کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5452908 | 1513834 | 2017 | 7 صفحه PDF | دانلود رایگان |
BackgroundTo prove the efficacy of cold atmospheric plasma (CAP) to inactivate mycobacteria in vitro, we tested the susceptibility of important mycobacterial species to evaluate potential alternative treatment options.MethodsWe tested 8 different mycobacterial species M. tuberculosis2 (MTB) (resistant against isoniazid (INH)), M. marinum, M. ulcerans, M. abscessus, M. chelonae, M. africanum, M. terrae and M. avium against two typical CAP devices, a low temperature atmospheric pressure plasma jet (APPJ) and a dielectric barrier discharge plasma (DBD). The tests followed a modified standard procedure by comparing obtained inhibition zones after irradiation of 3, 15, 30 and 60Â s on selective (Löwenstein-Jensen) medium.ResultsIrradiation by both sources proved high antimycobacterial killing effectiveness against all species including the INH-resistant strain of M. tuberculosis and a set of most important mycobacterial pathogens causing mycobacteriosis. Plasma irradiation
Journal: Clinical Plasma Medicine - Volumes 5â6, June 2017, Pages 1-7