کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4189918 1278141 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
History, aetiology, and symptomatology of schizophrenia
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
پیش نمایش صفحه اول مقاله
History, aetiology, and symptomatology of schizophrenia
چکیده انگلیسی

Schizophrenia is a severe, chronic, often disabling mental illness with onset characteristically in early adulthood. This article reviews the historical concepts of schizophrenia by Kraepelin and Bleuler, and discusses recent developments in the aetiology of schizophrenia, with an emphasis on the interplay between biological, psychological, and social factors. Genetic factors play an important role in the aetiology, as they ‘programme’ the early development of the brain’s structure, including the neurotransmitter receptor systems. According to the stress–vulnerability model, environmental stress and high ‘expressed emotion’ can precipitate the onset as well as influence the course and outcome of the illness. Cannabis abuse has a significant impact on the risk of schizophrenia, particularly in individuals with biological vulnerability to develop the illness. Clinically, patients with schizophrenia present with symptoms comprising positive (first-rank) and negative symptoms.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry - Volume 7, Issue 10, October 2008, Pages 404–409
نویسندگان
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