کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3210388 1587619 2008 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Outcomes of melanoma in recipients of solid organ transplant
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
Outcomes of melanoma in recipients of solid organ transplant
چکیده انگلیسی

BackgroundThere is concern that the immunologic tumor malignant melanoma (MM) may have worse outcomes in immunosuppressed hosts than in the general population.ObjectiveWe sought to describe outcomes of MM in immunosuppressed solid organ transplant recipients and compare them with the general population.MethodsWe conducted a retrospective review of medical charts and pathology slides of cases of MM and solid organ transplantation between 1978 and 2007, with comparison of outcomes.ResultsIn all, 48 MMs were identified in 43 transplant recipients. No patient with MM before transplant receipt had melanoma recurrence, subsequent metastasis, or death caused by melanoma. Of patients with MM diagnosed after transplantation, metastases developed in 3 patients, and two patients died of melanoma.LimitationsRetrospective review and low number of cases are limitations.ConclusionsOutcomes of MM in immunosuppressed transplant recipients appeared similar to those in prognostically matched nonimmunosuppressed hosts. The small number of cases limited statistical comparisons.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Academy of Dermatology - Volume 59, Issue 3, September 2008, Pages 405–417
نویسندگان
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