کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5537708 | 1402354 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The 2015 global production capacity of seasonal and pandemic influenza vaccine
ترجمه فارسی عنوان
ظرفیت تولید جهانی 2015 واکسن آنفولانزای فصلی و پاندمی
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کلمات کلیدی
AFRRegion of the AmericasSouth-East Asia RegionWPRLMICAMREMRInfluenza - آنفلوانزا Production - تولیدGAP - شکافcapacity - ظرفیتSeasonal - فصلیAfrican region - منطقه آفریقاEuropean region - منطقه اروپاWestern Pacific Region - منطقه غرب غرب آسیاEastern Mediterranean Region - منطقه مدیترانه شرقیVaccine - واکسنpandemic - پاندمیSEAR - پیدا کردنLow-and middle-income countries - کشورهای کم درآمد و متوسط درآمدEUR - یورو
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
A global shortage and inequitable access to influenza vaccines has been cause for concern for developing countries who face dire consequences in the event of a pandemic. The Global Action Plan for Influenza Vaccines (GAP) was launched in 2006 to increase global capacity for influenza vaccine production to address these concerns. It is widely recognized that well-developed infrastructure to produce seasonal influenza vaccines leads to increased capacity to produce pandemic influenza vaccines. This article summarizes the results of a survey administered to 44 manufacturers to assess their production capacity for seasonal influenza and pandemic influenza vaccine production. When the GAP was launched in 2006, global production capacity for seasonal and pandemic vaccines was estimated to be 500Â million and 1.5Â billion doses respectively. Since 2006 there has been a significant increase in capacity, with the 2013 survey estimating global capacity at 1.5Â billion seasonal and 6.2Â billion pandemic doses. Results of the current survey showed that global seasonal influenza vaccine production capacity has decreased since 2013 from 1.504Â billion doses to 1.467Â billion doses. However, notwithstanding the overall global decrease in seasonal vaccine capacity there were notable positive changes in the distribution of production capacity with increases noted in South East Asia (SEAR) and the Western Pacific (WPR) regions, albeit on a small scale. Despite a decrease in seasonal capacity, there has been a global increase of pandemic influenza vaccine production capacity from 6.2 billion doses in 2013 to 6.4 billion doses in 2015. This growth can be attributed to a shift towards more quadrivalent vaccine production and also to increased use of adjuvants. Pandemic influenza vaccine production capacity is at its highest recorded levels however challenges remain in maintaining this capacity and in ensuring access in the event of a pandemic to underserved regions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 34, Issue 45, 26 October 2016, Pages 5410-5413
Journal: Vaccine - Volume 34, Issue 45, 26 October 2016, Pages 5410-5413
نویسندگان
Kenneth A. McLean, Shoshannaâ Goldin, Claudia Nannei, Erin Sparrow, Guido Torelli,