کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
339981 | 548178 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Suicide and severe mental illnesses. Cohort study within the UK general practice research database
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
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چکیده انگلیسی
We aimed to evaluate suicide risk across the life-course in severe mental illnesses (SMI) including schizophrenia. Using survival analysis, we compared suicide risk in cohorts of 46,136 people with SMI and 300,426 without. The overall unadjusted hazard ratio (HR) for suicide in SMI was 12.97 (95% CI: 9.75–17.25). The unadjusted HRs differed by age band: 18–30 years: 19.56 (9.76–39.17); 30–50 years: 13.14 (8.64–19.99); 50–70 years: 16.39 (9.15–29.37); 70+: 3.25 (1.33–7.94). In schizophrenia, risk was significantly higher when young but marked risk persisted until age 70. Greatest risk was associated with: increased consultation rates; antidepressant prescriptions and living in less deprived areas.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Schizophrenia Research - Volume 99, Issues 1–3, February 2008, Pages 134–138
Journal: Schizophrenia Research - Volume 99, Issues 1–3, February 2008, Pages 134–138
نویسندگان
David Osborn, Gus Levy, Irwin Nazareth, Michael King,