Inhibition effect of blunting Notch signaling on food allergy through improving TH1/TH2 balance in mice

Food allergy was inhibited by blunting Notch signaling through suppressing TH2 polarization, enhancing TH1 cell differentiation and promoting TH1/TH2 balance in mice. Notch signaling plays a key role in IgE-mediated food allergy.