Hypoxia Inducible Factor-1α and Vascular Endothelial Growth Factor Expression are Associated with a Poor Prognosis in Patients with Nasopharyngeal Carcinoma Receiving Radiotherapy with Carbogen and Nicotinamide

These results suggest that the expression of hypoxia-associated markers (HIF-1α and VEGF) may have prognostic significance in patients with nasopharyngeal carcinoma who receive radiation plus carbogen and nicotinamide, but further study is needed.