کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3219011 1204423 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of Immune Cell Infiltrates during Squamous Carcinoma Development
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
Analysis of Immune Cell Infiltrates during Squamous Carcinoma Development
چکیده انگلیسی

Infiltration of leukocytes into tissue is a common feature of many physiological and pathological conditions. Histopathologically, the diversity of leukocytes that infiltrate a tissue associated with a pathophysiologic response cannot be appreciated and/or examined unless highly selective immunologic detection methods are utilized. Specific populations of infiltrating leukocytes into squamous tissues harboring pre-malignant and/or malignant keratinocytes have recently been demonstrated to play a functionally significant role in the pathogenesis of squamous carcinomas. To evaluate immune cell types and quantify changes in their relative presence and localization during multi-stage neoplastic progression, we performed flow cytometry and histochemical detection using lineage-selective markers. Herein, we provide detailed methodology facilitating these analyses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Investigative Dermatology Symposium Proceedings - Volume 11, Issue 1, September 2006, Pages 36–43
نویسندگان
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