کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3210605 | 1587637 | 2007 | 7 صفحه PDF | دانلود رایگان |

Graft-versus-host disease (GVHD) is a T cell–mediated disease seen most commonly after hematopoietic stem cell transplantation. Rarely, a GVHD-like disease can be seen in patients with malignant thymoma. We describe a 50-year-old man with malignant thymoma who developed skin, liver, and intestinal manifestations similar to that seen in GVHD. We also review other reported cases of GVHD-like manifestations in the setting of thymoma and propose “thymoma-associated multiorgan autoimmunity” as a name for this novel disease. Specifically, thymoma-associated multiorgan autoimmunity is defined as a disease of the liver, intestine, or skin, which on histopathology resembles GVHD but is seen in the setting of malignant thymoma and not after hematopoietic stem cell transplantation.
Journal: Journal of the American Academy of Dermatology - Volume 57, Issue 4, October 2007, Pages 683–689