Original research articleEvaluation the effectiveness of combinative treatment of cold plasma jet, Indonesian honey, and micro-well dressing to accelerate wound healing

A combinative treatment of cold plasma jet, honey solution, and micro-well dressing to accelerate acute wound healing of mouse skin was evaluated. A honey solution 1% in phosphate-buffered saline (PBS) 20 µL was dropped into micro-well dressing that is attached on an acute wound before a 2-min cold plasma treatment. An inclined treatment style plasma jet with a 45° gradient was used. An infrared thermal camera was used to monitor the fate of the solution. To evaluate its effect, macroscopic evaluation and general staining were conducted. It was revealed that a combination of that honey and plasma treatment may not be efficacious. However, the related procedure functionalising micro-well dressing may provide a new insight in how to combine plasma jets and other solutions in animal or human models for skin-oriented treatment.