کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3210074 | 1587633 | 2007 | 7 صفحه PDF | دانلود رایگان |
BackgroundLymphomatoid papulosis (LyP) is a self-healing eruption in the spectrum of CD30+ lymphoproliferative disorders. The most common lymphoproliferative disorder associated with LyP is the most common form of cutaneous T-cell lymphoma: mycosis fungoides.ObjectiveWe sought to describe a distinct entity on the spectrum of CD30+ lymphoproliferative disorders.ResultsSeven patients presented with similar findings. Within a well-circumscribed area, the size and location of a patch of mycosis fungoides, these patients had continual eruptions of papulonodules that were histologically typical of LyP. The localized areas of involvement were treated as oligolesional mycosis fungoides and long-standing remissions occurred even after years of experiencing continuous localized eruptions. The clinical and histologic findings are reviewed and presented in a way to further the identification of patients with this entity.LimitationsThis distinct entity is only defined by 7 patients.ConclusionThe agmination of LyP-like papulonodules confined to a discrete circumscribed area is a distinct clinical subset within the spectrum of CD30+ lymphoproliferative disorders. The behavior of this entity is that of a progressive lymphoma that warrants therapy.
Journal: Journal of the American Academy of Dermatology - Volume 57, Issue 6, December 2007, Pages 1005–1011