کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3208345 1587591 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Permanent chemotherapy-induced alopecia: Case report and review of the literature
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
Permanent chemotherapy-induced alopecia: Case report and review of the literature
چکیده انگلیسی

Reversible alopecia following chemotherapy is well recognized and typically not evaluated by dermatologists. However, there are an increasing number of reports of permanent chemotherapy-induced alopecia, typically following high-dose chemotherapy and subsequent bone marrow transplantation. We describe an unusual case of permanent alopecia in a patient who received adjuvant chemotherapy for breast carcinoma, and not a conditioning regimen before bone marrow transplantation. A unique histologic finding of replacement of anagen hair follicles by linear columns of basaloid epithelium is reported. We review the clinical and histologic findings of permanent chemotherapy-induced alopecia and speculate on its pathogenesis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 63, Issue 2, August 2010, Pages 333–336
نویسندگان
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