ایمونومولاتورPhotodynamic therapy - درمان فتودینامیکRapamycin - راپامایسینFood and Drug Administration - سازمان غذا و داروPort wine stains - لکه های شراب بندرpulsed dye laser - لیزر رنگ پالسAngiogenesis inhibitors - مهار کننده های آنژیوژنزneodymium:yttrium-aluminum-garnet - نئودیمیم: یتریم-آلومینیوم-گارنتIntense pulsed light - نور پتانسیل شدید
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
امراض پوستی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Port wine stains (PWS) are the most common vascular malformation of the skin, occurring in 0.3% to 0.5% of the population. Noninvasive laser irradiation with flashlamp-pumped pulsed dye lasers (selective photothermolysis) currently comprises the gold standard treatment of PWS; however, the majority of PWS fail to clear completely after selective photothermolysis. In this review, the clinically used PWS treatment modalities (pulsed dye lasers, alexandrite lasers, neodymium:yttrium-aluminum-garnet lasers, and intense pulsed light) and techniques (combination approaches, multiple passes, and epidermal cooling) are discussed. Retrospective analysis of clinical studies published between 1990 and 2011 was performed to determine therapeutic efficacies for each clinically used modality/technique. In addition, factors that have resulted in the high degree of therapeutic recalcitrance are identified, and emerging experimental treatment strategies are addressed, including the use of photodynamic therapy, immunomodulators, angiogenesis inhibitors, hypobaric pressure, and site-specific pharmaco-laser therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 67, Issue 2, August 2012, Pages 289-304.e29
Journal: Journal of the American Academy of Dermatology - Volume 67, Issue 2, August 2012, Pages 289-304.e29
نویسندگان
Jennifer K. MD, Pedram MD, Guillermo PhD, Anne Margreet MD, Albert MD, PhD, Kristen M. MD, Michal PhD,