کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4184346 | 1277308 | 2013 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Oral disease in relation to future risk of dementia and cognitive decline: Prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial Oral disease in relation to future risk of dementia and cognitive decline: Prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial](/preview/png/4184346.png)
ObjectiveExamine the association of oral disease with future dementia/cognitive decline in a cohort of people with type 2 diabetes.MethodsA total of 11,140 men and women aged 55–88 years at study induction with type 2 diabetes participated in a baseline medical examination when they reported the number of natural teeth and days of bleeding gums. Dementia and cognitive decline were ascertained periodically during a 5-year follow-up.ResultsRelative to the group with the greatest number of teeth (more than or equal to 22), having no teeth was associated with the highest risk of both dementia (hazard ratio; 95% confidence interval: 1.48; 1.24, 1.78) and cognitive decline (1.39; 1.21, 1.59). Number of days of bleeding gums was unrelated to these outcomes.ConclusionsTooth loss was associated with an increased risk of both dementia and cognitive decline.
Journal: European Psychiatry - Volume 28, Issue 1, January 2013, Pages 49–52